Abstract
We evaluated the diagnostic performance of 15 clinical case definitions for pertussis in 233 patients who developed acute respiratory illness during community outbreaks in Wisconsin and Delaware. Using results from culture (Regan-Lowe media) and serology (Ig-class-specific ELISA) as diagnostic standards, cough for greater than or equal to 14 days was both sensitive (84 per cent-92 per cent) and specific (63 percent-90 per cent) in identifying patients with pertussis. This definition may be useful in monitoring pertussis outbreaks and for investigating contacts of culture-positive cases.
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- Bass J. W. Erythromycin for treatment and prevention of pertussis. Pediatr Infect Dis. 1986 Jan-Feb;5(1):154–157. doi: 10.1097/00006454-198601000-00051. [DOI] [PubMed] [Google Scholar]
- Burstyn D. G., Baraff L. J., Peppler M. S., Leake R. D., St Geme J., Jr, Manclark C. R. Serological response to filamentous hemagglutinin and lymphocytosis-promoting toxin of Bordetella pertussis. Infect Immun. 1983 Sep;41(3):1150–1156. doi: 10.1128/iai.41.3.1150-1156.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Onorato I. M., Wassilak S. G. Laboratory diagnosis of pertussis: the state of the art. Pediatr Infect Dis J. 1987 Feb;6(2):145–151. doi: 10.1097/00006454-198702000-00002. [DOI] [PubMed] [Google Scholar]
- Regan J., Lowe F. Enrichment medium for the isolation of Bordetella. J Clin Microbiol. 1977 Sep;6(3):303–309. doi: 10.1128/jcm.6.3.303-309.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sacks J. J. Utilization of case definitions and laboratory reporting in the surveillance of notifiable communicable diseases in the United States. Am J Public Health. 1985 Dec;75(12):1420–1422. doi: 10.2105/ajph.75.12.1420. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sotomayor J., Weiner L. B., McMillan J. A. Inaccurate diagnosis in infants with pertussis. An eight-year experience. Am J Dis Child. 1985 Jul;139(7):724–727. doi: 10.1001/archpedi.1985.02140090086039. [DOI] [PubMed] [Google Scholar]
- Steketee R. W., Burstyn D. G., Wassilak S. G., Adkins W. N., Jr, Polyak M. B., Davis J. P., Manclark C. R. A comparison of laboratory and clinical methods for diagnosing pertussis in an outbreak in a facility for the developmentally disabled. J Infect Dis. 1988 Mar;157(3):441–449. doi: 10.1093/infdis/157.3.441. [DOI] [PubMed] [Google Scholar]
- Wasson J. H., Sox H. C., Neff R. K., Goldman L. Clinical prediction rules. Applications and methodological standards. N Engl J Med. 1985 Sep 26;313(13):793–799. doi: 10.1056/NEJM198509263131306. [DOI] [PubMed] [Google Scholar]