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. 1988 Dec;78(12):1583–1584. doi: 10.2105/ajph.78.12.1583

Use of a leukocyte esterase dipstick to detect Chlamydia trachomatis and Neisseria gonorrhoeae urethritis in asymptomatic adolescent male detainees.

S F O'Brien 1, T A Bell 1, J A Farrow 1
PMCID: PMC1349742  PMID: 3189639

Abstract

We tested 91 asymptomatic adolescent male detainees in a short-stay detention facility in Seattle, Washington for the presence of leukocyte esterase in first-catch urine and for Chlamydia trachomatis and Neisseria gonorrhoeae infection. C. trachomatis was isolated from 10 subjects (11 per cent) and N. gonorrhoeae from five (5 per cent). Dipsticks detected leukocyte esterase in the urine of all 15 subjects with either infection and of 13 subjects with neither infection. Detection of leukocyte esterase was 100 per cent sensitive, 83 per cent specific, and 54 per cent predictive for the presence of either organism.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adger H., Shafer M. A., Sweet R. L., Schachter J. Screening for Chlamydia trachomatis and Neisseria gonorrhoeae in adolescent males: value of first-catch urine examination. Lancet. 1984 Oct 27;2(8409):944–945. doi: 10.1016/s0140-6736(84)91164-4. [DOI] [PubMed] [Google Scholar]
  2. Alexander-Rodriguez T., Vermund S. H. Gonorrhea and syphilis in incarcerated urban adolescents: prevalence and physical signs. Pediatrics. 1987 Oct;80(4):561–564. [PubMed] [Google Scholar]
  3. Chambers C. V., Shafer M. A., Adger H., Ohm-Smith M., Millstein S. G., Irwin C. E., Jr, Schachter J., Sweet R. Microflora of the urethra in adolescent boys: relationships to sexual activity and nongonococcal urethritis. J Pediatr. 1987 Feb;110(2):314–321. doi: 10.1016/s0022-3476(87)80180-4. [DOI] [PubMed] [Google Scholar]
  4. Feng W. C., Medeiros A. A., Murray E. S. Diagnosis of gonorrhea in male patients by culture of uncentrifuged first-voided urine. JAMA. 1977 Feb 28;237(9):896–897. [PubMed] [Google Scholar]
  5. Luciano A. A., Grubin L. Gonorrhea screening. Comparison of three techniques. JAMA. 1980 Feb 15;243(7):680–681. doi: 10.1001/jama.243.7.680. [DOI] [PubMed] [Google Scholar]
  6. Martin J. E., Armstrong J. H., Smith P. B. New system for cultivation of Neisseria gonorrhoeae. Appl Microbiol. 1974 Apr;27(4):802–805. doi: 10.1128/am.27.4.802-805.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Perera S. A., Jones C., Srikantha V., Ranawickrama W., Bhattacharyya M. N. Leucocyte esterase test as rapid screen for non-gonococcal urethritis. Genitourin Med. 1987 Dec;63(6):380–383. doi: 10.1136/sti.63.6.380. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sadof M. D., Woods E. R., Emans S. J. Dipstick leukocyte esterase activity in first-catch urine specimens. A useful screening test for detecting sexually transmitted disease in the adolescent male. JAMA. 1987 Oct 9;258(14):1932–1934. [PubMed] [Google Scholar]
  9. Shafer M. A., Prager V., Shalwitz J., Vaughan E., Moscicki B., Brown R., Wibbelsman C., Schachter J. Prevalence of urethral Chlamydia trachomatis and Neisseria gonorrhoeae among asymptomatic, sexually active adolescent boys. J Infect Dis. 1987 Jul;156(1):223–224. doi: 10.1093/infdis/156.1.223. [DOI] [PubMed] [Google Scholar]
  10. Stamm W. E., Harrison H. R., Alexander E. R., Cles L. D., Spence M. R., Quinn T. C. Diagnosis of Chlamydia trachomatis infections by direct immunofluorescence staining of genital secretions. A multicenter trial. Ann Intern Med. 1984 Nov;101(5):638–641. doi: 10.7326/0003-4819-101-5-638. [DOI] [PubMed] [Google Scholar]
  11. Stamm W. E., Tam M., Koester M., Cles L. Detection of Chlamydia trachomatis inclusions in Mccoy cell cultures with fluorescein-conjugated monoclonal antibodies. J Clin Microbiol. 1983 Apr;17(4):666–668. doi: 10.1128/jcm.17.4.666-668.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Veeravahu M., Smyth R. W., Clay J. C. Detection of leukocyte esterase in urine: a new screening test for nongonococcal urethritis compared with two microscopic methods. Sex Transm Dis. 1987 Jul-Sep;14(3):180–184. [PubMed] [Google Scholar]

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