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. 1982 Jan;195(1):110–113. doi: 10.1097/00000658-198201001-00016

A simple method of orthotopic liver transplantation in dogs.

M Monden, R H Barters, J G Fortner
PMCID: PMC1352411  PMID: 7034657

Abstract

Orthotopic liver transplantations were performed by one team in 18 dogs using a cuff method to anastomose the portal vein, the suprahepatic vena cava and the infrahepatic vena cava without external or internal shunts. Total and warm ischemic times of donor liver averaged 124 and 32 minutes, respectively. The average occlusion time of the portal vein and the infrahepatic vena cava were 9.7 and 13.9 minutes, respectively. During this time, uncontrolled hypotension, petechiae or hemorrhagic enterogastritis did not develop. Sixteen of 18 dogs survived more than five days, and five dogs lived more than three weeks. The cause of death was not related to the cuff method in any instance. This approach proved to be a technically simple and satisfactory procedure.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bergan J., Teixeira E., Yu H., Clarke W., Coburn M. Hyperkalemia accompanying canine portal venous occlusion. Surgery. 1968 Sep;64(3):629–633. [PubMed] [Google Scholar]
  2. Cooperman A. M., Woods J. E., McIlrath D. C. Simplified method of canine orthotopic hepatic transplantation. Am J Surg. 1971 Dec;122(6):797–801. doi: 10.1016/0002-9610(71)90449-1. [DOI] [PubMed] [Google Scholar]
  3. GOODRICH E. O., Jr, WELCH H. F., NELSON J. A., BEECHER T. S., WELCH C. S. Homotransplantation of the canine liver. Surgery. 1956 Feb;39(2):244–251. [PubMed] [Google Scholar]
  4. Kamada N., Calne R. Y. Orthotopic liver transplantation in the rat. Technique using cuff for portal vein anastomosis and biliary drainage. Transplantation. 1979 Jul;28(1):47–50. [PubMed] [Google Scholar]
  5. Kuster G., Dawson B., Shorter R. G., Hallenbeck G. A. One stage allogeneic transplantation of the liver and hepatectomy in dogs. Surg Gynecol Obstet. 1969 Sep;129(3):565–575. [PubMed] [Google Scholar]
  6. MOORE F. D., SMITH L. L., BURNAP T. K., DALLENBACH F. D., DAMMIN G. J., GRUBER U. F., SHOEMAKER W. C., STEENBURG R. W., BALL M. R., BELKO J. S. One-stage homotransplantation of the liver following total hepatectomy in dogs. Transplant Bull. 1959 Jan;6(1):103–107. doi: 10.1097/00006534-195901000-00041. [DOI] [PubMed] [Google Scholar]
  7. MOORE F. D., WHEELE H. B., DEMISSIANOS H. V., SMITH L. L., BALANKURA O., ABEL K., GREENBERG J. B., DAMMIN G. J. Experimental whole-organ transplantation of the liver and of the spleen. Ann Surg. 1960 Sep;152:374–387. [PMC free article] [PubMed] [Google Scholar]
  8. Miyata M., Fischer J. H., Fuhs M., Isselhard W., Kasai Y. A simple method for orthotopic liver transplantation in the rat. Cuff technique for three vascular anastomoses. Transplantation. 1980 Nov;30(5):335–338. doi: 10.1097/00007890-198011000-00005. [DOI] [PubMed] [Google Scholar]
  9. TANTURI C., MEJIA R. H., CANEPA J. F., GOMEZ O. T. Electrocardiographic and humoral changes in transient occlusion of the portal vein in the dog. Surg Gynecol Obstet. 1960 May;110:537–540. [PubMed] [Google Scholar]
  10. Terblanche J., Peacock J. H., Bowes J., Hobbs K. E. The technique of orthotopic liver homotransplantation in the pig. J Surg Res. 1968 Apr;8(4):151–160. doi: 10.1016/0022-4804(68)90077-2. [DOI] [PubMed] [Google Scholar]
  11. Uchida H., Yokota K., Akiyama N., Masaki Y., Aso K., Okubo M., Okudaira M., Kato M., Kashiwagi N. Effectiveness of a new drug, bredinin, on canine kidney allotransplant survival. Transplant Proc. 1979 Mar;11(1):865–870. [PubMed] [Google Scholar]

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