Skip to main content
The Journal of Physiology logoLink to The Journal of Physiology
. 1970 Jun;208(2):279–289. doi: 10.1113/jphysiol.1970.sp009119

Conduction velocity in myelinated nerve fibres of Xenopus laevis

N A Hutchinson, Z J Koles, R S Smith
PMCID: PMC1348748  PMID: 5500723

Abstract

1. The relationship between conduction velocity and nerve diameter in single myelinated nerve fibres from Xenopus laevis was measured and was found to be linear.

2. The relationship between conduction velocity and temperature in nerve fibres of various diameters was measured over the range 15-30° C and was found to be linear for each fibre.

3. The slope of the conduction velocity—temperature relationship was directly proportional to the diameter of the nerve fibre.

4. The form of the conduction velocity—temperature relationship was determined by numerical solution of the Frankenhaeuser—Huxley equations for the case of a propagated action potential. The computation predicted that conduction velocity is a linear function of temperature over the range studied.

Full text

PDF
279

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. FRANKENHAEUSER B., HUXLEY A. F. THE ACTION POTENTIAL IN THE MYELINATED NERVE FIBER OF XENOPUS LAEVIS AS COMPUTED ON THE BASIS OF VOLTAGE CLAMP DATA. J Physiol. 1964 Jun;171:302–315. doi: 10.1113/jphysiol.1964.sp007378. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. FRANKENHAEUSER B., WALTMAN B. Membrane resistance and conduction velocity of large myelinated nerve fibres from Xenopus laevis. J Physiol. 1959 Oct;148:677–682. doi: 10.1113/jphysiol.1959.sp006317. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Frankenhaeuser B. Computed action potential in nerve from Xenopus laevis. J Physiol. 1965 Oct;180(4):780–787. doi: 10.1113/jphysiol.1965.sp007731. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Franz D. N., Iggo A. Conduction failure in myelinated and non-myelinated axons at low temperatures. J Physiol. 1968 Dec;199(2):319–345. doi: 10.1113/jphysiol.1968.sp008656. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goldman L., Albus J. S. Computation of impulse conduction in myelinated fibers; theoretical basis of the velocity-diameter relation. Biophys J. 1968 May;8(5):596–607. doi: 10.1016/S0006-3495(68)86510-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Paintal A. S. Effects of temperature on conduction in single vagal and saphenous myelinated nerve fibres of the cat. J Physiol. 1965 Sep;180(1):20–49. [PMC free article] [PubMed] [Google Scholar]
  7. RUSHTON W. A. H. A theory of the effects of fibre size in medullated nerve. J Physiol. 1951 Sep;115(1):101–122. doi: 10.1113/jphysiol.1951.sp004655. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Smith R. S., Lännergren J. Types of motor units in the skeletal muscle of Xenopus laevis. Nature. 1968 Jan 20;217(5125):281–283. doi: 10.1038/217281a0. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES