Abstract
In a study of 545 patients who underwent vagotomies for repair of duodenal ulcers, 62 patients (11%) were found to have inadequately reduced pentapeptide and/or insulin-stimulated acid secretions three months after operation. The ulcers recurred in 14 patients within three to nine years (mean: four years) (23%, 95% confidence limits: 13-35). Postoperative acid production and acid reduction were equal in patients with and without ulcer recurrence. The patients who did not develop recurrent ulcers had significantly lower preoperative pentapeptide peak acid outputs and significantly shorter preoperative histories of ulcers than patients whose ulcers recurred.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Emås S., Borg I. The insulin test: negative and positive tests versus numerical values. Scand J Gastroenterol. 1975;10(6):609–616. [PubMed] [Google Scholar]
- Faber R. G., Russell R. C., Parkin J. V., Whitfield P., Hobsley M. The predictive accuracy of the postvagotomy insulin test: A new interpretation. Gut. 1975 May;16(5):337–342. doi: 10.1136/gut.16.5.337. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jensen H. E., Amdrup E. Follow-up of 100 patients five to eight years after parietal cell vagotomy. World J Surg. 1978 Jul;2(4):525–532. doi: 10.1007/BF01563693. [DOI] [PubMed] [Google Scholar]
- Kragelund E., Amdrup E., Jensen H. E. Pentapeptide and Insulin Stimulated Gastric Acid Secretion in Patients with Duodenal Ulcer before and after Selective Gastric Vagotomy and Antrum Drainage: A Comparison with Results Obtained from Studies before and after Parietal Cell Vagotomy with No Drainage Procedure. Ann Surg. 1972 Nov;176(5):649–652. doi: 10.1097/00000658-197211000-00013. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kronborg O. Gastric acid secretion and risk of recurrence of duodenal ulcer within six to eight years after truncal vagotomy and drainage. Gut. 1974 Sep;15(9):714–719. doi: 10.1136/gut.15.9.714. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pentagastrin as a stimulant of maximal gastric acid response in man. A multicentre pilot study. Lancet. 1967 Feb 11;1(7485):291–295. [PubMed] [Google Scholar]
- Stabile B. E., Passaro E., Jr Recurrent peptic ulcer. Gastroenterology. 1976 Jan;70(1):124–135. [PubMed] [Google Scholar]