Abstract
1. Longitudinal tension was measured in isolated segments (approximately 20 mm in length and 2 mm in diameter) of bovine mesenteric lymphatic vessels.
2. Seventeen out of thirty-nine vessels showed regular spontaneous rhythmic contractions, the most common frequency being about 2/min.
3. The strength of each contraction was related to the duration of the preceding pause, a longer pause being associated with a stronger contraction.
4. Noradrenaline increased the frequency and decreased the amplitude of the contractions. This effect was abolished by α-receptor blockade with phentolamine.
5. Isoprenaline slowed the frequency of the contractions. This effect was abolished by β-receptor blockade with propranolol.
6. Acetylcholine had little effect on the rate of spontaneous contractions.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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