Abstract
Analysis of 79 Dacron interposition shunts performed at Emory University from 1971 to 1977 identified a number of preoperative characteristics that correlate with short-term and long-term morbidity. Initial hospital mortality was related to the degree of elevation of the bilirubin and serum glutamic oxaloacetic transaminase (SGOT), to the presence of encephalopathy and to the urgency of the shunt procedure. Cumulative survival correlated best with the preoperative SGOT and bilirubin values, but other variables, including the Child's classification, preoperative encephalopathy, serum albumin, and the age of the patient at the time of operation, also exhibited significant associations. The hospital mortality of 13% and cumulative mortality of 48% in this series are in substantial agreement with similar reports in the literature. This experience differs widely from that described by most authors, however, in two other important respects: 1) significant hepatic encephalopathy has been observed in 45% of these hospital survivors, and 2) almost one-quarter of these patients have experienced spontaneous shunt closure. Thus, major shunt related complications have occurred in 70% of the patients to date. This incidence of undesirable consequences raises a serious question concerning the continued use of the Dacron interposition shunt for elective portal decompression.
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Selected References
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- Belli L., Marni A. Alternative use of the interposition Dacron grafts in the treatment of portal hypertension. Clinical experience with 28 cases. J Cardiovasc Surg (Torino) 1978 Sep-Oct;19(5):527–534. [PubMed] [Google Scholar]
- Cameron J. L., Zuidema G. D., Smith G. W., Harrington D. P., Maddrey W. C. Mesocaval shunts for the control of bleeding esophageal varices. Surgery. 1979 Mar;85(3):257–262. [PubMed] [Google Scholar]
- Drapanas T., LoCicero J., 3rd, Dowling J. B. Hemodynamics of the interposition mesocaval shunt. Ann Surg. 1975 May;181(5):523–533. doi: 10.1097/00000658-197505000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Filtzer H. S., Rossi R., Wolfort F. G. Experience with interposition mesocaval shunt for management of variceal bleeding. Arch Surg. 1977 May;112(5):593–595. doi: 10.1001/archsurg.1977.01370050053008. [DOI] [PubMed] [Google Scholar]
- Fulenwider J. T., Nordlinger B. M., Millikan W. J., Sones P. J., Warren W. D. Portal pseudoperfusion: an angiographic illusion. Ann Surg. 1979 Mar;189(3):257–268. doi: 10.1097/00000658-197903000-00001. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GEHAN E. A. A GENERALIZED WILCOXON TEST FOR COMPARING ARBITRARILY SINGLY-CENSORED SAMPLES. Biometrika. 1965 Jun;52:203–223. [PubMed] [Google Scholar]
- Galambos J. T., Warren W. D., Rudman D., Smith R. B., 3rd, Salam A. A. Selective and total shunts in the treatment of bleeding varices. A randomized controlled trial. N Engl J Med. 1976 Nov 11;295(20):1089–1095. doi: 10.1056/NEJM197611112952001. [DOI] [PubMed] [Google Scholar]
- Koransky J. R., Galambos J. T., Hersh T., Warren W. D. The mortality of bleeding esophageal varices in a private university hospital. Am J Surg. 1978 Sep;136(3):339–341. doi: 10.1016/0002-9610(78)90290-8. [DOI] [PubMed] [Google Scholar]
- Malt R. B., Malt R. A. Tests and management affecting survival after portacaval and spenorenal shunts. Surg Gynecol Obstet. 1979 Aug;149(2):220–224. [PubMed] [Google Scholar]
- Nay H. R., Fitzpatrick H. F. Mesocaval "H" graft using antogenous vein graft. Ann Surg. 1976 Feb;183(2):114–119. doi: 10.1097/00000658-197602000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
- REYNOLDS J. T., SOUTHWICK H. W. Portal hypertension. Use of venous grafts when side to side anastomosis is impossible. AMA Arch Surg. 1951 Jun;62(6):789–800. [PubMed] [Google Scholar]
- Reichle F. A., Fahmy W. F., Golsorkhi M. Prospective comparative clinical trial with distal splenorenal and mesocaval shunts. Am J Surg. 1979 Jan;137(1):13–21. doi: 10.1016/0002-9610(79)90004-7. [DOI] [PubMed] [Google Scholar]
- Rikkers L. F., Rudman D., Galambos J. T., Fulenwider J. T., Millikan W. J., Kutner M., Smith R. B., 3rd, Salam A. A., Sones P. J., Jr, Warren W. D. A randomized, controlled trial of the distal splenorenal shunt. Ann Surg. 1978 Sep;188(3):271–282. doi: 10.1097/00000658-197809000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rosenthal D., Deterling R. A., Jr, O'Donnell T. F., Jr, Callow A. D. Interposition grafting with expanded polytetrafluoroethylene for portal hypertension. Surg Gynecol Obstet. 1979 Mar;148(3):387–390. [PubMed] [Google Scholar]
- Smith R. B., 3rd, Perdue G. D., Jr Early and late morbidity of portasystemic shunts including experience with seven H-grafts. Am J Gastroenterol. 1972 Oct;58(4):396–410. [PubMed] [Google Scholar]
- Thompson B. W., Casali R. E., Read R. C., Campbell G. S. Results of interposition "H" grafts for portal hypertension. Ann Surg. 1978 May;187(5):515–522. doi: 10.1097/00000658-197805000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
- YEOH K. S., EISEMAN B. Portal vein thrombosis: thrombectomy and porta-caval anastomosis with the use of a graft. Singapore Med J. 1962 Jun;3:64–67. [PubMed] [Google Scholar]
