Abstract
Background
Demographic transitions are reshaping health needs and challenging the sustainability of health governance, with the coordination of population and health services systems closely connected to these processes. This study investigates China’s population and health services systems from 2010 to 2022, aiming to explore the spatiotemporal evolution and key driving factors of their coupling coordination.
Methods
Data were obtained from the China Statistical Yearbook and China Health Statistics Yearbook, covering 31 provinces from 2010 to 2022. An evaluation model was developed to assess the coupling coordination degree (CCD) between the population and health services systems. Spatial autocorrelation analysis was employed to examine spatial dependence, and a Spatial Durbin Model (SDM) was applied to identify key driving factors.
Results
From 2010 to 2022, the development indices of China’s population and health services systems rose steadily, with the CCD increasing from 0.407 to 0.835, indicating a progression from initial imbalance toward advanced coordination. Regionally, the pattern of “east–strong, central–rising, west–weak” persisted, though disparities have diminished as central and western regions steadily caught up. Spatial analysis confirmed significant dependence and stable in provincial CCD, with patterns dominated by “high–high” clusters in the Yangtze River Delta and Beijing–Tianjin–Hebei region, which gradually extended into central provinces, and by persistent “low–low” clusters in the west and northeast, alongside several outliers. Spatial econometric results identified government health expenditure, health insurance coverage, digital and transport infrastructure as significant positive drivers, with government health expenditure and digital development showing stronger cross-regional spillovers.
Conclusion
Coordination between the population and health services systems improved substantially, although regional disparities persisted. Further progress requires closer alignment between demographic change and health service capacity. Differentiated regional strategies are therefore needed: economically and resource-advantaged regions could harness agglomeration and spillover effects through cross-regional collaboration; central provinces should consolidate their catch-up momentum and strengthen their regional service capacity; and western and other low-coordination regions, facing population mobility and ageing pressures, should prioritise targeted fiscal transfers, workforce retention incentives and improved service accessibility to promote more equitable and sustainable development.
Keywords: Population system, Health services system, Coupling coordination degree, Spatiotemporal evolution
Instruction
Profound demographic transitions are reshaping health needs. These changes are posing challenges to the sustainability of health governance in China and worldwide. Population ageing, declining fertility, rapid urbanization, and changing morbidity profiles have collectively increased the demand for more diverse and continuous health services [1]. These demographic and epidemiological shifts manifest in rising burdens of chronic diseases, mental health conditions, and multimorbidity, as well as widening inequalities in service utilization across regions and population groups [2–4]. At the same time, the erosion of traditional family support networks and increasing dependency ratios have added further strain to formal health systems [5, 6]. In this context, the health service system serves as the core supply framework for meeting population health needs and ensuring equitable access to essential services [7, 8]. Its performance and sustainability, however, are also inherently influenced by demographic dynamics, as population change is closely associated with variations in the scale and structure of health service demand [9–11].
From a social-ecological perspective, the population and health services systems can be regarded as interacting subsystems [12, 13]. The population system, defined by size, structure and spatial distribution, generates health service demand, while the health services system constitutes the institutional supply side that allocates resources and delivers care [9, 11, 14]. Their relationship can thus be conceptualised as a dynamic demand–supply interaction [11, 15], providing the basis for analysing how demographic change aligns with service capacity in the pursuit of sustainable health governance [16, 17]. Building on this view, previous studies have examined the links between population dynamics and health-related subsystems from several perspectives. One line of research has focused on older populations, analysing the alignment between their health service needs and utilisation patterns, and assessing the adequacy of delivery systems in meeting age-related demands [18–21]. Other studies have analysed shifts in population health status and disease burden under conditions of growing mobility and migration, underscoring the emerging challenges faced by both medical and public health services [22–25]. A further strand of research has emphasised the role of preventive, integrated and coordinated health services in improving health outcomes [26, 27]. While these studies provide important insights, analyses of how population structural characteristics are embedded within health service systems remain insufficient, and comprehensive assessments of their coupled development are still lacking. This issue is particularly pertinent in China, where a large population base, rapid demographic transitions in ageing and urbanisation, and relatively constrained health resources have raised critical questions about the extent to which the health services system can adapt to demographic changes and maintain effective coordination with the population system.
Given the new normal of population growth and the emerging requirements for high-quality population development, examining the coupling and coordination between the population system and the health services system provides a useful approach to assess how well current health services adapt to demographic transitions and to identify their remaining limitations. Building on existing research, this study adopts a demand–supply perspective to examine the spatiotemporal evolution of coupling coordination between the two systems in China from 2010 to 2022 at national, regional, and provincial levels. It further explores spatial spillover effects to reveal inter-provincial dynamics and identifies the driving factors associated with the alignment between demographic change and health service capacity. The findings are expected to provide empirical evidence on the interaction between demographic dynamics and the health services system, enrich understanding of system coordination, and offer insights to support the optimisation of health governance.
Theoretical and conceptual framework
Population system
From a social-ecological perspective, the population system constitutes a key social subsystem that interacts continuously with the economy, society, and health [12, 13]. Demographic transition theory views population change as a dynamic process shaped by fertility, mortality, and migration [5]. Research on population dynamics typically emphasises three dimensions: size, structure, and spatial distribution [9, 11, 21, 28]. These dimensions not only describe the internal functioning of the population system but also establish how demographic change translates into health service demand.
Population size is closely associated with the overall volume of health needs [29]; population structure, including age composition and dependency ratios, influences the type and intensity of demand; and spatial distribution, reflected in density, rural–urban patterns and migration, affects the equity of resource allocation [29, 30]. This tripartite framework has been widely applied in demographic and public health studies, offering a clear basis for linking demographic dynamics with health service demand. Accordingly, the population system is generally regarded as the demand-generating side of health governance.
Health services system
Within the health governance framework, the health services system is commonly understood as the institutional supply side responsible for organising and delivering services in response to population health needs [14, 15, 31]. More broadly, the World Health Organization defines a health system as encompassing all organisations, people and actions whose primary purpose is to promote, restore, or maintain health [32]. This definition extends beyond service delivery to include governance, financing, pharmaceuticals, technologies, and community-based initiatives.
In some studies, the term “health services system” is used more narrowly, referring either to the institutional arrangements through which preventive, curative, and rehabilitative services are delivered, or to the organisational structures of service provision across different administrative levels [10, 20, 29, 33]. Despite differences in scope, these perspectives converge in conceiving the health services system as the organised supply dimension most directly connected to population health demand.
Building on these definitional distinctions, existing frameworks further characterise the health services system as inherently multidimensional. The WHO “six building blocks” approach identifies service delivery, health workforce, information systems, essential medicines and technologies, financing, and governance as the core elements of effective functioning [32]. Other frameworks emphasise stewardship, financing, resource generation, and provision, or focus on outcomes such as efficiency, quality, and equity [34]. While differing in emphasis, these approaches consistently highlight the health services system as a mechanism that integrates resource mobilisation, effective service provision, and equitable coverage, thereby linking institutional arrangements to population health needs.
Interaction between the population system and the health services system
From a demand–supply perspective, the population system represents the source of health service needs, while the health services system constitutes the institutional supply side that responds to these needs [9, 11, 15]. Population size influences the overall volume of demand; structural shifts such as ageing or changing dependency ratios modify its type and intensity; and spatial patterns of density, urban–rural distribution, and migration generate regional disparities in access and utilisation [29, 30]. On the supply side, the health services system responds through resource allocation, service delivery and the assurance of accessibility and equity [15–17, 20, 21].
When demand and supply are aligned, the system functions more efficiently and equitably; when misaligned, shortages, inefficiencies, or spatial inequalities may arise [18, 29, 35]. This dynamic interaction provides the theoretical foundation for analysing the coupling and coordination of the two systems, underscoring the practical importance of aligning demographic change with service capacity to achieve sustainable health governance.
Building on this perspective, this study develops a conceptual framework to operationalise the interaction between the population and health services systems. The population system is defined as the demand side, characterised by size, structure, population density, and spatial distribution, whereas the health services system is defined as the supply side, characterised by health resources, health service provision and efficiency, and health management and coverage. To evaluate the alignment between demographic change and service capacity, the coupling coordination degree model is applied. Figure 1 presents this conceptual framework.
Fig. 1.

Conceptual framework of the interaction between the population system and the health services system
Materials and methods
Data source
The data for this study were obtained from statistical yearbooks covering the period from 2010 to 2022, including the China Health Statistics Yearbook and the China Statistical Yearbook [36, 37]. Administrative data at the national, regional, and provincial levels were compiled into a balanced spatiotemporal panel dataset. Following the classification defined in the China Health Statistics Yearbook, regions were divided into the three major spatial units: East, Central and West. The eastern region comprises 11 provinces and municipalities: Beijing, Tianjin, Hebei, Liaoning, Shanghai, Jiangsu, Zhejiang, Fujian, Shandong, Guangdong and Hainan; the central region includes Shanxi, Jilin, Heilongjiang, Anhui, Jiangxi, Henan, Hubei and Hunan; and the western region includes Inner Mongolia, Guangxi, Chongqing, Sichuan, Guizhou, Yunnan, Tibet, Shaanxi, Gansu, Qinghai, Ningxia and Xinjiang. Taiwan, Hong Kong and Macao, China, were not included in the analysis because relevant comparable data were unavailable.
The period 2010–2022 was selected for three reasons. First, considering the availability and quality of data, this timeframe provides access to a consistent and comprehensive set of high-quality national statistics, supporting the reliability, comparability, and accuracy of analysis at both national and provincial levels. Secondly, the policy background was considered. Since the launch of China’s new round of healthcare reform in 2009, a series of measures have been implemented to expand coverage, strengthen primary care, and improve resource allocation. The chosen period captures the long-term demographic and health service transformations occurring within this reform framework. Thirdly, the relatively long timespan allows for the identification of both short-term fluctuations and long-term trends, such as accelerated population ageing, fertility decline, and structural adjustments in the health services system. By extending the dataset to 2022, the analysis incorporates the most recent demographic and health service developments, thereby enhancing the timeliness and policy relevance of the findings.
Data analysis
To evaluate the coordination between the population system and the health services system, this study established a comprehensive analytical framework. First, an indicator system was developed on the basis of existing literature and data availability, and was aligned with the theoretical framework proposed in this study. Second, the data of each indicator selected in each system were standardized and the entropy value method is used to determine the weight of each indicator; factor analysis was further conducted as a robustness check to verify the stability of the weighting scheme. Third, the coupling coordination degree (CCD) model was applied to assess the coupling and coordination level between the population system and the health services system. Finally, spatial dependence and the underlying driving mechanisms were assessed using global and local spatial autocorrelation analysis and further investigated through the Spatial Durbin Model (SDM).
Methodology
Selection of indicators
This study follows the principles of scientific validity, comprehensiveness, and data availability to construct an integrated evaluation indicator system for the population system and the health services system, as shown in Table 1. The weights of each indicator were determined using the entropy method.
Table 1.
Evaluation indicator system for the population and health services systems
| System | Sub-dimension | Indicators | Unit | Indicator direction | Average weight |
|---|---|---|---|---|---|
| Population system | Population size | Total population at year-end | 10,000 persons | + | 0.0998 |
| Natural population growth rate | ‰ | + | 0.0657 | ||
| Population structure | Proportion of population aged 0–14 years | % | + | 0.2188 | |
| Proportion of population aged 15–64 years | % | + | 0.1120 | ||
| Proportion of population aged ≥ 65 years | % | + | 0.1551 | ||
| Total dependency ratio | % | + | 0.1285 | ||
| Population density and distribution | Population density (per sq. km) | Persons/km² | + | 0.0998 | |
| Urban–rural population ratio | – | + | 0.1200 | ||
| Health services system | Health resource | Number of hospitals | piece | + | 0.0742 |
| Hospital beds per 1,000 population | Beds/1,000 persons | + | 0.0521 | ||
| Hospital health professionals per 1,000 population | Persons/1,000 | + | 0.0748 | ||
| Number of primary health care institutions | – | + | 0.0809 | ||
| Primary beds per 1,000 population | Beds/1,000 persons | + | 0.0664 | ||
| Primary health professionals per 1,000 population | Persons/1,000 | + | 0.1047 | ||
| Number of public health institutions | – | + | 0.0586 | ||
| Public health beds per 10,000 population | Beds/1,0000 persons | + | 0.0564 | ||
| Public health professionals per 1,000 population | Persons/1,000 | + | 0.0646 | ||
| Service provision and efficiency | Outpatient visits per physician per day (hospitals) | Visits/day | + | 0.0433 | |
| Inpatient bed-days per physician per day (hospitals) | Days/day | + | 0.0796 | ||
| Outpatient visits per physician per day (primary) | Visits/day | + | 0.0769 | ||
| Inpatient bed-days per physician per day (primary) | Days/day | + | 0.0855 | ||
| health management and coverage | Child health management rate (< 7 years) | % | + | 0.0368 | |
| Systematic maternal health management rate | % | + | 0.0441 |
The population system was assessed across three dimensions: population size, population structure, and population density and distribution. Population size captures both the overall stock and dynamic changes of the population; population structure is reflected in the proportions aged 0–14, 15–64, and ≥ 65 years, along with the total dependency ratio, which together indicate demographic composition and ageing pressures; population density and the urban–rural ratio represent spatial distribution and settlement patterns.
The health services system was evaluated across three dimensions: health resources, health service provision and efficiency, and health management and coverage. Health resources encompass the availability of medical institutions, bed capacity, and health personnel, constituting the essential material and human foundation of service delivery. Health service provision and efficiency reflect both the intensity of healthcare utilization and the effectiveness with which resources are transformed into services, thereby indicating the system’s operational capacity to meet population health needs. Health management and coverage embody the accessibility and coverage of essential health services, with child and maternal health management serving as representative indicators of the system’s preventive and long-term health protection functions.
Entropy weight method
The entropy method, was derived from the concept of information entropy in thermodynamics and evaluates the degree of variation in data to determine indicator weights [38]. Indicators that exhibit greater variability across regions and over time are assigned higher weights, reflecting their stronger influence on the comprehensive development level. Compared with subjective weighting methods, the entropy method reduces bias and enhances comparability, making it particularly suitable for constructing composite indices in large-scale spatiotemporal studies. In this study, the entropy method was applied to objectively assign weights to the indicators of the population and health services systems. The comprehensive development indices for the two systems were then calculated by weighted summation [39, 40]. The calculation steps are as follows:
(a) Data normalisation
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(b) Normalising the indicators/proportions
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(c) Calculating the information entropy of each indicator
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(d) Determining the weight of each indicator
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(e) Measuring the comprehensive development level of each subsystem
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Here, Xij and Xij’ are the raw and normalised values of indicator j in region i, respectively. Xmax and Xmin denote the maximum and minimum values of the indicator across all regions and years. Pij is the proportion of indicator j in region i. Ej and Wj represent the entropy value and weight of indicator j, respectively; and Ui indicates the comprehensive development index of the subsystem. The dataset is a balanced spatiotemporal panel covering 31 provinces in China from 2010 to 2022. The rightmost column of Table 1 reports the average weights of each indicator over the study period.
Coupling coordination degree model
The coupling coordination degree(CCD) integrates the development levels of both systems and reflects the extent of their interaction. It is widely applied to measure the coordinated development between multiple systems or subsystems [41]. Accordingly, this study adopts a two-system CCD model, expressed as follows:
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where C denotes the coupling degree. U1 and U2 represent the comprehensive evaluation values of the population system and the health services system, respectively. α1and α2 are the weights reflecting the contribution of each system. To reflect the theoretical symmetry between demand and supply, this study adopts an equal-weight specification in the baseline model (α1 = α2 = 1/2). From a governance perspective, the population system represents the demand side of health services, while the health services system constitutes the supply side; both are indispensable for achieving sustainable and equitable health development, and thus merit equal consideration. Nevertheless, to address the limitations of a purely normative assumption, factor analysis was employed to derive empirical system-level weights. The analysis extracted two factors with eigenvalues greater than 1, which together explained 76.3% of the total variance. Based on factor loadings, the empirical weights were estimated as α1 = 0.431 for the population system and α2 = 0.569 for the health services system. Robustness checks show that results under both weighting schemes yield broadly consistent conclusions, thereby supporting the appropriateness of the baseline equal-weight assumption while providing empirical validation.
T shows the comprehensive evaluation index of the two systems, and D represents the coupling coordination degree. A larger value of D indicates a higher overall development level of the subsystems and a stronger degree of coordination between them. Referring to previous studies [39, 40, 42], the types of coupling coordination development are classified as shown in Table 2.
Table 2.
Classification of coupling coordination degree
| Coordination type | Value range | Coordination rank |
|---|---|---|
| Dysfunctional recession | 0 ≤ D < 0.1 | Extremely dysfunctional recession |
| 0.1 ≤ D < 0.2 | Severely dysfunctional recession | |
| 0.2 ≤ D < 0.3 | Moderate dysregulation recession | |
| 0.3 ≤ D < 0.4 | Mild dysregulation recession | |
| Overcoordination stage | 0.4 ≤ D < 0.5 | On the verge of coupled coordination |
| 0.5 ≤ D < 0.6 | Barely coupled coordination | |
| Coordinated development | 0.6 ≤ D < 0.7 | Primary coupling coordination |
| 0.7 ≤ D < 0.8 | Intermediate coupling coordination | |
| 0.8 ≤ D < 0.9 | Good coupling coordination | |
| 0.9 ≤ D ≤ 1 | Quality coupling coordination |
Spatial autocorrelation
Global and local spatial autocorrelation analyses were applied to examine the spatial clustering characteristics of the CCD between the population and health services systems across China’s provincial-level regions. The spatial weight matrix was constructed using a contiguity-based approach, defining provinces with shared boundaries as neighbors to capture direct geographic interactions. Global spatial autocorrelation is measured by Moran’s I, which quantifies the degree of spatial aggregation or dispersion among spatial units [43]. The specific formula is as follows:
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where
,
. Zi denotes the CCD of region i, n is the number of spatial units, and Wij is the spatial weight. Moran’s I ranges from − 1 to 1: a value between 0 and 1 indicates positive spatial correlation, while a value between − 1 and 0 indicates negative spatial correlation.
Local spatial autocorrelation is measured by the local Moran’s I (or LISA), defined as:
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Based on LISA results, spatial relationships can be classified into five types: high–high, low–low, high–low, low–high, and insignificant clusters. A positive Ii indicates spatial clustering, where high (or low) values are surrounded by similar values. A negative Ii implies spatial mismatch, where a high value is surrounded by low values, or vice versa. In this study, local spatial autocorrelation is applied to reveal the spatial distribution patterns and heterogeneity of the CCD index.
Spatial Durbin Model
Given the potential spatial spillover effects in the CCD across provinces, this study adopts a spatial econometric approach. The commonly used spatial econometric models include the Spatial Lag Model (SLM), the Spatial Error Model (SEM), and The Spatial Durbin Model (SDM). Among them, the SDM is widely recognised as a foundational framework, as it captures spatial dependence in both the dependent and independent variable [44].
Model selection. To determine the appropriate model form, the Lagrange Multiplier (LM) test and the robust LM test, as well as the Likelihood Ratio (LR) and Wald tests, were conducted. Under the inverse-distance spatial weight matrix, the test statistics were all significant at the 1% level, rejecting the null hypothesis of no spatial effects and supporting the choice of the SDM over the SLM or SEM. In addition, the Hausman test indicated that the fixed-effects specification was preferred to the random-effects model. Therefore, the empirical analysis employs a two-way fixed-effects SDM.
Model specification. The SDM is formally expressed as follows:
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Where Dit denotes the CCD in province i at time t; C0 is the constant term; ρ is the spatial autoregressive coefficient of the dependent variable; Wij are elements of the row-standardised spatial weight matrix W; Xit is the vector of explanatory variables with coefficients β; θ indicates the coefficients of the spatially lagged explanatory variables, capturing their spillover effects; µi and λi denote province and year fixed effects, respectively; and εit is the error term.
Spatial weights. The spatial weight matrix W was specified as a row-standardised first-order contiguity (Rook) matrix with zero diagonal elements, in which provinces sharing a common border are considered neighbors. This specification is widely used in spatial econometric analysis as it captures direct geographic interactions across adjacent administrative units. Robustness was further assessed using alternative matrices, including a k-nearest neighbors (k-NN) specification.
Endogeneity and identification. To mitigate simultaneity (e.g., provinces with higher CCD may subsequently attract greater fiscal inputs or digital infrastructure upgrades), potentially endogenous covariates were lagged by one period in the baseline specification to mitigate reverse causality concerns.
Explanatory variables. Four principal explanatory variables were included to capture the institutional and structural determinants of CCD (see Table 3). Government health expenditure reflects the scale and intensity of public investment in health services [45, 46]. Health insurance coverage represents financial protection and access equity [47]. Digital infrastructure measures the availability and penetration of information technologies [48], and transport infrastructure reflects regional accessibility and connectivity [49]. Each of these variables was constructed as a composite index using the entropy-weight method, based on multiple sub-indicators in the China Health Statistical Yearbook and China Statistical Yearbook. By integrating diverse sub-indicators, the entropy-weight method provides a more balanced and representative measure than reliance on any single indicator.
Table 3.
Explanatory and control variables: description and measurement
| Variable | Indicators | Unit | Direction | Average weight |
|---|---|---|---|---|
| Explanatory variables | ||||
| Government health expenditure | Government health expenditure | 100 million CNY | + | 0.5181 |
| Health expenditure as % of GDP | % | + | 0.4818 | |
| Health insurance coverage | Number of insured persons | 10,000 persons | + | 0.6362 |
| Health insurance coverage rate | % | + | 0.3637 | |
| Digital infrastructure | Number of internet users | 10,000 persons | + | 0.4771 |
| Broadband access subscribers | 10,000 households | + | 0.5228 | |
| Transport infrastructure | Road density | km/ km2 | + | 0.4406 |
| Railway density | km/ km2 | + | 0.5593 | |
| Control variable | ||||
| Economic development | GDP per capita | CNY | + | – |
| Ageing level | Proportion of elderly population | % | + | – |
| Urbanisation rate | Proportion of urban population | % | + | – |
| Disposable income level | Per capita disposable income | CNY | + | – |
Note: Average weights were calculated using the entropy-weight method based on temporal and provincial variation
Control variables. To account for socio-economic background conditions, additional covariates were included: economic development, ageing rate, urbanisation rate, and disposable income level. Province and year fixed effects were also incorporated. All continuous variables were standardised prior to estimation to ensure comparability and numerical stability across specifications.
Result
Analysis of the comprehensive evaluation index and coupling coordination degree between the population and health services systems from 2010 to 2022
From 2010 to 2022, the comprehensive evaluation indices of China’s population system and health services system exhibited an overall upward trend. The population system index increased from 0.140 to 0.674, captured long-term shifts in population size, structure, and spatial distribution. The health services system index rose from 0.196 to 0.722, reflected continuous growth in health resources and service provision (Fig. 2a). Correspondingly, the coupling coordination degree (CCD) between the two systems advanced from 0.407 to 0.835, indicated a progressive enhancement in the coordination of population dynamics and health service development (Fig. 2b).
Fig. 2.

(a) Trends in the comprehensive development indices of the Population system and the Health services system, 2010–2022. (b) Trends in the coupling coordination degree (CCD) between the Population system and the Health services system, 2010–2022
At the regional level, both subsystems have shown steady improvement, though their development trajectories varied across regions (Fig. 3a and b). In the east, the CCD increased from 0.682 in 2010 to 0.885 in 2022, with both the population and health services indices remained at relatively high levels and advanced steadily. In the central region, the CCD rose from 0.484 to 0.754, with a pronounced gap between the two subsystems during 2010–2012, followed by gradual convergence in later years. In the west, the CCD grew from 0.474 to 0.699, with an initial gap between the two subsystems, had followed by steady growth and narrowing differences over time.
Fig. 3.

(a) Trends in the comprehensive development indices of the Population system (U₁) and the Health services system (U₂) across eastern, central, and western China, 2010–2022 (Regions follow the China Statistical Yearbook classification; values are region-level composites, not provincial averages.). (b) Trends in the coupling coordination degree (CCD) between the Population and Health services systems across eastern, central, and western China, 2010–2022
At the provincial level, CCD values ranged from 0.560 to 0.715 in 2010, with eastern coastal provinces concentrated at the upper end of the distribution (e.g., Shanghai at 0.715), while several inland provinces stayed closer to 0.56 (Fig. 4a). By 2016, the range shifted upward to 0.652–0.709, with most provinces clustered above 0.67 (Fig. 4b). In 2022, CCD values further increased to 0.680–0.752, with leading provinces such as Shanghai, Jiangsu, Zhejiang, and Beijing exceeding 0.72, while some western provinces remained below 0.70 (Fig. 4c).
Fig. 4.

Provincial variation in the coupling coordination degree (CCD) across China, (a) 2010, (b) 2016, and (c) 2022
Spatial autocorrelation analysis of the coupling coordination between population and health services system from 2010 to 2022
Global spatial autocorrelation of the coupling coordination degree (CCD) between the population and health service systems was assessed using Moran’s I. As reported in Table 4, the global Moran’s I values ranged from 0.184 to 0.238 during 2010–2022, with all values statistically significant. This reflects a stable and positive spatial autocorrelation, indicating persistent clustering and spatial spillover effects among provinces.
Table 4.
Global Moran’s I values for the coupling coordination of the Population and Health services systems, 2010–2022
| Year | Moran’s I | Sd(I) | Z | Year | Moran’s I | Sd(I) | Z |
|---|---|---|---|---|---|---|---|
| 2010 | 0.184* | 0.106 | 2.047 | 2017 | 0.251** | 0.103 | 2.757 |
| 2011 | 0.195** | 0.086 | 2.651 | 2018 | 0.268** | 0.117 | 2.573 |
| 2012 | 0.203** | 0.082 | 2.878 | 2019 | 0.273** | 0.114 | 2.684 |
| 2013 | 0.216** | 0.087 | 2.862 | 2020 | 0.262** | 0.108 | 2.731 |
| 2014 | 0.237** | 0.091 | 2.967 | 2021 | 0.254** | 0.109 | 2.633 |
| 2015 | 0.254** | 0.103 | 2.786 | 2022 | 0.238* | 0.120 | 2.258 |
| 2016 | 0.263** | 0.111 | 2.667 |
Note: * P < 0.05, ** P < 0.01, *** P < 0.001
To analyze the evolution of the spatial distribution of the coupling coordination degree (CCD) across provinces, the years 2010, 2016, and 2022 were selected as cross-sectional time points. The Local Indicators of Spatial Association (LISA) were applied to these years, and the spatial clustering patterns of CCD values for 31 provincial units in mainland China were presented in Figs. 5; Table 5.
Fig. 5.

Moran scatterplots of the coupling coordination degree (CCD) between the Population system and Health services system in China for the years 2010, 2016, and 2022
Table 5.
Provincial distribution of Local Moran’s I cluster types for the coupling coordination degree in China, 2010, 2016 and 2022
| Year | High–high (HH) | High–low (HL) | Low–high (LH) | Low–low (LL) | Not significant |
|---|---|---|---|---|---|
| 2010 | Beijing, Tianjin, Liaoning, Shandong, Shanghai, Fujian [6] | Hubei, Guangdong [2] | None | Xinjiang, Qinghai, Sichuan, Yunnan, Guangxi, Jiangxi [6] | Hebei, Shanxi, Inner Mongolia, Jilin, Heilongjiang, Jiangsu, Zhejiang, Anhui, Henan, Hunan, Chongqing, Guizhou, Tibet, Shaanxi, Gansu, Ningxia, Hainan [17] |
| 2016 | Beijing, Tianjin, Hebei, Shandong, Jiangsu, Shanghai, Zhejiang, Fujian [8] | Sichuan [1] | Liaoning [1] | Xinjiang, Tibet, Qinghai, Jilin, Heilongjiang [5] | Shanxi, Inner Mongolia, Henan, Anhui, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Guizhou, Yunnan, Shaanxi, Gansu, Ningxia [16] |
| 2022 | Tianjin, Hebei, Shanxi, Shandong, Henan, Hubei, Shanghai, Zhejiang [8] | Sichuan [1] | Liaoning, Anhui, Fujian [3] | Xinjiang, Tibet, Qinghai, Jilin, Heilongjiang [5] | Beijing, Inner Mongolia, Jiangsu, Jiangxi, Hunan, Guangdong, Guangxi, Hainan, Chongqing, Guizhou, Yunnan, Shaanxi, Gansu, Ningxia [14] |
Note: Values in parentheses denote the number of provincial-level regions classified within each Local Moran’s I cluster category. HH represents high-value regions surrounded by neighbouring high-value regions; HL represents high-value regions surrounded by neighbouring low-value regions; LH represents low-value regions surrounded by neighbouring high-value regions; and LL represents low-value regions surrounded by neighbouring low-value regions. ‘Not significant’ denotes regions in which local spatial autocorrelation was not statistically significant at the specified level. Taiwan, Hong Kong and Macao, China, were not included in the analysis because comparable data were unavailable
In 2010, the LISA results indicated that high–high (HH) clusters were concentrated in several eastern coastal and northern provinces, including Beijing, Tianjin, Liaoning, Shanghai, Fujian, and Shandong. These provinces, located in the Bohai Rim and the Yangtze River Delta, benefited from relatively strong economies, better governance capacity, and a closer alignment between demographic structures and healthcare resources. In contrast, low–low (LL) clusters were mainly distributed in central and western provinces such as Jiangxi, Guangxi, Sichuan, Yunnan, Qinghai, and Xinjiang, where economic constraints, demographic imbalances, and limited healthcare capacity corresponded with relatively low coordination levels.
By 2016, spatial clustering became more evident. HH clusters expanded to include Beijing, Tianjin, Hebei, additional provinces in the Yangtze River Delta such as Jiangsu and Zhejiang, as well as Fujian and Shandong. Liaoning appeared as a low–high (LH) outlier, exhibiting relatively low internal coordination but surrounded by provinces with higher values, while Sichuan emerged as a high–low (HL) outlier, showing higher internal coordination but neighboring provinces with lower levels. At the same time, Heilongjiang, Tibet, Qinghai, and Xinjiang formed LL clusters, indicating that relatively low coordination persisted in parts of the Northeast and the western regions.
By 2022, the HH clusters had shifted somewhat, now concentrated in Tianjin, Hebei, Zhejiang, Shandong, Henan, and Hubei. This indicates that, in addition to the eastern coastal provinces, some central provinces such as Henan and Hubei had joined the high-value clusters, reflecting the rising role of the Central Plains in population–health coordination. Liaoning, Fujian, and Anhui were identified as LH outliers, while Sichuan remained a HL outlier. LL clusters persisted in Tibet, Qinghai, and Xinjiang, and also included the northeastern provinces of Jilin and Heilongjiang. These regions continued to show relatively low coordination levels, likely influenced by a combination of geographic, economic, and demographic factors.
Factors influencing the coupling coordination between the population and health services system
Spatial econometric analysis was applied to investigate the driving factors of the CCD. To determine the appropriate econometric model specification, a series of diagnostic tests were performed, including LM, LR, Wald, and Hausman tests. The results rejected the null hypothesis of no spatial dependence, and both LR and Wald tests supported the SDM as the optimal specification. The Hausman test favored fixed effects, justifying the use of a two-way fixed effects SDM to account for spatial and temporal heterogeneity (Table 6).
Table 6.
Results of specification tests for spatial econometric models
| Specification Test | Test Statistic | P |
|---|---|---|
| Moran’s I | 137.426 | < 0.001 |
| LM-lag test | 15.136 | < 0.001 |
| LM-error test | 12.478 | < 0.001 |
| Robust LM-lag test | 10.112 | 0.006 |
| Robust LM-error test | 7.903 | 0.004 |
| LR_Spatial_lag | 82.17 | 0.002 |
| LR_Spatial_error | 96.44 | < 0.001 |
| Wald_Spatial_lag | 38.29 | < 0.001 |
| Wald_Spatial_error | 24.36 | 0.001 |
| Hausman text | 58.75 | < 0.001 |
In the baseline OLS model (Table 7), without accounting for spatial effects, government health expenditure (GHE) (β = 0.322, P < 0.01) and digital infrastructure (DI) (β = 0.281, P < 0.05) were positively associated with CCD. Health insurance coverage (HIC) (β = 0.102, P < 0.01) and transport infrastructure (TI) (β = 0.157, P < 0.05) also showed significant positive associations. In the SDM, these associations were stronger. GHE (β = 0.434, P < 0.01), DI (β = 0.503, P < 0.001), HIC (β = 0.149, P < 0.001), and TI (β = 0.325, P < 0.05) all remained statistically significant. The spatial autoregressive coefficient was significant (ρ = 0.493, P < 0.001), confirming spatial dependence and spillover effects across provinces. Robustness checks using a K-nearest neighbor (K = 4) weight matrix and a lagged SDM produced results consistent with those from the baseline SDM based on Rook’s contiguity.
Table 7.
Regression results of driving factors for the Coupling Coordination Degree (CCD) between population and health services systems: OLS and SDM Models
| Variable/Model | OLS | SDM(Rook) | SDM (KNN = 4) | SDM_LAG |
|---|---|---|---|---|
| GHE | 0.322**(0.110) | 0.434**(0.168) | 0.412**(0.160) | 0.276*(0.134) |
| HIC | 0.102**(0.039) | 0.149***(0.045) | 0.125**(0.048) | 0.127**(0.049) |
| DI | 0.281*(0.142) | 0.503***(0.151) | 0.578***(0.159) | 0.492**(0.173) |
| TI | 0.157*(0.072) | 0.325*(0.160) | 0.291*(0.145) | 0.302*(0.147) |
| ED | 0.094(0.070) | 0.115*(0.057) | 0.135**(0.052) | 0.168**(0.065) |
| AGE | -0.011(0.027) | -0.026(0.051) | -0.031(0.054) | -0.014(0.052) |
| UR | 0.028(0.031) | 0.035(0.243) | 0.046(0.251) | 0.029(0.239) |
| DIL | 0.154(0.141) | 0.171(0.194) | 0.252(0.189) | 0.248(0.191) |
| Constant | 0.563***(0.073) | 0.298***(0.090) | 0.301***(0.091) | 0.274**(0.105) |
| ρ(rho) | 0.493***(0.095) | 0.441***(0.110) | 0.488***(0.097) | |
| sigma2_e | 0.006 | 0.0018 | 0.003 | |
| R2 | 0.723 | 0.831 | 0.829 | 0.772 |
Notes: * P < 0.05; ** P < 0.01; *** P < 0.001; Standard errors in parentheses
To further assess spatial effects, the SDM estimates were decomposed into direct, indirect, and total effects. As shown in Table 8, GHE (total effect = 0.489, P < 0.01) and DI (total effect = 0.569, P < 0.001) were significantly associated with CCD, mainly through direct effects. TI also showed a significant total effect (β = 0.356, P < 0.05), primarily from the direct effect. HIC was significant as well (total effect = 0.168, P < 0.001). Notably, both DI (indirect effect = 0.084, P < 0.01) and GHE (indirect effect = 0.069, P < 0.05) displayed significant positive spillover effects, indicating that improvements in these areas can enhance coordination in neighbouring regions. By contrast, the indirect effects of TI and HIC were not statistically significant, suggesting their influence is mainly localised. Among the control variables, ED was positively associated with CCD (direct effect = 0.109; total effect = 0.131, P < 0.05), whereas AGE showed a negative direct effect that was not statistically significant. UR and DIL likewise did not show significant direct or indirect effects.
Table 8.
Impact decomposition of the Spatial Durbin Model with two-way fixed effects
| Variable | Direct Effect | Indirect Effect | Total Effect |
|---|---|---|---|
| GHE | 0.420**(0.162) | 0.069*(0.035) | 0.489**(0.166) |
| HIC | 0.142***(0.043) | 0.026(0.027) | 0.168***(0.051) |
| DI | 0.485***(0.147) | 0.084**(0.032) | 0.569***(0.150) |
| TI | 0.305*(0.155) | 0.051(0.033) | 0.356*(0.158) |
| ED | 0.109*(0.055) | 0.022(0.020) | 0.131*(0.059) |
| AGE | -0.024(0.052) | -0.005(0.013) | -0.029(0.054) |
| UR | 0.041(0.237) | 0.012(0.025) | 0.053(0.239) |
| DIL | 0.163(0.189) | 0.033(0.050) | 0.196(0.202) |
Notes: * P < 0.05; ** P < 0.01; *** P < 0.001. Standard errors are reported in parentheses. Estimates are derived from the partial impact decomposition of the SDM, employing a Rook contiguity spatial weight matrix and two-way fixed effects
Discussion
Coordinated development of the population and health services systems from a comprehensive perspective
Over the past decade, socio-economic development has exerted a notable influence on China’s population and health services systems. Between 2010 and 2022, the comprehensive development indices of both subsystems rose steadily, from relatively low to higher levels, suggesting gradual improvement in demographic dynamics and health system performance [50, 51].
On the population side, accelerated ageing, rapid urbanisation, and large-scale migration reshaped demographic patterns, resulting in more complex and diverse health service needs. Rising household incomes and growing health awareness further contributed to increasing expectations for equitable and high-quality care [52, 53]. On the supply side, government and societal investment expanded the coverage and quality of health services [50]. The number of medical institutions, bed capacity, and health personnel increased, while advances in technology, digitalisation, and infrastructure enhanced accessibility and system responsiveness [54, 55]. Collectively, these changes indicate that the health services system has become more capable of adapting to evolving population needs.
Taken together, the two systems demonstrate an interdependent and dynamically interactive relationship: demographic change shapes the scale and structure of demand, while improvements in resources and efficiency provide the capacity to respond. This bidirectional linkage highlights the strategic importance of maintaining demand–supply coordination in health governance.
Evolutionary trends and regional variations in the coupling coordination between the population and health services systems
From 2010 to 2022, the coupling coordination degree (CCD) rose steadily, moving from an initial stage of dysfunction towards higher-level coordination. This reflects not only stronger connections between demographic dynamics and service provision, but also progress in resource allocation and management. With a rising share of older adults, faster urbanisation, and intensified cross-regional mobility, demand for medical and public health services grew substantially. These shifts underscore the need for governments to anticipate health needs arising from demographic change and to ensure resources are allocated effectively.
Regionally, all areas improved but along distinct trajectories. The east sustained a relatively high level of coordination, supported by a more developed health system, stronger fiscal capacity, and substantial population inflows [56]. The economic dynamism of the eastern coastal provinces has attracted large numbers of migrants, with arrival of younger labour migrants both mitigated ageing pressures and boosted demand for high-quality services, thereby aligning demographic structure with provision capacity [57]. High population density and rapid urbanisation also fostered more intensive and efficient service delivery, accelerating the conversion of resources into services [58, 59]. By contrast, the central region initially faced a marked supply–demand gap, as ageing outpaced service expansion. This gap narrowed over time with migrant return, infrastructure improvements, and targeted policy support, reflecting a catch-up effect. In the western and parts of northeast, CCD levels remained lower, shaped by demographic imbalances. Persistent labour outflows aggravated “relative ageing,” with a shrinking younger population undermining demand-side balance and constraining the vitality of local health systems [60]. Under such conditions, even quantitative increases in resources could not fully offset demographic pressures. Overall, regional variation in CCD reflects not only disparities in supply but also the combined effects of population structure and mobility patterns. Addressing these challenges requires differentiated strategies, including improving resource efficiency in less-developed areas, fostering interprovincial cooperation to manage mobility-driven imbalances, and integrating demographic change into long-term health planning.
Spatial agglomeration and clustering patterns of coupling coordination degree
Between 2010 and 2022, the CCD between China’s population and health services systems showed significant spatial autocorrelation, with most provinces resembling their neighbours. This produced stable “high–high” and “low–low” clusters, alongside several outliers.
High–high clusters emerged in the eastern coastal and northern provinces, centred on the Yangtze River Delta (Shanghai, Jiangsu, Zhejiang), and the Beijing–Tianjin–Hebei region. Their evolution was driven not only by favourable resource endowments but also by institutional innovation and factor mobility. These provinces implemented hierarchical diagnosis and treatment, medical insurance payment reforms, and medical consortiums early on, demonstrating stronger health governance capacity [61–63]. For example, the “Medical Consortium Model” and diagnosis-related group payment piloted in Shanghai and Jiangsu were subsequently diffused to other eastern and some central provinces, which facilitated more efficient resource allocation and service delivery [61]. Meanwhile, infrastructure improvements, particularly the expansion of the high-speed rail network and the development of telemedicine, facilitated cross-regional flows of people and health services, aligning demographic change more closely with service provision [64]. Over time, these high-value clusters expanded into central provinces such as Henan and Hubei, reflecting both infrastructure-driven mobility and the diffusion of supportive policies. Initiatives such as the “Healthy Central Plains” strategy and targeted national investment in health infrastructure further strengthened regional collaboration and institutional spillovers [65]. In Henan, the development of regional medical centres, the upgrading of county-level medical centres and the expansion of smart healthcare services may have strengthened the responsiveness of the health services system to population needs [66]. In Hubei, high-level medical resources, particularly general and tertiary hospitals, are markedly concentrated in central Wuhan. Combined with policies promoting hierarchical care, medical consortia, remote consultation and improved transport accessibility, this concentration may have strengthened Wuhan’s regional service function and created favourable conditions for resource sharing and referral linkages within Hubei and neighbouring areas [67].
By contrast, western and some northeastern provinces remained in low-value clusters, forming relatively stable agglomerations at the lower end of coordination. This outcome reflects the combined effects of demographic pressures, weaker economic foundations, and mobility constraints. Provinces such as Xinjiang, Tibet, and Qinghai have experienced sustained youth outmigration and accelerated ageing, deepening structural imbalances. At the same time, fiscal limitations and geographic remoteness restricted the circulation of medical resources and populations, constraining the alleviation of supply–demand mismatches. The persistence of such patterns suggests a potential “lock-in” effect, highlighting the need for stronger regional cooperation and institutional innovation to improve coordination [63, 68].
Notably, some provinces exhibited spatial outlier patterns. Sichuan, for example, displayed a high–low (HL) configuration in 2016 and 2022, with relatively high intra-provincial coordination but lower levels in surrounding provinces. This pattern may be associated with Sichuan’s role as a medical hub in western China. Chengdu hosts a large share of tertiary hospitals and high-quality resources, supported by relatively strong public health governance, which has raised intra-provincial coordination [69]. Yet the province’s mountainous and basin-dominated terrain constrains transport links, and limited cross-regional flows of medical resources and populations have restricted external spillovers [70], resulting in a “high within, low around” spatial configuration. Conversely, northeastern provinces such as Liaoning occasionally presented a low–high (LH) outlier pattern in certain years. This may be linked to industrial restructuring, population outflows, and rapid ageing, which increased demand for long-term care while weakening fiscal capacity and service utilisation [71]. Although Shenyang and Dalian host major medical centres, the pull of higher-level facilities in the in the Beijing–Tianjin–Hebei region, together with convenient transport connections, has likely diverted part of the demand, weakening the alignment between local population needs and available services.
Driving factors and spatial spillovers for the coupling coordination degree between population and health services systems
This study, based on the spatial Durbin model (SDM), examined the key drivers and spatial effects of the CCD between the population and the health services systems. The results show that government health expenditure (GHE), health insurance coverage (HIC), digital infrastructure (DI), and transport infrastructure (TI) exert significant positive effects on CCD.
GHE, as a major channel of public investment, plays a fundamental role in fostering system coordination. Previous studies have noted that fiscal input affects health system performance and service accessibility through both both supply- and demand-side mechanisms: on the supply side, by financing health facilities, workforce training and public health systems [58]; and on the demand side, by supporting health programmes and medical assistance that alleviate the burden on vulnerable groups and improve service accessibility [72]. HIC also functions as an institutional safeguard. On the demand side, higher coverage reduces financial burdens, narrows disparities in healthcare utilisation across income groups, and improves access for older and vulnerable populations. On the supply side, payment and reimbursement arrangements guide providers to adjust services and resource allocation in line with population needs [73]. These institutional pathways provide a theoretical basis for understanding the positive association between GHE, HIC, and CCD. DI and TI also play crucial roles in strengthening coordination. Existing studies suggest that digitalisation enhances access to and efficiency of health services by optimising information flows and reducing transaction costs. On the demand side, telemedicine, internet-based hospitals, and electronic health records help residents in remote areas overcome geographical barriers, while on the supply side, big health data and smart platforms improve resource allocation and promote interregional collaboration [74]. Similarly, existing studies indicate that improved transport conditions reduce the time and travel costs of accessing healthcare, particularly in rural and remote areas, and facilitate the cross-regional movement of staff, equipment, and pharmaceuticals, thereby improving system efficiency [75, 76]. Collectively, these mechanisms provide useful insights into the positive associations between DI, TI, and CCD.
The SDM results also reveal significant spatial spillover effects. In particular, DI and GHE exhibited significant positive spillovers, suggesting that investments in information networks and public health financing can generate benefits beyond local boundaries by strengthening cross-regional information flows, connectivity, and institutional capacity. These effects can be understood through several channels, including the movement of health services resources, the diffusion of service demand driven by mobility, fiscal transfers extending governance capacity, and the integrative functions of digital and transport networks that transcend administrative borders. This suggests that fiscal transfers and regional health funds may help amplify the spillover effects of public investment, while cross-regional platforms and information-sharing mechanisms may foster digital coordination.
Finally, the SDM was applied to conduct standard deviation–based scenario simulations to quantify marginal effects. A one standard deviation increase in DI was associated with an average rise of 0.045 in CCD (5.6%), while TI increased it by 0.044 (5.4%). The effects of HIC and GHE were 0.029 (3.6%) and 0.025 (3.1%), respectively. These findings suggest that the four drivers play distinct roles in promoting system coordination, and that higher levels of coordination require integrating multidimensional policy instruments. Infrastructure and digital development improve accessibility and resource mobility, while fiscal input and health insurance provide institutional safeguards that strengthen stability and equity. Together, they constitute complementary foundations that enhance the alignment between population needs and health service provision and provide strategic support for equity, accessibility, and sustainability.
Limitation
This study has several limitations. Firstly, although the indicator system captures key dimensions of the population and health services systems, data availability constrained the breadth of measurement, particularly in relation to health management and service coverage. The indicators available for this dimension were nationally comparable and reflected important components of essential public health services, but did not fully capture broader areas such as chronic disease management, health management for older people, mental health services or service quality. Future studies should incorporate a wider range of indicators when consistent and comparable provincial-level data become available. Secondly, the entropy weight method used for weighting, while systematic, may obscure certain demographic characteristics such as age distribution and dependency ratios, which could substantially influence health system performance. Third, in calculating the CCD, equal weights were assigned to the two subsystems; although this choice is reasonable, the static assumption cannot capture potential variation in subsystem importance across regions or over time. Fourth, while lagging explanatory variables helps to mitigate reverse causality, it does not fully address potential endogeneity. Future research could explore instrumental variable methods or other causal inference techniques as data availability improves. Lastly, although the study identifies the main drivers of CCD, it does not further uncover the mechanisms through which these factors influence coordination, such as resource allocation, institutional arrangements, or behavioural incentives.
Conclusion
Based on the temporal evolution of indicators for China’s population and health services systems between 2010 and 2022, this study adopts the coupling coordination degree model to evaluate the degree of coupling coordination between the two systems at national, regional, and provincial scales. Overall, coordination progressed from a low to a medium–high level nationwide, with the east sustaining higher coordination, while the central and western regions gradually progressed from low to primary coordination. Spatial analysis confirmed significant dependence in provincial CCD, with patterns dominated by “high–high” clusters in the Yangtze River Delta and the Beijing–Tianjin–Hebei region that gradually extended into central provinces, and by persistent “low–low” clusters in west and north-east, alongside several outliers. The coordination is influenced by multiple factors and exhibits spatial spillovers. Government health expenditure, health insurance coverage, digital and transport infrastructure all had positive effects, with government health expenditure and digital development showing stronger cross-regional spillovers.
Overall, the coordinated development of the population and health services systems requires closer alignment between demographic dynamics and health service capacity. Given the regional variations identified, future policy design should adopt differentiated regional strategies. Eastern provinces could further translate their resource agglomeration advantages into wider regional spillover benefits by strengthening cross-provincial referral networks, regional medical consortia, interoperable digital health platforms, interprovincial information sharing and mutual recognition of examination results. Central provinces could consolidate their catch-up momentum by developing regional medical centres as service hubs, improving county-level medical capacity, strengthening primary care networks and referral coordination, and enhancing their capacity to absorb and further diffuse health resources across neighbouring areas. Resource planning in these provinces should also respond more closely to population return, urban agglomeration and ageing. Western provinces, as well as low-coordination areas in north-eastern China, could prioritise targeted fiscal transfers, workforce retention incentives, telemedicine, mobile health services, emergency transport networks and interprovincial counterpart assistance to address geographical barriers, population outflow, ageing pressures and limited local service capacity.
Acknowledgements
We would like to thank the study participants and collaborators.
Abbreviations
- AGE
Ageing rate
- CCD
Coupling coordination degree
- DI
Digital infrastructure
- DIL
Disposable income level
- ED
Economic development
- GHE
Government health expenditure
- HH
High-high cluster
- HIC
Health insurance coverage
- HL
High-low outlier
- LH
Low-high outlier
- LISA
Local indicators of spatial association
- LL
Low-low cluster
- OLS
Ordinary least squares
- SDM
Spatial Durbin Model
- TI
Transport infrastructure
- UR
Urbanisation rate
Author contributions
LL and LZ conceived the study. LL wrote the initial draft which was updated by RH, YX. LL, WR performed the statistical analyses. All authors have read and approved the manuscript.
Funding
This study was funded by the National Natural Science Foundation of China (Grant No: 72104073; 72474162). The funders did not participate in study design, data collection, analysis, interpretation of data and manuscript writing.
Data availability
No datasets were generated or analysed during the current study.
Declarations
Ethical approval
Not applicable.
Consent for publication
Not applicable.
Competing interests
The authors declare no competing interests.
Footnotes
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
References
- 1.GBD 2021 Fertility Collaborators. Global fertility in 204 countries and territories, 1950–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403(10440):2057–99. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Xiang Z, Wang H, Li H. Comorbidity risk and distribution characteristics of chronic diseases in the elderly population in China. BMC Public Health. 2024;24:360. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Wang W, Song J, Fan C, Li Q, Ma D, Yin W. Cross-sectional study of factors affecting the receipt of mental health education in older migrants in China. BMC Public Health. 2023;23:376. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.Emadi M, Delavari S, Bayati M. Global socioeconomic inequality in the burden of communicable and non-communicable diseases and injuries: an analysis on Global Burden of Disease Study 2019. BMC Public Health. 2021;21:688. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Vollset SE, Goren E, Yuan CW, et al. Fertility, mortality, migration, and population scenarios for 195 countries and territories, 2017–2100: a forecasting analysis for the Global Burden of Disease Study. Lancet. 2020;396(10258):1285–306. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Fang S, Liang H, Liang Y. Typologies of dependency, household characteristics, and disparity in formal and informal care use: analysis of community-dwelling long-term care insurance claimants in an urban municipality of China. Int J Equity Health. 2023;22:235. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Debie A, Nigusie A, Gedle D, Khatri RB, Assefa Y. Building a resilient health system for universal health coverage and health security: a systematic review. Glob Health Res Policy. 2024;9:2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 8.Cunningham R, Polomano R, Wood R, Aysola J. Health systems and health equity: Advancing the agenda. Nurs Outlook. 2022;70(6 Suppl):S66–76. [DOI] [PubMed] [Google Scholar]
- 9.Schoffer O, Schriefer D, Werblow A, Gottschalk A, Peschel P, Liang LA, Karmann A, Klug SJ. Modelling the effect of demographic change and healthcare infrastructure on the patient structure in German hospitals – a longitudinal national study based on official hospital statistics. BMC Health Serv Res. 2023;23:1081. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 10.Chen JT, Yang K, Zhu Y, Wu XW, et al. The impact of the scale and hierarchical structure of health human resources on the level of medical services-based on China’s four major economic regions. Int J Equity Health. 2024;23:166. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 11.Santana IR, Travassos C, Almeida C, Bousquat A. Need, demand, supply in health care: working definitions and their implications for defining access. Health Econ Policy Law. 2023;18(1):1–13. [DOI] [PubMed] [Google Scholar]
- 12.Pronk NP. An ecological framework for population health and well-being. Prog Cardiovasc Dis. 2025;90:13–21. [DOI] [PubMed] [Google Scholar]
- 13.Piquer-Martinez C, Lo Scalzo A, Otero-Garcia L, Ricciardi W. Theories, models and frameworks for health systems integration: a scoping review. Health Policy. 2024;141:104997. [DOI] [PubMed] [Google Scholar]
- 14.Vidoli F, Fusco E, D’Onofrio S, Vallati A. Health-care demand and supply at municipal level: evidence from Italy. Socio-Econ Plan Sci. 2022;84:101229. [Google Scholar]
- 15.Mirzoev T, Gritton J, Kane S, Lee JT, Martiniuk A, Mwisongo A, Raven J, Sheikh K, Ssengooba F, Gilson L. Theoretical foundations and mechanisms of health systems responsiveness: a realist synthesis. SSM – Health Syst. 2025;4:100061. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 16.Boniol M, Kunjumen T, Nair TS, Siyam A, Campbell J, Diallo K. The global health workforce stock and distribution in 2020 and 2030: a threat to equity and ‘universal’ health coverage? BMJ Glob Health. 2022;7(6):e009316. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 17.George J, Jack S, Gauld R, Colbourn T, Stokes T. Impact of health system governance on healthcare quality in low-income and middle-income countries: a scoping review. BMJ Open. 2023;13:e073669. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.Ma M, Shi L, Xie W, et al. Coupling coordination degree of healthcare resource supply, demand and elderly population change in China. Int J Equity Health. 2024;23:147. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 19.Gao L, Wang B, Yang X, et al. Can the organization of health resource integration be analyzed in terms of unmet demand for health services? A case study of elderly needs in Zhejiang Province, China. BMC Prim Care. 2022;23:288. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 20.Wang Y, Wang X, Ye X. Inequalities in unmet needs for healthcare services among middle-aged and older adults in China. J Aging Soc Policy. 2026;38(2):259–76. [DOI] [PubMed] [Google Scholar]
- 21.Monsef N, Suliman E, Ashkar E, Hussain HY. Healthcare services gap analysis: a supply capture and demand forecast modelling, Dubai 2018–2030. BMC Health Serv Res. 2023;23:468. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 22.Senderowicz L, Maloney N. Supply-side versus demand-side unmet need: implications for family planning programs. Popul Dev Rev. 2022;48(3):689–722. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 23.Weaver AK, Head JR, Gould CF, et al. Environmental factors influencing COVID-19 incidence and severity. Annu Rev Public Health. 2022;43:271–91. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 24.Saunders PJ, Middleton JD, Rudge G. Environmental public health tracking: a cost-effective system for characterizing the sources, distribution and public health impacts of environmental hazards. J Public Health (Oxf). 2017;39(3):506–13. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 25.Vinson DA, Werner AK. Examining select sociodemographic characteristics of sub-county geographies for public health surveillance. Popul Health Metr. 2024;22:29. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 26.George NC, Radman D, Zomahoun HT, et al. Linkages between health systems and communities for chronic care: a scoping review protocol. BMJ Open. 2022;12(8):e060430. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 27.Stadnick NA, Sadler E, Sandall J, et al. Comparative case studies in integrated care implementation from across the globe: a quest for action. BMC Health Serv Res. 2019;19:899. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 28.Chen L, Wang L, Zhang Y, Qian Z, Wang H, Xu Y, et al. The contributions of population distribution, healthcare resourcing, and transportation infrastructure to spatial accessibility of health care. INQUIRY. 2023;60:00469580221150201. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 29.Xu X, Han Z, Liang Q, Hu M, Chen Q, Fang W, et al. Spatial differences, dynamic evolution and influencing factors of the coupling and coordination relationship between health resources allocation and health service utilization in China. BMC Public Health. 2025;25:1773. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 30.Peng R, Huang J, Deng X. Spatiotemporal evolution and influencing factors of the allocation of social elderly care resources for the older adults in China. Int J Equity Health. 2023;22:222. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 31.Abimbola S, Negin J, Martiniuk AL, Jan S. Institutional analysis of health system governance. Health Policy Plan. 2017;32(9):1337–44. [DOI] [PubMed] [Google Scholar]
- 32.World Health Organization. Everybody’s business: strengthening health systems to improve health outcomes: WHO’s framework for action. Geneva: World Health Organization. 2007. Available from: https://apps.who.int/iris/handle/10665/43918.
- 33.Guyon A, Hancock T, Kirk M, MacDonald M, Neudorf C, Sutcliffe P, Talbot J, Watson-Creed G. The weakening of public health: A threat to population health and health care system sustainability. Can J Public Health. 2017;108(1):e1–6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 34.OECD. Rethinking health system performance assessment: a renewed framework. OECD Health Policy Studies. Paris: OECD Publishing. 2024. Available from: 10.1787/107182c8-en.
- 35.Shao H, Jin C, Xu J, Zhong Y, Xu B, et al. Supply-demand matching of medical services at a city level under the background of hierarchical diagnosis and treatment – based on Didi Chuxing Data in Haikou City. BMC Health Serv Res. 2022;22:354. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 36.National Health Commission of China. China Health Statistics Yearbook 2010–2021. Beijing: National Health Commission. 2022. Available from: http://www.nhc.gov.cn/mohwsbwstjxxzx/tjtjnj/new_list.shtml.
- 37.National Bureau of Statistics of China. China Statistical Yearbook 2010–2021. Beijing: National Bureau of Statistics. 2022. Available from: http://www.stats.gov.cn/tjsj/ndsj/.
- 38.Zhu Y, Tian D, Yan F. Effectiveness of entropy weight method in decision-making. Math Probl Eng. 2020;2020:3564835. [Google Scholar]
- 39.Li Y, Li Y, Zhou Y, et al. Investigation of a coupling model of coordination between urbanization and the environment. J Environ Manage. 2012;98:127–33. [DOI] [PubMed] [Google Scholar]
- 40.Liu N, Liu C, Xia Y, et al. Examining the coordination between urbanization and eco-environment using coupling and spatial analyses: a case study in China. Ecol Indic. 2018;93:1163–75. [Google Scholar]
- 41.Wang S, Kong W, Ren L, et al. Research on misuses and modification of the coupling coordination degree model in China. J Nat Resour. 2021;36(3):793–810. [Google Scholar]
- 42.Cheng X, Long R, Chen H, et al. Coupling coordination degree and spatial dynamic evolution of a regional green competitiveness system: a case study from China. Ecol Indic. 2019;104:489–500. [Google Scholar]
- 43.Anselin L, Getis A. Spatial statistical analysis and geographic information systems. Ann Reg Sci. 1992;26(1):19–33. [Google Scholar]
- 44.Beer C, Riedl A. Modelling spatial externalities in panel data: the Spatial Durbin Model revisited. Pap Reg Sci. 2012;91(2):299–319. [Google Scholar]
- 45.Xu H, Zhang X, Li Y. The temporal and spatial interpretation of China’s health financing: what do Chinese government do in new healthcare reform? Health Econ Rev. 2024;14:51. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 46.Luo S, Zhang J, Heffernan M. Forecast of total health expenditure on China’s ageing population: a system dynamics model. BMC Health Serv Res. 2024;24:1655. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 47.Lee D-C, Wang J, Shi L, et al. Health insurance coverage and access to care in China. BMC Health Serv Res. 2022;22:140. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 48.Jia H. Impact of digital infrastructure construction on migrants’ utilization of basic public health services in China. BMC Health Serv Res. 2024;24:761. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 49.Bu T, Tang D, Tang C, Liu Y. Does high-speed rail relieve income-related health inequalities? A quasi-natural experiment from China. J Transp Health. 2022;26:101409. [Google Scholar]
- 50.Yip W, Fu H, Chen AT, et al. Ten years of health-care reform in China: progress and gaps in universal health coverage. Lancet. 2019;394(10204):1192–204. [DOI] [PubMed] [Google Scholar]
- 51.Meng Q, Mills A, Wang L, et al. What can we learn from China’s health system reform? BMJ. 2019;365:l2349. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 52.Guo Y, Zhong W. How urbanization shapes rural ageing in China? Evidence from spatial Durbin and threshold regression models. Habitat Int. 2025;163:103487. [Google Scholar]
- 53.Wang Q, Liu S, Yang X, Gong C, Zhang W, Yang L, et al. Anticipated need, demand, and supply of doctors and beds in China: approaching a turning point. Discov Health Syst. 2025;4:8. [Google Scholar]
- 54.Wang Z, Dong L, Xing X, Liu Z, Zhou Y. Disparity in hospital beds’ allocation at the county level in China: an analysis based on a Health Resource Density Index (HRDI) model. BMC Health Serv Res. 2023;23:1293. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 55.Fu L, Wang R, Dong Y. The impact of the hierarchical medical system on medical resource allocation in China. Sci Rep. 2025;15(1):7561. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 56.Dong E, Xu J, Sun X, et al. Differences in regional distribution and inequality in health-resource allocation on institutions, beds, and workforce: a longitudinal study in China. Arch Public Health. 2021;79:78. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 57.Feng R, Huang J, Huang D. Comparison of the impact of different economic patterns on population inflows: evidence from China’s Guangdong, Jiangsu, and Zhejiang provinces. Sustainability. 2024;16(12):5176. [Google Scholar]
- 58.Zhu S, Liu J, Wang Z, Chen S. Study on regional disparities and influencing factors of public health service supply in China. BMC Health Serv Res. 2025;25:1172. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 59.Suo Z, Shao L, Lang Y. A study on the factors influencing the utilization of public health services by China’s migrant population based on the Shapley value method. BMC Public Health. 2023;23:2328. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 60.Dou H, Wang C, Cheng G, Lei X, Xu S. The vision of younger-seniors-based elderly care in rural China: based on population aging predictions from 2020 to 2050. Humanit Soc Sci Commun. 2025;12:669. [Google Scholar]
- 61.Lin K, Xiao Y, Zhang Q, Sun L, Liu F. The impact of an innovative payment method on medical expenditure, efficiency, and quality for inpatients with different types of medical insurance: evidence from a pilot city, China. Int J Equity Health. 2024;23:219. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 62.Fu L, Wang R, Dong Y. Policy texts and actions: quantitative evaluation of the hierarchical medical system policy in China based on the PMC-Index model. BMC Public Health. 2025;25:2358. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 63.Dai G, Li R, Ma S. Research on the equity of health resource allocation in TCM hospitals in China based on the Gini coefficient and agglomeration degree, 2009–2018. Int J Equity Health. 2022;21:145. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 64.Song CX, Li J, Gao X, Xu K, Chen H. Does high-speed rail opening affect the health care environment? Evidence from China. Front Public Health. 2021;9:708527. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 65.The CPC Henan Provincial Committee, Henan Provincial People’s Government. Healthy Central Plains 2030 Planning Outline. Zhengzhou: Henan Provincial Government. 2017. Available from: https://www.sport.gov.cn/gdnps/files/c25523877/25523909.pdf.
- 66.He X, Cui F, Lyu M, Sun D, Zhang X, Shi J, Zhang Y, Jiang S, Zhao J. Key factors influencing the operationalization and effectiveness of telemedicine services in Henan Province, China: Cross-sectional analysis. J Med Internet Res. 2024;26:e45020. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 67.Chen Q, Cheng J, Tu J. Analysing the global and local spatial associations of medical resources across Wuhan city using POI data. BMC Health Serv Res. 2023;23:96. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 68.Chen X, Chen Y, Qin B, He Q. Enhancing Health Equity in China: The Interplay of Public Health Infrastructure, Service Utilization, and Health Insurance. Sustainability. 2025;17(11):4785. [Google Scholar]
- 69.Liu X, Ye M. Medical service performance evaluation of tertiary general hospitals in Sichuan Province in China based on diagnosis-related groups. BMC Health Serv Res. 2025;25(1):563. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 70.Zhang N, Ning W, Xie T, Liu J, He R, Zhu B, Mao Y. Spatial disparities in access to healthcare professionals in Sichuan: evidence from county-level data. Healthcare. 2021;9(8):1053. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 71.Yang L, Zhao K, Fan Z. Exploring determinants of population ageing in Northeast China: from a socio-economic perspective. Int J Environ Res Public Health. 2019;16(21):4265. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 72.Wang L, Chen Y. Determinants of China’s health expenditure growth: based on Baumol’s cost disease theory. Int J Equity Health. 2021;20:213. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 73.Tang H, Li M, Liu LZ, Zhou Y, Liu X. Changing inequity in health service utilization and financial burden among patients with hypertension in China: evidence from CHARLS 2011–2018. Int J Equity Health. 2023;22:246. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 74.Zhong Y, Hahne J, Wang X, Wang X, Wu Y, Zhang X, Liu X. Telehealth care through internet hospitals in China: qualitative interview study of physicians’ views on access, expectations, and communication. J Med Internet Res. 2024;26:e47523. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 75.Bu T, Tang D, Zhang Z, Jiang C. Rural road improvement and individual health in China. J Asian Econ. 2025;98:101908. [Google Scholar]
- 76.Wu Y, Wang Q, Zheng F, Yu T, Wang Y, Fan S, Zhang X, Yang L. Effects of the implementation of transport-driven poverty alleviation policy on health care–seeking behavior and medical expenditure among older people in rural areas: quasi-experimental study. JMIR Public Health Surveill. 2023;9:e49603. [DOI] [PMC free article] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Data Availability Statement
No datasets were generated or analysed during the current study.












