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. 1989 Nov;79(11):1528–1530. doi: 10.2105/ajph.79.11.1528

Human cryptosporidiosis associated with an epizootic in calves.

J S Reif 1, L Wimmer 1, J A Smith 1, D A Dargatz 1, J M Cheney 1
PMCID: PMC1349807  PMID: 2817166

Abstract

An outbreak of human cryptosporidiosis occurred among previously healthy persons in a veterinary medical teaching hospital. Human illness began after admission of calves from a farm which had been experiencing an epizootic of neonatal diarrhea due to Cryptosporidium. The clinical syndrome in humans was characterized by watery diarrhea, abdominal cramping, flatulence, and headache. Cryptosporidiosis was confirmed by zinc sulfate flotation of fecal specimens in four persons, three of whom had been responsible for the care and treatment of infected calves. A fourth patient had washed her husband's soiled clothing and appeared to have been infected indirectly through fomite contamination. Among 112 persons surveyed, 26 (23.2 percent) had a diarrheal illness during the outbreak and nine met the case definition of a diarrheal illness lasting at least three days. These persons were more likely to have had contact with a calf with diarrhea than were 52 referents who did not become ill during the outbreak.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alpert G., Bell L. M., Kirkpatrick C. E., Budnick L. D., Campos J. M., Friedman H. M., Plotkin S. A. Outbreak of cryptosporidiosis in a day-care center. Pediatrics. 1986 Feb;77(2):152–157. [PubMed] [Google Scholar]
  2. Anderson B. C., Donndelinger T., Wilkins R. M., Smith J. Cryptosporidiosis in a veterinary student. J Am Vet Med Assoc. 1982 Feb 15;180(4):408–409. [PubMed] [Google Scholar]
  3. Anderson B. C., Hall R. F. Cryptosporidial infection in Idaho dairy calves. J Am Vet Med Assoc. 1982 Sep 1;181(5):484–485. [PubMed] [Google Scholar]
  4. Anderson B. C. Patterns of shedding of cryptosporidial oocysts in Idaho calves. J Am Vet Med Assoc. 1981 May 1;178(9):982–984. [PubMed] [Google Scholar]
  5. Current W. L., Reese N. C., Ernst J. V., Bailey W. S., Heyman M. B., Weinstein W. M. Human cryptosporidiosis in immunocompetent and immunodeficient persons. Studies of an outbreak and experimental transmission. N Engl J Med. 1983 May 26;308(21):1252–1257. doi: 10.1056/NEJM198305263082102. [DOI] [PubMed] [Google Scholar]
  6. D'Antonio R. G., Winn R. E., Taylor J. P., Gustafson T. L., Current W. L., Rhodes M. M., Gary G. W., Jr, Zajac R. A. A waterborne outbreak of cryptosporidiosis in normal hosts. Ann Intern Med. 1985 Dec;103(6 ):886–888. doi: 10.7326/0003-4819-103-6-886. [DOI] [PubMed] [Google Scholar]
  7. Gallaher M. M., Herndon J. L., Nims L. J., Sterling C. R., Grabowski D. J., Hull H. F. Cryptosporidiosis and surface water. Am J Public Health. 1989 Jan;79(1):39–42. doi: 10.2105/ajph.79.1.39. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Holley H. P., Jr, Dover C. Cryptosporidium: a common cause of parasitic diarrhea in otherwise healthy individuals. J Infect Dis. 1986 Feb;153(2):365–368. doi: 10.1093/infdis/153.2.365. [DOI] [PubMed] [Google Scholar]
  9. Janoff E. N., Reller L. B. Cryptosporidium species, a protean protozoan. J Clin Microbiol. 1987 Jun;25(6):967–975. doi: 10.1128/jcm.25.6.967-975.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Jokipii L., Pohjola S., Jokipii A. M. Cryptosporidiosis associated with traveling and giardiasis. Gastroenterology. 1985 Oct;89(4):838–842. doi: 10.1016/0016-5085(85)90581-5. [DOI] [PubMed] [Google Scholar]
  11. Jokipii L., Pohjola S., Jokipii A. M. Cryptosporidium: a frequent finding in patients with gastrointestinal symptoms. Lancet. 1983 Aug 13;2(8346):358–361. doi: 10.1016/s0140-6736(83)90341-0. [DOI] [PubMed] [Google Scholar]
  12. Levine J. F., Levy M. G., Walker R. L., Crittenden S. Cryptosporidiosis in veterinary students. J Am Vet Med Assoc. 1988 Dec 1;193(11):1413–1414. [PubMed] [Google Scholar]
  13. MANTEL N., HAENSZEL W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959 Apr;22(4):719–748. [PubMed] [Google Scholar]
  14. Meisel J. L., Perera D. R., Meligro C., Rubin C. E. Overwhelming watery diarrhea associated with a cryptosporidium in an immunosuppressed patient. Gastroenterology. 1976 Jun;70(6):1156–1160. [PubMed] [Google Scholar]
  15. Navin T. R., Juranek D. D. Cryptosporidiosis: clinical, epidemiologic, and parasitologic review. Rev Infect Dis. 1984 May-Jun;6(3):313–327. doi: 10.1093/clinids/6.3.313. [DOI] [PubMed] [Google Scholar]
  16. Nime F. A., Burek J. D., Page D. L., Holscher M. A., Yardley J. H. Acute enterocolitis in a human being infected with the protozoan Cryptosporidium. Gastroenterology. 1976 Apr;70(4):592–598. [PubMed] [Google Scholar]
  17. Pohjola S., Oksanen H., Jokipii L., Jokipii A. M. Outbreak of cryptosporidiosis among veterinary students. Scand J Infect Dis. 1986;18(2):173–178. doi: 10.3109/00365548609032325. [DOI] [PubMed] [Google Scholar]
  18. Rahaman A. S., Sanyal S. C., Al-Mahmud K. A., Sobhan A., Hossain K. S., Anderson B. C. Cryptosporidiosis in calves and their handlers in Bangladesh. Lancet. 1984 Jul 28;2(8396):221–221. doi: 10.1016/s0140-6736(84)90501-4. [DOI] [PubMed] [Google Scholar]
  19. Reese N. C., Current W. L., Ernst J. V., Bailey W. S. Cryptosporidiosis of man and calf: a case report and results of experimental infections in mice and rats. Am J Trop Med Hyg. 1982 Mar;31(2):226–229. doi: 10.4269/ajtmh.1982.31.226. [DOI] [PubMed] [Google Scholar]
  20. Soave R., Armstrong D. Cryptosporidium and cryptosporidiosis. Rev Infect Dis. 1986 Nov-Dec;8(6):1012–1023. doi: 10.1093/clinids/8.6.1012. [DOI] [PubMed] [Google Scholar]
  21. Tzipori S., Smith M., Birch C., Barnes G., Bishop R. Cryptosporidiosis in hospital patients with gastroenteritis. Am J Trop Med Hyg. 1983 Sep;32(5):931–934. doi: 10.4269/ajtmh.1983.32.931. [DOI] [PubMed] [Google Scholar]
  22. Wolfson J. S., Richter J. M., Waldron M. A., Weber D. J., McCarthy D. M., Hopkins C. C. Cryptosporidiosis in immunocompetent patients. N Engl J Med. 1985 May 16;312(20):1278–1282. doi: 10.1056/NEJM198505163122002. [DOI] [PubMed] [Google Scholar]

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