Abstract
1. Complex unencapsulated nerve endings (right atrial receptors) have previously been found in the endocardium of the right atrial appendage and the junction between the superior vena cava and the right atrium.
2. Distension of balloons located in the right atrial appendage and at the junction between the superior vena cava and the right atrium resulted in an increase in urine flow. This diuresis was accompanied by a small increase in the excretion of sodium.
3. Cooling the right cervical vagus caused a reduction in the response to distension of the right atrial appendage.
4. It is concluded that stimulation of right atrial receptors by the distension of balloons located in the right atrial appendage and at the junction between the right atrium and the superior vena cava results in a reflex increase in urine flow.
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Selected References
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- Brennan L. A., Jr, Malvin R. L., Jochim K. E., Roberts D. E. Influence of right and left atrial receptors on plasma concentrations of ADH and renin. Am J Physiol. 1971 Jul;221(1):273–278. doi: 10.1152/ajplegacy.1971.221.1.273. [DOI] [PubMed] [Google Scholar]
- HENRY J. P., PEARCE J. W. The possible role of cardiac atrial stretch receptors in the induction of changes in urine flow. J Physiol. 1956 Mar 28;131(3):572–585. doi: 10.1113/jphysiol.1956.sp005483. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HOLMES R. L. Structures in the atrial endocardium of the dog which stain with methylene blue, and the effects of unilateral vagotomy. J Anat. 1957 Apr;91(2):259–266. [PMC free article] [PubMed] [Google Scholar]
- Kappagoda C. T., Linden R. J., Snow H. M. A reflex increase in heart rate from distension of the junction between the superior vena cava and the right atrium. J Physiol. 1972 Jan;220(1):177–197. doi: 10.1113/jphysiol.1972.sp009700. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kappagoda C. T., Linden R. J., Snow H. M. Distension of the right atrium and urine flow in the dog. J Physiol. 1973 Feb;229(1):26P–27P. [PubMed] [Google Scholar]
- Kappagoda C. T., Linden R. J., Snow H. M. The effect of distending the atrial appendages on urine flow in the dog. J Physiol. 1972 Dec;227(1):233–242. doi: 10.1113/jphysiol.1972.sp010029. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kappagoda C. T., Linden R. J., Snow H. M. The effect of stretching the superior vena caval-right atrial junction on right atrial receptors in the dog. J Physiol. 1972 Dec;227(3):875–887. doi: 10.1113/jphysiol.1972.sp010063. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEDSOME J. R., LINDEN R. J. A REFLEX INCREASE IN HEART RATE FROM DISTENSION OF THE PULMONARY-VEIN-ATRIAL JUNCTIONS. J Physiol. 1964 Apr;170:456–473. doi: 10.1113/jphysiol.1964.sp007343. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEDSOME J. R., LINDEN R. J., O'CONNOR W. J. The mechanisms by which distension of the left atrium produces diuresis in anaesthetized dogs. J Physiol. 1961 Nov;159:87–100. doi: 10.1113/jphysiol.1961.sp006794. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ledsome J. R., Linden R. J. The role of left atrial receptors in th diuretic response to left atrial distension. J Physiol. 1968 Sep;198(2):487–503. doi: 10.1113/jphysiol.1968.sp008619. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Linden R. J. Function of cardiac receptors. Circulation. 1973 Sep;48(3):463–480. doi: 10.1161/01.cir.48.3.463. [DOI] [PubMed] [Google Scholar]
- Purves M. J. The respiratory response of the new-born lamb to inhaled CO-2 with and without accompanying hypoxia. J Physiol. 1966 Jul;185(1):78–94. doi: 10.1113/jphysiol.1966.sp007973. [DOI] [PMC free article] [PubMed] [Google Scholar]