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. 1983 Aug;198(2):130–133. doi: 10.1097/00000658-198308000-00002

Hemodynamic consequences of severe pancreatitis.

E L Bradley 3rd, J R Hall, J Lutz, L Hamner, O Lattouf
PMCID: PMC1353067  PMID: 6870367

Abstract

Fifteen patients with severe pancreatitis underwent cardiovascular monitoring in an intensive care unit. The principal findings were a high cardiac index and a decrease in systemic vascular resistance. A significant negative correlation was found to exist between these two parameters (p less than 0.001). Severe pancreatitis apparently results in hemodynamic changes similar to those observed in sepsis. The mechanisms responsible for these observations are not known, although circulating vasoactive compounds resulting from pancreatic necrosis remain a strong possibility. Despite demonstrating a significant decrease in left ventricular stroke work index and an abnormal elevation in pulmonary capillary wedge pressure, the existence of a myocardial depressant factor could not be conclusively proved from these data.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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