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. 1974 Jan;236(2):403–412. doi: 10.1113/jphysiol.1974.sp010442

The effect of antidiuretic hormone on human sweating

Judith A Allen, I C Roddie
PMCID: PMC1350809  PMID: 16992442

Abstract

1. Changes in insensible perspiration and sweating were followed in normal subjects by continuously monitoring total body weight loss in environmental temperatures of 18, 29 and 37° C.

2. Pharmacological doses of ADH had no effect on cutaneous water loss at 18° C.

3. Pharmacological doses of ADH are capable of increasing the rate of cutaneous water loss in human subjects who are close to or above the thermal sweating threshold.

4. Physiological doses of ADH had no effect on cutaneous water loss in either cool or hot environments.

5. At normal rates of secretion in the body, ADH probably does not influence human sweat secretion.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allen J. A., Grimley J. F., Roddie I. C. A body balance to measure sweat rates in man. Biomed Eng. 1971 Oct;6(10):468–471. [PubMed] [Google Scholar]
  2. Allen J. A., Jenkinson D. J., Roddie I. C. The effect of -adrenoceptor blockade on human sweating. Br J Pharmacol. 1973 Mar;47(3):487–497. doi: 10.1111/j.1476-5381.1973.tb08180.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Barraclough M. A., Jones N. F. The effect of vasopressin on the reabsorption of sodium, potassium and urea by the renal tubules in man. Clin Sci. 1970 Oct;39(4):517–527. doi: 10.1042/cs0390517. [DOI] [PubMed] [Google Scholar]
  4. Ellis R. A. Fine structure of the myoepithelium of the eccrine sweat glands of man. J Cell Biol. 1965 Dec;27(3):551–563. doi: 10.1083/jcb.27.3.551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. FUHRMAN F. A., USSING H. H. A characteristic response of the isolated frog skin potential to neurohypophysial principles and its relation to the transport of sodium and water. J Cell Physiol. 1951 Aug;38(1):109–130. doi: 10.1002/jcp.1030380109. [DOI] [PubMed] [Google Scholar]
  6. Fasciolo J. C., Totel G. L., Johnson R. E. Antidiuretic hormone and human eccrine sweating. J Appl Physiol. 1969 Sep;27(3):303–307. doi: 10.1152/jappl.1969.27.3.303. [DOI] [PubMed] [Google Scholar]
  7. HANKISS J. Effect of antidiuretic hormone on sweating as a proof of its extrarenal action. Am J Med Sci. 1959 Oct;238:452–455. doi: 10.1097/00000441-195910000-00008. [DOI] [PubMed] [Google Scholar]
  8. KOEFOED-JOHNSEN V., USSING H. H. The contributions of diffusion and flow to the passage of D2O through living membranes; effect of neurohypophyseal hormone on isolated anuran skin. Acta Physiol Scand. 1953 Mar 31;28(1):60–76. doi: 10.1111/j.1748-1716.1953.tb00959.x. [DOI] [PubMed] [Google Scholar]
  9. LAUSON H. D. The problem of estimating the rate of secretion of antidiuretic hormone in man. Am J Med. 1951 Aug;11(2):135–156. doi: 10.1016/0002-9343(51)90100-3. [DOI] [PubMed] [Google Scholar]
  10. LINZELL J. L. Some observations on the contractile tissue of the mammary glands. J Physiol. 1955 Nov 28;130(2):257–267. doi: 10.1113/jphysiol.1955.sp005408. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. MASES P., FALET R., JOLY R., HOUDAS Y. [Action of antidiuretic hormones on the elimination of cutaneous water]. C R Seances Soc Biol Fil. 1962;156:73–75. [PubMed] [Google Scholar]
  12. PEARCY M., ROBINSON S., MILLER D. I., THOMAS J. T., Jr, DEBROTA J. Effects of dehydration, salt depletion and pitressin on sweat rate and urine flow. J Appl Physiol. 1956 May;8(6):621–626. doi: 10.1152/jappl.1956.8.6.621. [DOI] [PubMed] [Google Scholar]
  13. RATNER A. C., DOBSON R. L. THE EFFECT OF ANTIDIURETIC HORMONE ON SWEATING. J Invest Dermatol. 1964 Nov;43:379–381. doi: 10.1038/jid.1964.168. [DOI] [PubMed] [Google Scholar]
  14. Schlein E. M., Spooner G. R., Day C., Pickering M., Cade R. Extrarenal water loss and antidiuretic hormone. J Appl Physiol. 1971 Oct;31(4):569–572. doi: 10.1152/jappl.1971.31.4.569. [DOI] [PubMed] [Google Scholar]
  15. Senay L. C., Jr, Van Beaumont W. Antidiuretic hormone and evaporative weight loss during heat stress. Pflugers Arch. 1969;312(3):82–90. doi: 10.1007/BF00588533. [DOI] [PubMed] [Google Scholar]

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