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Inset shows representative INa traces recorded before and after acute exposure to different concentrations of LiCl. In these experiments, maximal INa was elicited with 50-ms repetitive pulses to −30 mV from a holding potential of −120 mV. An IC50 for INa block by LiCl was generated: 6.8±0.4 μmol/L with a Hill coefficient of 0.86.
