Abstract
Virtual simulation (VS) is pivotal in undergraduate dental education for cognitive and preclinical training. Expanding VS adoption and artificial intelligence (AI) incorporation necessitate an evidence synthesis to clarify current landscapes, challenges, and future directions. Following the PRISMA-ScR guidelines and Arksey and O’Malley’s framework, this scoping review included 57 studies (2007–2025) to map the landscape of VS and its AI-driven future. The included VS systems could be broadly categorized into two generations, with first-generation systems supporting knowledge acquisition and second-generation systems supporting procedural skill development. VS applications spanned multiple dental subspecialties with uneven technological maturity and depth. With assessment of examinations, expert-rated performance, simulator-derived metrics, and learner-reported questionnaires, most studies reported that VS improved learner performance and confidence. Challenges persist regarding uncertain long-term knowledge retention, incomplete replication of clinical settings, resource-intensive implementation, and the limited role in education. This review further explored the implications of future AI–VS incorporation, including AI-driven virtual patients and tutors, fidelity enhancement, adaptive feedback, and personalized competency-based assessment.
Subject terms: Computational biology and bioinformatics, Health care, Mathematics and computing
Introduction
Simulation-based education has been consistently shown to enhance learning outcomes in medical education1,2. As a discipline emphasizing both theoretical knowledge and technical skill development equally, dental education has long relied on various simulation aids to support undergraduate education3,4. Since the establishment of the first dental surgery school in Baltimore, MD, USA, in 1840, simulation technology has been gradually integrated into dental education5. With the growth of educational demands, phantom-head simulators emerged in 18941,6. Nowadays, phantom-head simulators equipped with plastic teeth, handpieces, and water spray systems to simulate clinical scenarios have become an essential aid in dental education1. In the late 1990s, computer-supported virtual simulation (VS) was introduced into dental schools7. Due to its high fidelity in replicating clinical scenarios, VS has pioneered a new approach to learning dental motor skills and has become an increasingly important component of undergraduate dental education1,8.
From a technological perspective, VS has developed in an evolutionary path consisting of two distinct generations. The first generation focuses on basic cognitive skills and utilizes interactive video technology to enhance knowledge acquisition and establish standardized learning environments9,10. The second generation further optimizes standardized learning environments and emphasizes practical skills training. It integrates highly realistic head models with force feedback devices and partially incorporates haptic feedback and real-time assessment mechanisms7,11. However, both generations are still constrained by traditional technological frameworks and present apparent development bottlenecks. From an application perspective, VS has been integrated into all subspecialties and foundational disciplines of dental medicine1. It addresses core challenges in traditional teaching through three key approaches: anatomical visualization, basic procedural training, and high-risk surgical simulation12–14. However, current VS implementations still have limitations: they primarily focus on the development of fundamental clinical skills, while neglecting both advanced technologies and basic medical mechanisms. Additionally, they provide insufficient coverage of rare diseases and complex interdisciplinary cases1,15. From an outcome perspective, VS in dental education has been shown to improve students’ performances via objective and subjective assessments16,17. For objective assessments, some VS systems incorporate built-in assessment tools to evaluate students’ performance based on accuracy, while most assessments rely on students’ exam scores. Subjective assessments have mainly relied on questionnaires regarding students’ learning experiences. However, current VS assessment lacks the continuous trace for students’ performances, outcome-feedback adjustments and subsequent individualized learning settings, which fails to achieve competency-based learning trajectories11,18.
In recent years, the rapid development of artificial intelligence (AI) technology has provided a core driving force for innovation and transformation across all industries, and it has demonstrated enormous potential in optimizing teaching models and improving training quality19,20. Modern dental education has a growing imperative to equip students with advanced clinical skills, support individualized competency-based learning trajectories, and prepare them to manage complex and multidisciplinary clinical scenarios21. Parallel to these educational demands, the rapid evolution of AI technology is reshaping VS through AI integration. The integration of AI into VS systems could enable advanced teaching approaches, including adaptive learning, automated performance analytics, realistic scenario generation, and personalized feedback, collectively positioning VS implications for the incorporation of AI as a powerful driver of innovation in medical and dental education8,22,23. However, directly implemented empirical studies on AI-enabled VS in undergraduate dental education remain very limited, as advanced technologies like generative AI have not yet been fully implemented19,24. Thus, to meet the evolving demands of modern dental education, it is essential to develop a comprehensive understanding of the current landscape and the challenges of VS from an AI perspective.
This scoping review primarily aims to outline the landscape and challenges of VS in undergraduate dental education, while also identifying areas in which future AI incorporation may further enhance simulation-based teaching. In line with the objectives of this scoping review, our research questions (RQ) were listed as follows:
RQ1: What are the core technologies and methodologies of VS systems?
RQ2: What are the applied subdisciplines and contents of VS?
RQ3: What are the educational outcomes based on VS assessment systems?
RQ4: What specific challenges impede the implementation of VS systems?
Results
After conducting a thorough search, we found 1420 articles, which were carefully assessed for relevance and eligibility. Ultimately, 57 articles were included in this scoping review based on strict inclusion and exclusion criteria, published between 2007 and 2025 (Fig. 1). From the 57 published studies, VS was reported to be applied in the educational practice involving undergraduate dental students across 18 countries including China (24 studies), the United Kingdom (4), Saudi Arabia (4), Germany (4), Thailand (3), Qatar (3), Sweden (2), France (2), Malaysia (2), Brazil (1), Egypt (1), Greece (1), Ireland (1), Israel (1), Korea (1), Romania (1), Spain (1), and the United Arab Emirates (1). Collectively, these articles provide diverse insights into the application of VS in stomatology undergraduate education (Fig. 2).
Fig. 1. PRISMA flow diagram.
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram shows the detailed process of information retrieval and literature screening.
Fig. 2. Geographic distribution and publication trends of included studies.
A Distribution of studies reporting the use of VS in undergraduate dental education by continent. B Cumulative number of publications by year (2007–2025).
Overall, the methodological quality of the included studies was generally acceptable. Most studies showed reasonable clarity in their aims, basic design, and outcome reporting. However, a minority of studies had insufficiently reported methodological details in certain domains, which may introduce some risk of bias. These features should be considered when interpreting the reported educational benefits of VS.
Technologies and methodologies
While the types of VS used in undergraduate dental education have become increasingly diverse, they can be broadly categorized into four main types based on their core learning scenarios and practical orientation: virtual clinical scenarios, virtual dental models, virtual treatment planning, and practical operation simulators. Based on the relevant studies included in this scoping review, we further outline the developmental trajectory of VS in undergraduate dental education, which can be divided into two evolutionary stages. This generational classification was not based on publication year or proprietary platform names, but on the dominant technological architecture, interaction mode, and primary educational function reported across the included studies (Table 1 and Supplementary Table 1).
Table 1.
Condensed characteristics of virtual simulation applications in the included studies
| Author, year | Country/region | VS-type | Application scenario | Real instruments | Force feedback | Real-time feedback | Evaluation |
|---|---|---|---|---|---|---|---|
| Rees, 200738 | UK | Practical operation simulators | Cavity preparation | Yes | Not clear | Yes | Yes |
| Casap, 201155 | Israel | Practical operation simulators | Implant surgery | Yes | No | Yes | Yes |
| Lund, 201161 | Sweden | Virtual clinical scenarios, Practical operation simulators | Oral and maxillofacial surgery | Yes | Yes | Yes | Yes |
| Papadopoulos, 201370 | Greece | Virtual clinical scenarios | Behavior management in pediatric dentistry | No | No | Yes | Yes |
| Rosen, 201465 | Sweden | Practical operation simulators | Oral and maxillofacial surgery | Yes | Yes | Yes | Yes |
| Joseph, 201414 | France | Practical operation simulators | Implant surgery | Yes | Yes | Yes | Yes |
| Juan, 201631 | Spain | Virtual dental models | Dental morphology | No | No | Not clear | Yes |
| Tubelo, 201649 | Brazil | Practical operation simulators | Prosthodontic cementation | Yes | No | Yes | Yes |
| Al-Saud, 201739 | UK | Practical operation simulators | Preclinical operative dentistry | Yes | Yes | Yes | Yes |
| Shahriari-Rad, 201729 | UK | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Liu, 2018112 | China | Practical operation simulators | Crown preparation | Yes | No | Yes | Yes |
| Marei, 201887 | Saudi Arabia | Virtual clinical scenarios | Oral and maxillofacial surgery | No | No | Yes | Yes |
| Mirghani, 2018101 | UK | Practical operation simulators | Preclinical operative dentistry | Yes | Yes | Yes | Yes |
| Lone, 201932 | Ireland | Virtual dental models | Dental morphology | No | No | Yes | Yes |
| Zhang, 202056 | China | Virtual clinical scenarios, Practical operation simulators | Implant surgery | Yes | Not clear | Yes | Yes |
| Al-Saud, 202025 | Saudi Arabia | Practical operation simulators | Crown preparation | Yes | Yes | Yes | Yes |
| Liebermann, 202033 | Germany | Virtual dental models | Dental morphology | Yes | No | No | Yes |
| Mai, 202048 | Korea | Virtual dental models | Dental occlusion | No | No | No | Yes |
| Murbay, 202036 | China | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Reymus, 202034 | Germany | Virtual dental models | Root canal anatomy | No | No | No | Yes |
| Vincent, 202037 | France | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Yin, 202111 | Thailand | Practical operation simulators | Root canal treatment | Yes | Yes | Yes | Yes |
| Zhang, 202126 | China | Practical operation simulators | Periodontal treatment | Yes | Not clear | Yes | Yes |
| Ho, 202266 | China | Virtual dental models | Orthodontic treatment | No | No | No | Yes |
| Li, 202252 | China | Practical operation simulators | Crown preparation | Yes | Yes | Yes | Yes |
| Tee, 202269 | Malaysia | Virtual clinical scenarios | Oral mucosal diseases | No | No | Yes | Yes |
| Shetty, 202373 | United Arab Emirates | Virtual treatment planning | Implant surgery | No | No | No | Yes |
| Huang, 202357 | China | Practical operation simulators | Implant surgery | Yes | No | Yes | Yes |
| Ba-Hattab, 202344 | Qatar | Practical operation simulators | Root canal treatment | Yes | Yes | Yes | Yes |
| Alsufyani, 202312 | Saudi Arabia | Virtual dental models | Panoramic radiographic anatomy | Yes | No | Yes | Yes |
| Luo, 202350 | China | Virtual treatment planning | Removable prosthodontics | No | No | No | Yes |
| Petre, 202354 | Romania | Virtual dental models | Prosthodontics | No | No | No | Yes |
| Daud, 202378 | Qatar | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Liebermann, 2023113 | Germany | Virtual dental models | Dental morphology | No | No | No | Yes |
| Hamama, 202441 | Egypt | Practical operation simulators | Caries removal | Yes | Yes | No | Yes |
| Fu, 202413 | China | Practical operation simulators | Periodontal treatment | Yes | Yes | Yes | Yes |
| Duan, 202427 | China | Practical operation simulators | Root canal treatment | Yes | Not clear | Yes | Yes |
| Daud, 202417 | Qatar | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Buajeeb, 202477 | Thailand | Virtual clinical scenarios | Oral mucosal diseases | No | No | Yes | Yes |
| Li, 202442 | China | Virtual clinical scenarios | Rubber dam isolation | No | No | Yes | Yes |
| Wang, 202458 | China | Practical operation simulators | Periodontal treatment | Yes | Yes | Yes | Yes |
| Wei, 202443 | China | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Wu, 202459 | China | Practical operation simulators | Periodontal treatment | Yes | Yes | Yes | Yes |
| Yao, 202451 | China | Virtual clinical scenarios | Reception in prosthodontics | Yes | No | No | Yes |
| Nassief, 202435 | Saudi Arabia | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Peanchitlertkajorn, 202471 | Thailand | Virtual clinical scenarios | Dental clinic management | No | No | No | Yes |
| Liu, 202546 | China | Virtual dental models, Virtual clinical scenarios, Practical operation simulators | Apicoectomy | Yes | No | Yes | Yes |
| Hu, 202547 | China | Virtual clinical scenarios | Regenerative endodontics | No | No | Yes | Yes |
| Lv, 202540 | China | Practical operation simulators | Cavity preparation | Yes | Yes | Yes | Yes |
| Tang, 202574 | China | Practical operation simulators | Crown preparation | Yes | Yes | Yes | Yes |
| Cheng, 202560 | China | Practical operation simulators | Periodontal treatment | Yes | Yes | Yes | Yes |
| Huang, 202545 | China | Virtual clinical scenarios | Root canal treatment | No | No | Yes | Yes |
| Prinz, 202530 | Germany | Virtual clinical scenarios | Diagnosis and treatment in endodontics | No | No | Yes | Yes |
| Guo, 202563 | China | Virtual clinical scenarios | Oral and maxillofacial surgery | No | No | Not clear | Yes |
| Rehman, 202572 | Malaysia | Virtual clinical scenarios | Typical multidisciplinary clinical cases | No | No | Yes | Yes |
| Chen, 202567 | China | Virtual clinical scenarios | Orthodontic treatment | Not clear | Not clear | Yes | Yes |
| Liu, 202564 | China | Virtual dental models, Virtual clinical scenarios, Practical operation simulators | Orthognathic surgery | Yes | Not clear | Yes | Yes |
First-generation VS systems were defined as cognition-oriented environments that primarily relied on interactive video technology, standard 2D displays, or immersive virtual reality (VR) headsets to support knowledge acquisition, spatial understanding, and standardized procedural cognition. Their applications include: (1) Virtual clinical scenarios simulating disease-specific diagnostic and treatment pathways (e.g., endodontic procedures from diagnosis to treatment, or orthodontic workflows from initial consultation to staged therapy), thereby facilitating the development of clinical reasoning and standardized procedural skills; (2) Virtual dental models for teaching dental anatomy, morphology, and radiographic interpretation (e.g., 3D visualization of dental structures and identification of anatomical landmarks in panoramic and periapical radiographs), enabling multi-angle observation and spatial memory formation; (3) Virtual treatment planning simulating clinical decision-making processes (e.g., restoration design and implant placement planning), enabling students to practice treatment planning and procedural skills in risk-free environments while developing core clinical competencies.
Second-generation VS systems were defined as procedure-oriented simulation environments that built upon interactive video technology and further integrated virtual instrument operation modules with high-fidelity head models, force feedback devices and real-time performance assessment. Representative platforms in this category include Simodont25, Virteasy14, and UniDental26. These systems focus on developing students’ hand–eye–brain coordination through core clinical procedures such as carious tissue removal, dental preparation, periodontal scaling, root canal preparation, and filling14,25,27. By incorporating virtual instrument modules with realistic head models or force feedback systems, these advanced training environments enable comprehensive skill development. The latest advancements feature tactile feedback and real-time evaluation systems within virtual instruments, allowing students to perceive simulated dental tissue hardness and resistance during operation. The system simultaneously tracks operational trajectories, force control, and movement precision, while providing playback functionality, error detection, and instant correction prompts11,28. This enables students to familiarize themselves with procedures, instruments, and equipment before actual patient treatment, facilitating proactive, independent, and repeatable learning that significantly enhances the relevance and effectiveness of pre-clinical skill training (Fig. 3).
Fig. 3. Distribution of VS system types across different dental subspecialties in the included studies.
Functional categories of VS systems are stratified by subspecialty: cariology and endodontics, prosthodontics and implantology, periodontology, oral and maxillofacial surgery, dental morphology, orthodontics, oral mucosal diseases, and other specialities (pediatric dentistry and basic dental sciences).
Overall, the two generations differed more in their dominant teaching roles than in chronology alone. First-generation VS systems were primarily applied to visualization, case-based learning, and structured treatment planning, thereby supporting knowledge acquisition and standardized procedural cognition9,10. By contrast, second-generation systems were more closely associated with operative training tasks such as cavity preparation, periodontal scaling, root canal procedures, and implant simulation, with greater reliance on haptic feedback, realistic head models, and built-in performance evaluation11,25,29. These patterns suggest that the evolution of undergraduate dental VS has been marked by a shift from cognition-oriented digital support toward more procedure-oriented and feedback-rich simulation environments. Notably, empirical evidence of AI-integrated VS is exemplified by the pioneering work of Prinz et al. (2025). Their study successfully implemented a large language model (GPT) to act as a virtual patient for endodontic diagnostics, enabling students to engage in realistic, conversational clinical reasoning30. This specific application provides a tangible demonstration of how AI can transform traditional VS from static modules into dynamic, interactive learning environments8,22,23.
Applied subdisciplines and contents
VS is being increasingly integrated across dental subspecialties. The included studies report applications spanning dental morphology, cariology and endodontics, prosthodontics and implantology, periodontology, oral and maxillofacial surgery, orthodontics, oral mucosal diseases, pediatric dentistry, and basic dental sciences. Across these disciplines, the reported training items consistently serve several shared educational purposes, including anatomical visualization, clinical reasoning and decision-making, treatment planning, and psychomotor skills training (Table 2 and Supplementary Table 2).
Table 2.
Applications, educational outcomes, and challenges of virtual simulation across dental subspecialties
| Author, year | Subdiscipline | Training item | Assessment methods | Challenges |
|---|---|---|---|---|
| Rees, 200738 | Cariology and endodontics | G. V. Black Class I and II cavity preparation | Questionnaire | Incomplete equivalence to real-life clinical settings |
| Casap, 201155 | Prosthodontics and implantology | Implant surgery | Questionnaire, Operation test | Uncertain long-term retention of knowledge |
| Lund, 201161 | Oral and maxillofacial surgery | Mandibular third molar surgery | Questionnaire | Incomplete equivalence to real-life clinical settings |
| Papadopoulos, 201370 | Other | Pediatric dental communication and behavior management technology | Questionnaire | Incomplete equivalence to real-life clinical settings, non-substitutive supplement to traditional training |
| Rosen, 201465 | Oral and maxillofacial surgery | Mandibular third molar surgery | Operation test, Questionnaire | Non-substitutive supplement to traditional training |
| Joseph, 201414 | Prosthodontics and implantology | Implant surgery | Operation test | Uncertain long-term retention of knowledge |
| Juan, 201631 | Dental morphology | Morphological structures of the mandibular first molar | Theory test, Questionnaire | Incomplete equivalence to real-life clinical settings, non-substitutive supplement to traditional training |
| Tubelo, 201649 | Prosthodontics and implantology | Zinc phosphate cement manipulation | Theory test, Operation test | Uncertain long-term retention of knowledge |
| Al-Saud, 201739 | Cariology and endodontics | Hand skills training | Operation test | Non-substitutive supplement to traditional training |
| Shahriari-Rad, 201729 | Cariology and endodontics | Caries removal and cavity preparation | Theory test, Operation test | Non-substitutive supplement to traditional training, with a resources-intensive nature |
| Liu, 2018112 | Prosthodontics and implantology | Ceramic crown preparation | Questionnaire, Operation test | Incomplete equivalence to real-life clinical settings |
| Marei, 201887 | Oral and maxillofacial surgery | Impacted wisdom teeth and maxillofacial trauma | Theory test, Operation test | Incomplete equivalence to real-life clinical settings, resource-intensive nature, non-substitutive supplement to traditional training |
| Mirghani, 2018101 | Cariology and endodontics | Hand skills training | Operation test | Non-substitutive supplement to traditional training, Incomplete equivalence to real-life clinical settings |
| Lone, 201932 | Dental morphology | Identification of permanent teeth | Questionnaire, Theory test | Incomplete equivalence to real-life clinical settings, non-substitutive supplement to traditional training |
| Zhang, 202056 | Prosthodontics and implantology | Implant surgery | Theory test, Operation test, Questionnaire | Uncertain long-term retention of knowledge, Incomplete equivalence to real-life clinical settings |
| Al-Saud, 202025 | Cariology and endodontics | Clinical crown preparation | Operation test | Incomplete equivalence to real-life clinical settings |
| Liebermann, 202033 | Dental morphology | Tooth morphology | Questionnaire | Resources-intensive nature, non-substitutive supplement to traditional training |
| Mai, 202048 | Prosthodontics and implantology | Occlusal adjustment | Questionnaire, Theory test | Resources-intensive nature |
| Murbay, 202036 | Cariology and endodontics | SISTA Classification-Site 1 cavity preparation | Operation test | Non-substitutive supplement to traditional training |
| Reymus, 202034 | Dental morphology | Root canal anatomy | Theory test, Operation test, Questionnaire | Non-substitutive supplement to traditional training |
| Vincent, 202037 | Cariology and endodontics | G. V. Black Class II cavity preparation | Operation test | Incomplete equivalence to real-life clinical settings, non-substitutive supplement to traditional training |
| Yin, 202111 | Cariology and endodontics | Access cavity preparation | Operation test | Non-substitutive supplement to traditional training |
| Zhang, 202126 | Periodontology | Supragingival scaling | Theory test, Operation test, Questionnaire | Uncertain long-term retention of knowledge |
| Ho, 202266 | Orthodontics | Orthodontic diagnostic | Theory test | Incomplete equivalence to real-life clinical settings, non-substitutive supplement to traditional training |
| Li, 202252 | Prosthodontics and implantology | Ceramic crown preparation | Questionnaire | Incomplete equivalence to real-life clinical settings |
| Tee, 202269 | Oral medicine | Management of oromucosal lesions | Questionnaire, Theory test | Non-substitutive supplement to traditional training |
| Shetty, 202373 | Prosthodontics and implantology | Implant planning | Theory test | Uncertain long-term retention of knowledge |
| Huang, 202357 | Prosthodontics and implantology | Implant surgery | Questionnaire | Non-substitutive supplement to traditional training |
| Ba-Hattab, 202344 | Cariology and endodontics | Access cavity preparation | Questionnaire | Uncertain long-term retention of knowledge |
| Alsufyani, 202312 | Dental morphology | Panoramic radiographic anatomy | Questionnaire | Uncertain long-term retention of knowledge, non-substitutive supplement to traditional training |
| Luo, 202350 | Prosthodontics and implantology | Removable partial denture framework design | Theory test, Operation test, Questionnaire | Resources-intensive nature |
| Petre, 202354 | Prosthodontics and implantology | Partial edentulism cases treatment | Questionnaire | Uncertain long-term retention of knowledge |
| Daud, 202378 | Cariology and endodontics | G. V. Black Class I cavity preparation | Questionnaire, Operation test | Uncertain long-term retention of knowledge, Incomplete equivalence to real-life clinical settings, resources-intensive nature |
| Liebermann, 2023113 | Dental morphology | Tooth morphology | Questionnaire | Non-substitutive supplement to traditional training |
| Hamama, 202441 | Cariology and endodontics | Caries removal | Questionnaire | Incomplete equivalence to real-life clinical settings, resource-intensive nature, non-substitutive supplement to traditional training |
| Fu, 202413 | Periodontology | Ultrasonic periodontal scaling | Operation test, Questionnaire | Non-substitutive supplement to traditional training |
| Duan, 202427 | Cariology and endodontics | Access cavity preparation | Operation test, Questionnaire | Uncertain long-term retention of knowledge |
| Daud, 202417 | Cariology and endodontics | G. V. Black Class I cavity preparation | Focus group interview | Incomplete equivalence to real-life clinical settings |
| Buajeeb, 202477 | Oral medicine | Management of oromucosal lesions | Theory test, Questionnaire | Incomplete equivalence to real-life clinical settings |
| Li, 202442 | Cariology and endodontics | Rubber dam isolation technique | Operation test, Questionnaire | Uncertain long-term retention of knowledge |
| Wang, 202458 | Periodontology | Periodontal probing | Operation test, Questionnaire | Uncertain long-term retention of knowledge, Incomplete equivalence to real-life clinical settings |
| Wei, 202443 | Cariology and endodontics | Access and coronal cavity preparation | Operation test, Questionnaire | Non-substitutive supplement to traditional training, with uncertain long-term retention of knowledge |
| Wu, 202459 | Periodontology | Scaling and root planing | Questionnaire, Operation test | Uncertain long-term retention of knowledge |
| Yao, 202451 | Prosthodontics and implantology | Clinical reception | Operation test | Incomplete equivalence to real-life clinical settings |
| Nassief, 202435 | Cariology and endodontics | Hand skills training | Focus group interview | Uncertain long-term retention of knowledge |
| Peanchitlertkajorn, 202471 | Other | Dental practice management | Theory test, Questionnaire | Non-substitutive supplement to traditional training |
| Liu, 202546 | Cariology and endodontics | Apicoectomy | Theory test, Operation test, Questionnaire | Non-substitutive supplement to traditional training |
| Hu, 202547 | Cariology and endodontics | Regenerative endodontics | Theory test, Operation test, Questionnaire | Non-substitutive supplement to traditional training |
| Lv, 202540 | Cariology and endodontics | G. V. Black Class I, II and V cavity preparations | Questionnaire, Operation test | Incomplete equivalence to real-life clinical settings, resources-intensive nature |
| Tang, 202574 | Prosthodontics and implantology | Metal-ceramic crown preparation | Questionnaire, Operation test | Incomplete equivalence to real-life clinical settings |
| Cheng, 202560 | Periodontology | Subgingival scaling and root planing | Questionnaire, Operation test | Incomplete equivalence to real-life clinical settings |
| Huang, 202545 | Cariology and endodontics | Root canal filling | Questionnaire, Operation test, Theory test | Incomplete equivalence to real-life clinical settings |
| Prinz, 202530 | Cariology and endodontics | Endodontic diagnostics and emergency treatment | Questionnaire | Incomplete equivalence to real-life clinical settings |
| Guo, 202563 | Oral and maxillofacial surgery | Temporomandibular joint surgery | Questionnaire, Theory test | Incomplete equivalence to real-life clinical settings |
| Rehman, 202572 | Other | General clinical learning, patient communication and diagnosis | Questionnaire | Uncertain long-term retention of knowledge |
| Chen, 202567 | Orthodontics | Orthodontic treatment process | Questionnaire | Non-substitutive supplement to traditional training |
| Liu, 202564 | Oral and maxillofacial surgery | Orthognathic surgery | Questionnaire, Theory test | Incomplete equivalence to real-life clinical settings, resources-intensive nature |
In dental morphology education, VS supports tooth morphology learning through digital visualization tools. Mobile-based instruction was reported as non-inferior to physical models and offers practical advantages in portability and cost31. Augmented reality (AR) applications enable the overlay of 3D tooth models with touch-based manipulation31. Desktop tools support tooth identification aligned with the FDI tooth-numbering system and provide real-time feedback32. VR headsets enable immersive virtual laboratories for macroscopic anatomy33, root canal observation34, and anatomical landmark identification on panoramic radiographs12. Stereoscopic visualization may further support spatial learning beyond conventional 2D instruction35.
In cariology and endodontics, VR-based training enables cavity preparation using haptic-enabled handpieces and foot pedals36–38. Virtual drilling and material-removal tasks are used to develop fine motor skills and hand–eye coordination29,39,40. Clinical simulations address caries management41 and the complete endodontic workflow, including rubber dam isolation42, access cavity preparation27,43, pulp chamber preparation44, and obturation45. Advanced techniques such as apicoectomy and pulp regeneration have also been incorporated46,47. Generative AI-powered virtual patients (GPT-4) have been applied to teach differential diagnosis of pulpal versus periodontal pain30.
In prosthodontics, VS supports theoretical instruction on occlusion48, adhesive materials49, removable partial denture design50, and patient reception51. Haptic simulators enable training in crown, inlay, and veneer preparation52,53. Integration with 3D printing extends hands-on practice54. In oral implantology, virtual navigation and haptic feedback facilitate surgical planning55 and support site localization, positioning, drilling, and osteotomy14,55,56. VR headsets enable systematic instruction of the complete implant workflow57.
In periodontology, instruction focuses on probing58, ultrasonic scaling, and root planing13,26,59,60. Haptic styluses guide standardized six-step protocols. Real-time evaluation assesses instrument angulation and force control, supporting precision training in periodontal therapy59,60.
In oral and maxillofacial surgery, VS addresses complex anatomy and higher-risk procedures. Systems simulate clinical decision-making using authentic cases61. Reported applications include inferior alveolar nerve block62, temporomandibular joint management63, and orthognathic surgery64. Extraction simulators train core skills for third molar removal, including bone removal, sectioning, and elevation, with automated quantification of tissue resection61,65.
In orthodontics, VS-based instruction covers diagnosis and treatment planning. Students use electronic models for occlusal analysis and tooth-size measurement66 and learn complete treatment sequences for Angle Class II Division 1 malocclusion67.
In oral medicine, virtual cases and simulated clinics reinforce diagnostic knowledge and clinical reasoning. Gamified scenarios enhance recognition of typical mucosal conditions68. Virtual clinics simulate patient–clinician communication in safe, repeatable environments69.
Other applications include pediatric dentistry, clinic management, and multidisciplinary training. One study used virtual scenarios involving an 8-year-old patient and a parent to develop pediatric communication skills70. A gamified virtual clinic taught management skills such as infection control and spatial planning71. A virtual dental clinic (VDC) integrating multidisciplinary cases supports pre-clinical training and complex case learning72.
Overall, VS has already been broadly integrated into undergraduate teaching across dental subspecialties and basic disciplines. However, its technological maturity remains uneven. Fields such as orthodontics, oral mucosal diseases, pediatric dentistry, and some basic dental sciences areas still rely mainly on first-generation applications, which are largely centered on theoretical learning and doctor–patient communication through virtual case libraries and three-dimensional models, with limited practical operation modules66,68,70. In contrast, more procedure-intensive disciplines, including endodontics, prosthodontics and implantology, periodontology, and oral and maxillofacial surgery, have more often adopted second-generation systems based on VR/AR integration, force feedback, and full-process procedural simulation11,13,52,65. These inter-disciplinary differences appear to be mainly related to the complexity of the target skills, the degree of haptic or immersive support required, and the maturity of the available simulation systems7.
Assessment methods and outcomes
The effectiveness of VS-based dental education is appraised to ensure it meets the evolving needs of undergraduate trainees. Evaluations are typically organized into four complementary strands: (1) Knowledge acquisition and retention: Most trials employ pre- and post-training theoretical examinations, quizzes or MCQ batteries to quantify learning gains26,36,67,73. (2) Practical competence: Operative competence is measured with expert-scored practical tests on synthetic resin teeth27, pig mandibles46, periodontal pathology models13,59,60 or phantom-head crown preparations74, frequently supplemented by simulator-generated metrics such as residual calculus rate59,60, drilling accuracy verified by CBCT/fluoroscopy56, and number of attempts or total preparation time65. (3) Skill transfer and clinical readiness: transfer is assessed through laboratory transfer tests26,56, standardized-patient Mini-CEX encounters51, and case-design exercises50. (4) User experience and program satisfaction: usability is captured via the System Usability Scale30, iterative questionnaires33,38,57,64, online or face-to-face focus groups, and attitudinal surveys. Several implementations also apply Miller’s pyramid18 or formative feedback algorithms to guide reflective practice18.
Across studies, undergraduate competencies improved after VS training, which reinforced both theory and practice. Virtual dental models visualize teeth, root canals, occlusion, and edentulous or orthodontic cases, enabling students to explore anatomy interactively without entering a dissection laboratory and thereby improving comprehension and retention32,34,66. Virtual treatment planning systems allowed undergraduates to repetitively design implants, removable partial dentures, or rubber-dam protocols under variable clinical conditions, thereby standardizing scheme formulation training42,50,73. Virtual clinical scenario systems embedded VS within simulated patient encounters, offering case-based training that mirrors real settings, fosters communication skills, and sharpens clinical reasoning30,69,75. VS-based case learning enhances knowledge acquisition, retention, and transfer to clinical contexts, ultimately improving diagnostic accuracy and clinical-reasoning instruction30,75. Practical operation simulators offered a risk-free, repeatable, and real-time feedback environment in which students master procedures, instruments, and equipment before treating patients36,43. Deployed across disciplines, these systems train hand–eye coordination, fine motor skills, access cavity preparation, endodontics, periodontics, extractions, and implant or prosthodontic procedures, ensuring thorough and standardized pre-clinical training13,46,74.
VS provides repeatable, immersive and instant feedback training, which significantly increases undergraduate dental students’ confidence in pre-clinical skills3,36,43. Most studies employed five-point Likert scales to evaluate satisfaction and educational impact; students consistently rated the approach as useful, informative and understanding-enhancing17,57,74. In implant planning and dental anatomy modules, students overwhelmingly selected VR as their preferred future learning tool, indicating strong perceived efficacy33,73. Platforms such as Simodont reinforce students’ sense of control over procedural details through multidimensional visualization and unlimited practice, thereby boosting confidence36,76. Although some students noted that haptic fidelity remains inferior to conventional phantom heads and advocated for closer integration6, VS has already significantly enhanced self-efficacy in aseptic technique, access cavity preparation, periodontal therapy and other core skills, providing a solid psychological and technical bridge to the clinical setting3,42,59 (Table 2).
Challenges
In pursuit of advanced undergraduate dental pre-clinical training, the application of VS is faced with multifaceted challenges, including uncertain long-term retention of knowledge12,42,59,72, incomplete equivalence to actual clinical settings25,51,63,77, heavy reliance on digital and instructional resources29,48,50,78 and non-substitutive supplement to traditional training11,13,47,71 (Table 2).
Uncertain sustained knowledge retention
As previously described, contemporary VS systems have been increasingly involved in core knowledge and skills across subdisciplines, facilitating students’ rapid, short-term acquisition of foundational knowledge. Most studies found that VS improved undergraduates’ initial knowledge acquisition through short-time performance assessment. However, uncertainties remain regarding its long-term educational effectiveness, particularly in terms of sustained knowledge retention36,49,56,73. As novel teaching methods, VS generated potential novelty effects, which may help students to improve the instant performance in pre-clinical training79. A study on digital learning methods has found that the mobile VR group demonstrated a drop in perceived usefulness and behavior intention after 3 months of use80. This phenomenon may be attributed to the limited and isolated implementation of VS, which fails to integrate knowledge and skills into a coherent developmental system72,81. Consequently, the fragmented learning pattern undermines learners’ deep cognitive engagement and raises concerns about sustained knowledge retention across the entire professional life cycle of dentists27,54,81.
Incomplete replication to real-world clinical settings
One of the major challenges of VS lies in its incomplete replication of the complexities and unpredictability of real-world clinical settings17,29,39,41. Real-world clinical situations involve a wide spectrum of disease presentations, anatomical variations, resource limitations, personalized patient communication, and multidisciplinary treatment (MDT) coordination, among numerous other dynamic factors30,61,69. However, most existing VS systems operate within a closed ecosystem characterized by limited databases, restricted interoperability, and delayed updates in treatment guidelines and research advancements1,81. Consequently, these systems predominantly rely on standardized, pre-set models designed for repetitive and deliberate practice40,53,57,81. While such an ecosystem effectively enables students to refine procedural techniques in a controlled, risk-free environment that safeguards patient safety, it simultaneously raises concerns regarding the translatability of simulation-acquired skills to authentic clinical practice25,37. The absence of continuously updated clinical data and diversified case repositories constrains students’ exposure to the variability intrinsic to real-world scenarios82. As a result, the current closed ecosystem of VS may impede the development of students’ adaptive problem-solving abilities, critical thinking, and competence in managing complex clinical challenges that evolve alongside contemporary dental practice51,70,82. These limitations may be further shaped by differences in local technological ecosystems and the availability of mature simulation platforms.
Resources-intensive nature
The resource-intensive nature of VS is one of the most prominent challenges for wide and continuous application, which adds financial and educator burden. Implementing VS requires digital resources involving equipment, software, network and multimedia materials, which brings a large financial burden to establish VS programs. For instance, a single high-fidelity mannequin can cost upwards of $50,000, without the additional expenses for software, maintenance, and upgrades29,33,83. Devices with inferior features and lower costs could damage the teaching outcomes with unfavorable interactive experience, including lower resolution visual performance, lagged feedback and poor availability1,84. Limited by adaptations between teaching platforms and subdisciplines, schools have to build specialized platforms for each subspecialty, adding extra teaching costs40,64. Moreover, studies have indicated that the VS program necessitates professional instructions from teachers to achieve optimal teaching goals, which demands ongoing development and support for teachers85,86. Dongru Chen et al. proposed that teachers devoted a large amount of time and energy to developing the VR software by communicating with the engineers67. Due to the resource-intensive nature, VS training called for the development of a cost-effective solution and highly compatible universal platforms, ensuring access for high-quality pre-clinical training1,48,50. In addition, differences in institutional resources, infrastructure readiness, and platform accessibility may also contribute to uneven adoption and implementation across educational settings.
Non-substitutive supplement to traditional training
Numerous studies have concluded that VS could not completely replace traditional training but serves as a supplement13,32,47,71. The main reason is that VS systems cannot fully replicate the clinical practice32,41. Thus, how to facilitate effective VS training programs remains a great challenge in the development of high-quality pre-clinical training. Since global adoption of VS has been a growing tendency, it is a novel teaching paradigm to integrate simulation training with other training modalities, including problem-based learning, interdisciplinary training programs, multimedia materials and inverted classroom49,50,69,87.
Discussion
With the increasing maturity of VS, its role in undergraduate dental education will evolve from an auxiliary teaching tool to a core infrastructure, reshaping curriculum design, teaching implementation, and competency assessment1,7,19. Based on the current evidence synthesized in this review, a forward-looking agenda for the future incorporation of AI into dental VS is proposed19,24,88. It outlines the development directions of dental AI–VS incorporation from the perspectives of technology7, application13, and assessment methods36, aiming to provide guidance for educators and institutions in constructing a sustainable, scalable, and student-centered virtual learning ecosystem (Fig. 4). Although direct empirical evidence on AI-integrated VS remains limited at present, these perspectives may help identify promising directions for future research and educational innovation.
Fig. 4. The core development directions for the incorporation of AI into dental VS systems.
The overarching developmental objective of VS in undergraduate dental education is to move beyond conventional technological frameworks and application-level constraints by establishing a next-generation AI–VS incorporation paradigm. In this framework, AI technologies function as the central enabler of end-to-end innovation across five interrelated dimensions, including intelligent virtual patients and AI tutors, enhancing virtual simulation fidelity, intelligent teaching content, intelligent supplementary of disciplinary background and personalized adaptive learning.
From the technological perspective, the incorporation of AI into dental VS may reshape core system functions, including intelligent virtual patients, AI tutors, haptic realism, and scene fidelity. Although the current second-generation VS systems have achieved remarkable results in clinical operation simulation and real-time assessment, their core framework is still constrained by traditional simulation teaching, making it difficult to meet the demand for personalized competency development in undergraduate stomatology education35,36,39. At present, the application of cutting-edge technologies such as generative AI in VS systems is still in the exploration stage, with a lack of mature solutions and models. This also constitutes a key direction for the research and development of the third-generation AI–VS incorporation19,30.
On one hand of technology, future development may promote the innovative use of intelligent virtual patients and AI tutors. Driven by generative AI and large language models (LLMs), future virtual patients may move beyond the static dialog limitations of traditional systems and simulate more diverse doctor–patient communication scenarios across different dental subspecialties30,89,90. This enables learners to improve the accuracy of medical history collection and empathy in doctor–patient communication through repeated practice51. Meanwhile, AI tutors support multi-modal interactions such as voice questioning and operation analysis, providing real-time expert-level feedback on key links, including instrument selection and treatment plan design22,89. This effectively addresses the shortcomings of traditional teaching, such as limited faculty resources and inadequate supervision coverage, and builds a bridge connecting simulation training with real clinical diagnosis and treatment65,75.
On the other hand, the fidelity of simulators can be further enhanced. In terms of haptic feedback optimization, AI technology breaks away from the limitation of traditional systems that rely on simplified physical equations84,91,92. By deep learning massive biomechanical data of real clinical operations, it constructs mechanical models to accurately replicate the differences in hardness, elasticity, and operational resistance of oral hard and soft tissues, thereby improving the clinical adaptability of practical skills11,29,36,52. In terms of scene visualization, in-depth integration of AI and AR technology seamlessly overlays virtual treatment plans and anatomical landmark annotations onto real-time images or 3D-printed models93–95. This significantly improves the clinical realism of the training environment and provides technical support for high-fidelity scene simulation54.
From the application perspective, the incorporation of AI into dental VS should be adapted to the educational objectives, technological maturity, and practical training needs of different dental subspecialties. The findings of this review suggest that undergraduate dental VS has already achieved broad disciplinary coverage, but its technological maturity remains uneven across subspecialties1,7. Building on this pattern, future AI incorporation should not follow a uniform pathway across dental disciplines19. Instead, differentiated upgrading strategies may be needed according to the educational objectives, technological readiness, and practical training demands of different subspecialties89. Preliminary exploratory applications in endodontics also suggest that AI may first emerge in areas where simulation systems are already relatively mature and where structured diagnostic or procedural workflows are well established11,23,30.
Future development may focus on implementing differentiated optimization and upgrading paths for dental subspecialties at different technological stages, promoting the iteration of VS teaching towards intelligence19,89. For subspecialties still in the first-generation technology stage, the transformation should focus on generative AI and LLMs30,90, combined with hardware such as lightweight VR devices and force feedback control components15,91, to construct a virtual diagnosis and treatment system with dynamic disease progression, intelligent Q&A interaction, and diagnosis and treatment logic guidance. Simultaneously, practical training modules should be supplemented to make up for the shortcomings in skill development15,16. For core operational subspecialties that have adopted second-generation technologies, the focus is on improving the quality and efficiency of operative training13,28,36. Core data such as students’ operation force parameters, instrument movement paths, error types, and durations are accurately collected, and personalized competency profiles are constructed through deep learning algorithms to dynamically adapt to the training needs of students with different foundations11,25,96.
Additionally, AI may help address the limitations of teaching content and efficiently construct high-quality teaching resources19,89. On one hand, it integrates multi-modal data such as CBCT images and digital intraoral impressions to reconstruct high-fidelity operation carriers with complete diagnosis and treatment information97. On the other hand, it focuses on the teaching gaps in cutting-edge disciplinary technologies, rare diseases, and complex multidisciplinary cases98,99. Based on treatment guidelines and massive literature of each subspecialty, it constructs a complex case simulation library covering all dental subspecialties68,77,99, and builds a multidisciplinary team VS platform with a dynamically updated professional knowledge base30,89,90. This ensures the timeliness, authority, and clinical relevance of teaching content, guides undergraduates to establish systematic clinical thinking, and improves their ability to diagnose and treat complex cases46,77.
From the assessment perspective, the incorporation of AI into dental VS may support more continuous, objective, and personalized competency-based evaluation. Most existing studies lack adequate longitudinal assessments100. Additionally, significant differences exist in the evaluation tools adopted by different teaching programs, with a lack of unified standards and quantitative systems16. This limitation severely hinders cross-study benchmarking, result recognition, and systematic review of teaching effectiveness, failing to meet the demand for competency-oriented personalized education. Therefore, there is an urgent need to establish a systematic, multi-level, and dynamic evaluation framework based on AI, integrating real-time performance analysis, phased skill transfer assessment, and continuous user feedback to realize iterative optimization of teaching schemes and precise improvement of educational outcomes1,11,25.
The core of AI empowerment lies in constructing a personalized adaptive evaluation mechanism, which addresses the subjectivity, lag, and homogenization of traditional evaluation methods22. Relying on multi-dimensional sensors in VS systems, AI captures real-time core data of learners, including instrument movement trajectories, force application characteristics, operation accuracy, duration, and error frequency96,101,102. After feature extraction via deep learning algorithms96, the system objectively quantifies skill deficiencies through visualization tools such as three-dimensional heat maps, trajectory playback, and error annotation11. It then generates targeted feedback and stepwise training recommendations, overcoming the subjective and ambiguous limitations of experience-based evaluation25,39. Based on full-cycle evaluation data, the system establishes a dynamically updated personalized competency profile for each learner, accurately identifying their proficiency levels in knowledge mastery, practical operation, critical thinking, and other dimensions22,88. Subsequently, it automatically adjusts training content: strengthening basic operational training and detailed guidance for learners with weak foundations, and expanding complex case drills for those who meet competency standards22, thereby supporting active and repeatable self-directed learning3,103. This personalized adaptive evaluation mechanism aligns preclinical skill training more closely with individual competency development needs, facilitating the achievement of competency-oriented personalized training goals for stomatology undergraduates22,88.
Despite these potential benefits, the incorporation of AI into dental VS also raises several important concerns that must be addressed before large-scale implementation to ensure clinical safety and pedagogical integrity19,24. Algorithmic bias remains a primary concern. If AI models are trained on non-representative datasets, they may produce skewed diagnostic suggestions, potentially compromising health equity104,105. Privacy and data security are equally paramount, as the integration of student performance and clinical imaging into AI ecosystems requires robust encryption to prevent sensitive data leaks89,106. Ethically, the “black-box” nature of some AI tools poses a challenge to the development of critical thinking, necessitating a “human-in-the-loop” approach where AI acts as a co-pilot rather than a substitute for faculty mentorship107,108. Finally, the field suffers from a lack of large-scale, cross-institutional validation. Moving forward, AI tools must undergo rigorous clinical trials to prove that their simulated environments translate effectively into superior real-world operative competence19,20.
The transition toward AI–VS incorporated dental education presents significant practical challenges that institutions must address to ensure a realistic and sustainable implementation19,24. Financially, the primary barrier is the high capital expenditure required for advanced hardware29,33. For instance, AI-integrated implant navigation systems necessitate substantial investment in optical tracking sensors and haptic feedback devices14,84. While AI can eventually reduce costs by automating the creation of patient-specific models from existing CT libraries, the initial “entry price” remains a major hurdle for many dental schools29,40. Technologically, institutional infrastructure must evolve toward cloud-native architectures capable of high-speed, real-time data synchronization84,91. In applications like implant navigation, any latency between the physical tracking sensors and the AI evaluator can compromise the objective assessment of drilling precision, entry-point deviation, and depth control14,55,56. Without robust network support and seamless integration of clinical data (e.g., DICOM and STL files), the fidelity of the simulation is significantly diminished57,94. Pedagogically, faculty training represents the most critical pivot point41,75. The educator’s role must transition from traditional clinical observation to big data-driven mentorship20,89. This requires instructors to develop the ability to interpret complex AI-generated outputs, such as surgical “precision heatmaps” and trajectory logs, to provide targeted feedback11,25. This shift necessitates a profound change in instructional methodology and extensive institutional support for retraining15,67. Ultimately, a realistic transition requires a phased approach. The approach starts with modular AI tools before moving toward fully integrated ecosystems, while it simultaneously bridges the socio-technical gap in faculty expertise19,20,89.
Several limitations of the current evidence base should be considered when interpreting the findings of this review. A substantial proportion of studies originated from a single country, and some were concentrated around a limited number of specific commercial or locally developed platforms1,91. Although this pattern reflected the distribution of currently available eligible evidence rather than preferential selection, it may limit the generalizability of the findings to other educational settings7,16. Therefore, the findings should be interpreted as reflecting broader trends and shared challenges in undergraduate dental VS rather than favoring any particular country or platform. More multi-center studies from diverse educational and technological contexts are needed to strengthen global applicability7,16. Despite these limitations, the current evidence still provides a useful basis for considering future VS development and AI incorporation8,19.
Methods
Study design
This scoping review was conducted in accordance with the PRISMA-ScR guidelines109. A descriptive approach based on Arksey and O’Malley’s five-stage framework was employed110: (1) identifying the research question; (2) identifying relevant studies; (3) selecting studies; (4) charting the data; and (5) collating, summarizing, and reporting the results. In addition, to provide methodological context for interpreting the evidence base, a brief critical appraisal of the included studies was conducted.
Identifying the relevant studies
The search strategy was developed around four core concepts: VS-related technologies, educational context, undergraduate training, and dental discipline. The core search terms comprised the following keywords: (“Augmented Reality” OR “Virtual Reality” OR haptic OR simulation) AND (educat* OR curriculum OR course OR program OR “educational methodology” OR “teaching method*”) AND (undergraduate OR “pre-postgraduate”) AND (dentistry OR oral OR dental OR dentist* OR odontol* OR stomatol*).
A wide-open systematic search of the literature was conducted in PubMed, ERIC (Institute of Education Sciences [IES], Washington, DC), Scopus™ (Elsevier B.V., Amsterdam, The Netherlands), and Web of Science (Clarivate Analytics, Philadelphia, PA) for records published up to October 2025. General controlled vocabulary (MeSH terms) and keywords were used where appropriate, and the search syntax was adapted to the indexing system and search interface of each database. Although the search itself was not limited by language, only full-text articles published in English were included during the study selection process.
Eligibility criteria and study selection
The inclusion criteria were as follows: (1) original research evaluating the educational use, implementation, or effectiveness of VS in dental or stomatology education; (2) participants were undergraduate dental or stomatology students; and (3) eligible study designs were not restricted and included a range of study types, such as randomized controlled studies, non-randomized comparative studies, descriptive studies, and relevant qualitative studies.
Studies were excluded if they: (1) did not examine VS as a core educational intervention or application; (2) did not focus on undergraduate dental or stomatology education; (3) were not original research articles, such as reviews, editorials, commentaries, conference abstracts, or study protocols; or (4) were not published in English.
Three reviewers participated in the two-stage screening process. Before formal screening, the reviewers aligned the eligibility criteria and screening procedures through discussion to ensure consistency in study selection. In the first stage, titles and abstracts were independently screened by two reviewers according to the predefined inclusion and exclusion criteria. In the second stage, all full-text articles that passed the initial screening were independently reviewed by two of the three reviewers. The reviewers held regular meetings to clarify the screening criteria and collectively resolve disagreements throughout the selection process. The final set of included studies was subsequently confirmed by the author team. Additionally, the reference lists of selected papers were manually analyzed to identify any relevant manuscripts that may have been missed during the electronic database search or other grey literature sources (Fig. 1).
Critical appraisal of included studies
A brief critical appraisal of the included studies was conducted using the Mixed Methods Appraisal Tool (MMAT), version 2018111, to provide methodological context for interpreting the evidence base. Given the scoping nature of this review and the heterogeneity of eligible study designs, the appraisal was intended to support interpretation of the findings rather than to determine study eligibility.
Charting the data
The authors extracted information from the included articles, including basic study information, subject theme, VS system, training item, assessment methods, outcomes, and challenges. The data were extracted by three reviewers, and any inconsistencies were resolved through discussion.
Supplementary information
Acknowledgements
This study was funded by the Undergraduate Education Quality Program of Sun Yat-Sen University, Medical Education Research Project by the Chinese Society of Medical Education and National Center for Health Professions Education Development (2025A06), Undergraduate Teaching Reform Research Project of Clinical Teaching Bases of Guangdong Province (2025JD015), and Higher Education Research Project of the 14th Five-Year Plan of Guangdong Association of Higher Education (25GZD001). The funder played no role in study design, data collection, analysis and interpretation of data, or the writing of this manuscript.
Author contributions
S.C. contributed to conception, design, drafted, and critically revised the manuscript. L.Q. and X.D. contributed to conception and drafted the manuscript. P.Y., X.L., S.H. and J.X. (Jiankun Xu) contributed to conception and figure design. J.X. (Jieyun Xu) and Z.C. contributed to conception and critically revised the manuscript. All authors gave final approval and agreed to be accountable for all aspects of the work.
Data availability
No datasets were generated or analyzed during the current study.
Competing interests
The authors declare no competing interests.
Footnotes
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
These authors contributed equally: Shijie Chen, Longshiyu Qiu, Xiaowen Du.
Contributor Information
Jieyun Xu, Email: xujy273@mail.sysu.edu.cn.
Zetao Chen, Email: chenzet3@mail.sysu.edu.cn.
Supplementary information
The online version contains supplementary material available at 10.1038/s41746-026-02806-z.
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Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Supplementary Materials
Data Availability Statement
No datasets were generated or analyzed during the current study.




