There was a mistake in Scheme 1 and Figure 1 as published. The images for Scheme 1 and Figure 1 were inadvertently interchanged during the publication process; the image displayed as Scheme 1 should be Figure 1, and the image displayed as Figure 1 should be Scheme 1.
SCHEME 1.
Overview of the literature search, screening, categorization, and narrative synthesis process used in this structured narrative review of Harpagophytum procumbens and NSAIDs.
FIGURE 1.
Schematic representation of the anti-inflammatory mechanisms of HP compared to NSAIDs. HP exerts anti-inflammatory effects through multiple pathways, including inhibition of MAPKs and NF-κB signaling, activation of PPAR-γ, and suppression of pro-inflammatory mediators (e.g., cytokines, COX-2, 5-LOX, cPLA2). In contrast, NSAIDs act mainly by inhibiting COX-2 and reducing PGE2 synthesis.
The corrected Scheme 1 and Figure 1 appear below.
The original version of this article has been updated.
Footnotes
Edited and reviewed by: Albino Martins, Universidade do Minho Instituto de Investigacao em Biomateriais Biodegradaveis e Biomimeticos, Portugal
Generative AI statement
Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.