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. 2026 Jul 30;31(15):2651. doi: 10.3390/molecules31152651

Correction: Cifuentes et al. Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta. Molecules 2020, 25, 520

Fredi Cifuentes 1, Javier Palacios 2,*, Jorge Bórquez 3, Adrián Paredes 3, Claudio Parra 4, Alejandra Bravo 1,3, Mario J Simirgiotis 5,*
PMCID: PMC13468623  PMID: 42588586

In the original publication [1] high-performance counter-current chromatography (HPCCC) was replaced by high-speed counter-current chromatography (HSCCC).

Error in Figure Caption

In the original publication, there was a mistake in Figure 3’s caption as published. High-performance counter-current chromatography (HPCCC) was used instead of high-speed counter-current chromatography (HSCCC). The corrected Figure 3 caption appears below.

Figure 3.

Figure 3

Structure of isolated flavonoids by high-speed counter-current chromatography (HSCCC).

Text Correction

There was an error in the original publication in Section 2.2, title: 2.2. Fast HPCCC Isolation of Major Compounds in N. ramosissima Methanol Extract.

A correction has been made to 2.2. Fast HSCCC Isolation of Major Compounds in N. ramosissima Methanol Extract.

In the paragraph of Section 2.2, HPCCC was replaced with HSCCC:

“The employment of immiscible solvent systems in our HSCCC machine allowed the fast isolation of the main five components (compounds 1–5) from a crude methanol extract of N. ramosissima.”

There was an error in the original publication in Section 3.7. Selection of the Solvent System for HPCCC.

A correction has been made to 3.7. Selection of the Solvent System for HSCCC.

In the paragraph of Section 3.7, HPCCC was replaced with HSCCC:

“According to the requirements for solvent systems in HSCCC [47], the selection was performed by a partition experiment of the crude extract using several solvent systems including (1) hexane:acetonitrile (stationary phase poorly retained in the coil), (2) hexane: methanol, (3) HEMWAT (n-hexane: ethyl acetate: methanol: water) and (4) n-hexane: ethanol: water at different volume ratios.”

References

With this correction, References 31, 32 and 33 have been updated:

  • 31.

    Azmir, J.; Zaidul, I.S.M.; Rahman, M.M.; Sharif, K.M.; Mohamed, A.; Sahena, F.; Jahurul, M.H.A.; Ghafoor, K.; Norulaini, N.A.N.; Omar, A.K.M. Techniques for extraction of bioactive compounds from plant materials: A review. J. Food Eng. 2013, 117, 426–436.

  • 32.

    Zhang, Q.-W.; Lin, L.-G.; Ye, W.-C. Techniques for extraction and isolation of natural products: A comprehensive review. Chin. Med. 2018, 13, 20. https://doi.org/10.1186/s13020-018-0177-x.

  • 33.

    Zakaria, S.M.; Kamal, S.M.M. Subcritical Water Extraction of Bioactive Compounds from Plants and Algae: Applications in Pharmaceutical and Food Ingredients. Food Eng. Rev. 2015, 8, 23–34.

The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Footnotes

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Reference

  • 1.Cifuentes F., Palacios J., Bórquez J., Paredes A., Parra C., Bravo A., Simirgiotis M.J. Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta. Molecules. 2020;25:520. doi: 10.3390/molecules25030520. [DOI] [PMC free article] [PubMed] [Google Scholar]

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