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. 1982 Sep;196(3):371–378. doi: 10.1097/00000658-198209000-00017

Simple mastectomy and axillary node sampling (pectoral node biopsy) in the management of primary breast cancer.

A P Forrest, H J Stewart, M M Roberts, R J Steele
PMCID: PMC1352620  PMID: 7051998

Abstract

Axillary node sampling was introduced as a means of defining those patients whose primary breast cancer was treated by simple mastectomy in whom postoperative radiotherapy could be avoided safely. The authors have initiated controlled randomized trials in Cardiff and Edinburgh which have indicated that, provided that nodes are identified for histologic examination, simple mastectomy, node sampling, and selective radiotherapy give equal survival rates to routine radical treatment, whether this is by surgery or radiotherapy. Provided sampling of nodes is adequate and histologically proven, locoregional control also is satisfactory. A current randomized trial comparing this policy with Patey mastectomy has allowed comparative studies of axillary node status. These and follow-up data indicate that for a valid assessment, three to four nodes should be identified by the surgeon for histologic examination, the false negative rate being less than 10%.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cant E. L., Shivas A. A., Forrest A. P. Lymph-node biopsy during simple mastectomy. Lancet. 1975 May 3;1(7914):995–997. doi: 10.1016/s0140-6736(75)91944-3. [DOI] [PubMed] [Google Scholar]
  2. Fisher B., Wolmark N., Redmond C., Deutsch M., Fisher E. R. Findings from NSABP Protocol No. B-04: comparison of radical mastectomy with alternative treatments. II. The clinical and biologic significance of medial-central breast cancers. Cancer. 1981 Oct 15;48(8):1863–1872. doi: 10.1002/1097-0142(19811015)48:8<1863::aid-cncr2820480825>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]
  3. Forrest A. P. Advances in the management of breast cancer: physician and surgeon. Scott Med J. 1981 Jul;26(3):199–212. doi: 10.1177/003693308102600304. [DOI] [PubMed] [Google Scholar]
  4. Forrest A. P. Evaluation of treatment of primary cancer of the breast. Proc R Soc Med. 1967 Oct;60(10):938–942. [PMC free article] [PubMed] [Google Scholar]
  5. Forrest A. P., Gleave E. N., Roberts M. M., Henk J. M., Gravelle I. H. A controlled trial of conservative treatment for early breast cancer. Proc R Soc Med. 1970 Feb;63(2):107–110. [PMC free article] [PubMed] [Google Scholar]
  6. Forrest A. P., Roberts M. M., Cant E., Shivas A. Simple mastectomy and pectoral node biopsy. Br J Surg. 1976 Aug;63(8):569–575. doi: 10.1002/bjs.1800630802. [DOI] [PubMed] [Google Scholar]
  7. Langlands A. O., Prescott R. J., Hamilton T. A clinical trial in the management of operable cancer of the breast. Br J Surg. 1980 Mar;67(3):170–174. doi: 10.1002/bjs.1800670304. [DOI] [PubMed] [Google Scholar]
  8. Lythgoe J. P. Manchester regional breast study. Preliminary results. Lancet. 1978 Apr 8;1(8067):744–747. doi: 10.1016/s0140-6736(78)90859-0. [DOI] [PubMed] [Google Scholar]
  9. New Edinburgh primary breast cancer trials. Br J Cancer. 1975 Nov;32(5):628–630. doi: 10.1038/bjc.1975.270. [DOI] [PMC free article] [PubMed] [Google Scholar]

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