Abstract
Our experience with use of a Silastic shunt for carotid endarterectomy is reviewed briefly, and the complication of shunt thrombosis despite intraoperative administration of heparin is noted. Of obvious importance are the reduction of blood flow and the possibility of embolization caused by accumulating thrombus. Shunt thrombosis has been abolished by the use of heparin-impregnated Silastic shunts. In experiments in dogs, such heparin-treated shunts showed greater thromboresistance than did untreated shunts.
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- Brenner W. I., Engelman R. M., Williams C. D., Boyd A. D., Reed G. E. Nonthrombogenic aortic and vena caval bypass using heparin-coated tubes. Am J Surg. 1974 May;127(5):555–559. doi: 10.1016/0002-9610(74)90316-x. [DOI] [PubMed] [Google Scholar]
- Falb R. D., Takahashi M. T., Grode G. A., Leininger R. I. Studies on the stability and protein adsorption characteristics of heparinized polymer surfaces by radioisotope labeling techniques. J Biomed Mater Res. 1967 Jun;1(2):239–251. doi: 10.1002/jbm.820010205. [DOI] [PubMed] [Google Scholar]
- GOTT V. L., WHIFFEN J. D., DUTTON R. C. HEPARIN BONDING ON COLLOIDAL GRAPHITE SURFACES. Science. 1963 Dec 6;142(3597):1297–1298. doi: 10.1126/science.142.3597.1297. [DOI] [PubMed] [Google Scholar]
- Grode G. A., Falb R. D., Crowley J. P. Biocompatibie materials for use in the vascular system. J Biomed Mater Res. 1972;6(4):77–84. doi: 10.1002/jbm.820060407. [DOI] [PubMed] [Google Scholar]
- Krause A. H., Ferguson T. B., Weldon C. S. Thoracic aneurysmectomy utilizing the TDMAC-heparin shunt. Ann Thorac Surg. 1972 Aug;14(2):123–132. doi: 10.1016/s0003-4975(10)65210-1. [DOI] [PubMed] [Google Scholar]
- Leininger R. I., Crowley J. P., Falb R. D., Grode G. A. Three years' experience in vivo and in vitro with surfaces and devices treated by the heparin complex method. Trans Am Soc Artif Intern Organs. 1972;18(0):312–315. doi: 10.1097/00002480-197201000-00079. [DOI] [PubMed] [Google Scholar]
- Mobin-Uddin K., Utley J. R., Bryant L. R., Dillon M., Weiss D. L. Experimental and clinical evaluation of heparin-impregnated cloth-covered cardiac valves used without systemic anticoagulation. Ann Thorac Surg. 1974 Apr;17(4):351–359. doi: 10.1016/s0003-4975(10)65663-9. [DOI] [PubMed] [Google Scholar]
- Mustard J. F. Hemostasis and thrombosis. Semin Hematol. 1968 Apr;5(2):91–106. [PubMed] [Google Scholar]
- Sharbrough F. W., Messick J. M., Jr, Sundt T. M., Jr Correlation of continuous electroencephalograms with cerebral blood flow measurements during carotid endarterectomy. Stroke. 1973 Jul-Aug;4(4):674–683. doi: 10.1161/01.str.4.4.674. [DOI] [PubMed] [Google Scholar]
- Sundt T. M., Jr, Sharbrough F. W., Anderson R. E., Michenfelder J. D. Cerebral blood flow measurements and electroencephalograms during carotid endarterectomy. J Neurosurg. 1974 Sep;41(3):310–320. doi: 10.3171/jns.1974.41.3.0310. [DOI] [PubMed] [Google Scholar]
- Sundt T. M., Sandok B. A., Whisnant J. P. Carotid endarterectomy. Complications and preoperative assessment of risk. Mayo Clin Proc. 1975 Jun;50(6):301–306. [PubMed] [Google Scholar]
- WHIFFEN J. D., DUTTON R., YOUNG W. P., GOTT V. L. HEPARIN APPLICATION TO GRAPHITE-COATED INTRAVASCULAR PROSTHESES. Surgery. 1964 Aug;56:404–412. [PubMed] [Google Scholar]