Chen J., Xi X., Xu X., and Lin Y., “De Novo Missense Variant in TP63 Gene: Insights on Clinical and Molecular Investigations,” Journal of Gene Medicine 27, no. 11 (2025): e70055, 10.1002/jgm.70055.
In the originally published version of this article, Figure 2A contained a facial photograph in which the patient's eyes were inadvertently left unobscured. In addition, visual markers (arrows) intended to indicate specific clinical features in Figure 2B and Figure 2D were not consistently displayed in the earlier version of the figure. Furthermore, because the pedigree was simplified to a two‐generation presentation in the final revised version, the proband identifier in the Figure 2 legend should be updated from (Ⅲ:12) to (II:3).
To address these issues, Figure 2 has been replaced with an updated version in which the patient's eyes in Figure 2A are appropriately obscured and the intended visual markers (arrows) in Figure 2B and Figure 2D are correctly shown. In addition, the proband identifier in the Figure 2 legend should be updated from (III:12) to (II:3). The corrected Figure 2 is provided below.
FIGURE 2 Clinical features of orofacial, ears, syndactyly, and panoramic radiograph of the proband (II:3). (A) Frontal photograph showing craniofacial and ectodermal features, including a wide interocular distance, saddle nose, thick upper lip, a postsurgical scar from cleft lip repair, sparse hair on the forehead, absence of the outer one‐third of the eyebrows, and sparse eyelashes. (B) Left external ear, with an arrow indicating stenosis of the external auditory canal. (C) Intraoral view of the mandible, showing severe tooth loss with only residual roots remaining. (D) Photograph of the feet, with an arrow pointing to soft tissue syndactyly involving the 3rd and 4th toes of the right foot. (E) Right external ear, showing a normal appearance for comparison. (F) Intraoral view of the maxilla, demonstrating the postsurgical status of an alveolar ridge cleft, partial tooth loss, and remaining teeth present as residual crowns or roots. (G) Panoramic radiograph revealing severe dentition defects in both the maxilla and mandible, with no visible successor permanent tooth germs in the edentulous regions and notable alveolar bone resorption.
The pedigree figure (Figure 1) has also been revised accordingly, and the corrected version is provided below for reference.
We apologize for this error.