Abstract
In a 2-year period (1981-1983), 87 abdominal re-explorations (1.6% of total laparotomies) were performed on 77 patients for sepsis in five Downstate hospitals. Fifty-one patients were re-explored solely on clinical grounds, 21 on clinical plus radiographic criteria, four solely on radiographic grounds, and 11 for multiple organ failure. The overall mortality rate was 43%. As expected, the most common laparotomy finding was intra-abdominal abscess (47); other findings included anastomotic leak (14), necrotic bowel (10), evidence of technical error (five), and acalculous cholecystitis (two). The most common clinical findings were localized tenderness, fever, and absent bowel sounds (85%). Fifty-four special studies were performed with an overall accuracy rate of 76%. CAT scans and contrast radiographs were most accurate (92% and 81%) while sonography and gallium scans were less useful (59% and 60%). Seven patients had negative laparotomies. While all were distended and six were febrile, only one patient had focal tenderness. In the 11 patients explored solely for multiple organ failure, six patients had drainable pus despite negative radiographic studies, and two survived. The other five patients had negative laparotomies, and all died. Factors correlated with mortality were age over 50, peritonitis at the primary operation, and multiple organ failure. The approach to these seriously ill patients should be governed by a high index of suspicion. Clinical findings are at least as reliable as sophisticated radiographic modalities of which CAT scan appears to be the most accurate. Re-exploration for multiple organ failure alone will yield a significant group of patients with drainable septic foci and some survivors; thus, exploration for this indication appears to be defensible.
Full text
PDF





Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Altemeier W. A., Culbertson W. R., Fullen W. D., Shook C. D. Intra-abdominal abscesses. Am J Surg. 1973 Jan;125(1):70–79. doi: 10.1016/0002-9610(73)90010-x. [DOI] [PubMed] [Google Scholar]
- Bartlett R. H., Dechert R. E., Mault J. R., Ferguson S. K., Kaiser A. M., Erlandson E. E. Measurement of metabolism in multiple organ failure. Surgery. 1982 Oct;92(4):771–779. [PubMed] [Google Scholar]
- Baue A. E. Multiple, progressive, or sequential systems failure. A syndrome of the 1970s. Arch Surg. 1975 Jul;110(7):779–781. doi: 10.1001/archsurg.1975.01360130011001. [DOI] [PubMed] [Google Scholar]
- Caffee H. H., Watts G., Mena I. Gallium 67 citrate scanning in the diagnosis of intraabdominal abscess. Am J Surg. 1977 Jun;133(6):665–669. doi: 10.1016/0002-9610(77)90149-0. [DOI] [PubMed] [Google Scholar]
- Damron J. R., Beihn R. M., DeLand F. H. Detection of upper abdominal abscesses by radionuclide imaging. Radiology. 1976 Jul;120(1):131–134. doi: 10.1148/120.1.131. [DOI] [PubMed] [Google Scholar]
- Doust B. D., Doust V. L. Ultrasonic diagnosis of abdominal abscess. Am J Dig Dis. 1976 Jul;21(7):569–576. doi: 10.1007/BF01464765. [DOI] [PubMed] [Google Scholar]
- Driver T., Kelly G. L., Eiseman B. Reoperation after abdominal trauma. Am J Surg. 1978 Jun;135(6):747–750. doi: 10.1016/0002-9610(78)90156-3. [DOI] [PubMed] [Google Scholar]
- Eiseman B., Beart R., Norton L. Multiple organ failure. Surg Gynecol Obstet. 1977 Mar;144(3):323–326. [PubMed] [Google Scholar]
- Fry D. E., Garrison R. N., Heitsch R. C., Calhoun K., Polk H. C., Jr Determinants of death in patients with intraabdominal abscess. Surgery. 1980 Oct;88(4):517–523. [PubMed] [Google Scholar]
- Fry D. E., Pearlstein L., Fulton R. L., Polk H. C., Jr Multiple system organ failure. The role of uncontrolled infection. Arch Surg. 1980 Feb;115(2):136–140. doi: 10.1001/archsurg.1980.01380020006003. [DOI] [PubMed] [Google Scholar]
- Garrison R. N., Ratcliffe D. J., Fry D. E. Hepatocellular function and nutrient blood flow in experimental peritonitis. Surgery. 1982 Oct;92(4):713–719. [PubMed] [Google Scholar]
- Haaga J. R., Alfidi R. J., Havrilla T. R., Cooperman A. M., Seidelmann F. E., Reich N. E., Weinstein A. J., Meaney T. F. CT detection and aspiration of abdominal abscesses. AJR Am J Roentgenol. 1977 Mar;128(3):465–474. doi: 10.2214/ajr.128.3.465. [DOI] [PubMed] [Google Scholar]
- Hill B. A., Yamaguchi K., Flynn J. J., Miller D. R. Diagnostic sonography in general surgery. Arch Surg. 1975 Sep;110(9):1089–1094. doi: 10.1001/archsurg.1975.01360150033006. [DOI] [PubMed] [Google Scholar]
- Hopkins G. B., Kan M., Mende C. W. Gallium-67 scintigraphy and intraabdominal sepsis. Clinical experience in 140 patients with suspected intraabdominal abscess. West J Med. 1976 Dec;125(6):425–430. [PMC free article] [PubMed] [Google Scholar]
- Koehler P. R., Knochel J. Q. Computed tomography in the evaluation of abdominal abscesses. Am J Surg. 1980 Nov;140(5):675–678. doi: 10.1016/0002-9610(80)90056-2. [DOI] [PubMed] [Google Scholar]
- Korobkin M., Callen P. W., Filly R. A., Hoffer P. B., Shimshak R. R., Kressel H. Y. Comparison of computed tomography, ultrasonography, and gallium-67 scanning in the evaluation of suspected abdominal abscess. Radiology. 1978 Oct;129(1):89–93. doi: 10.1148/129.1.89. [DOI] [PubMed] [Google Scholar]
- Kumar B., Alderson P. O., Geisse G. The role of Ga-67 citrate imaging and diagnostic ultrasound in patients with suspected abdominal abscesses. J Nucl Med. 1977 Jun;18(6):534–537. [PubMed] [Google Scholar]
- LOWDON A. G. Emergency re-operation in abdominal surgery. J R Coll Surg Edinb. 1959 Jul;4:291–304. [PubMed] [Google Scholar]
- Lorenc J. Early urgent relaparotomy in abdominal surgery. Int Surg. 1969 May;51(5):433–437. [PubMed] [Google Scholar]
- Norton L., Eule J., Burdick D. Accuracy of techniques to detect intraperitoneal abscess. Surgery. 1978 Sep;84(3):370–378. [PubMed] [Google Scholar]
- Polk H. C., Jr, Shields C. L. Remote organ failure: a valid sign of occult intra-abdominal infection. Surgery. 1977 Mar;81(3):310–313. [PubMed] [Google Scholar]
- Richardson J. D., Fry D. E., Van Arsdall L., Flint L. M., Jr Delayed pulmonary clearance of gram-negative bacteria: the role of intraperitoneal sepsis. J Surg Res. 1979 May;26(5):499–503. doi: 10.1016/0022-4804(79)90040-4. [DOI] [PubMed] [Google Scholar]
- Richardson R., Norton L. W., Eule J., Eiseman B. Accuracy of ultrasound in diagnosing abdominal masses. Arch Surg. 1975 Aug;110(8):933–939. doi: 10.1001/archsurg.1975.01360140077016. [DOI] [PubMed] [Google Scholar]
- Robison J. G., Pollock T. W. Computed tomography in the diagnosis and localization of intraabdominal abscesses. Am J Surg. 1980 Dec;140(6):783–786. doi: 10.1016/0002-9610(80)90117-8. [DOI] [PubMed] [Google Scholar]
- Roche J. Effectiveness of computed tomography in the diagnosis of intra-abdominal abscess: A review of 111 patients. Med J Aust. 1981 Jul 25;2(2):85-6, 87-8. [PubMed] [Google Scholar]
- Saini S., Kellum J. M., O'Leary M. P., O'Donnell T. F., Tally F. P., Carter B., Deterling R. A., Curtis L. E. Improved localization and survival in patients with intraabdominal abscesses. Am J Surg. 1983 Jan;145(1):136–142. doi: 10.1016/0002-9610(83)90180-0. [DOI] [PubMed] [Google Scholar]
- Shimshak R. R., Korobkin M., Hoffer P. B., Schor R., Hill T. C., Kressel H. Y. The complementary role of gallium citrate imaging and computed tomography in the evaluation of suspected abdominal infection. J Nucl Med. 1978 Mar;19(3):262–269. [PubMed] [Google Scholar]
- Wolverson M. K., Jagannadharao B., Sundaram M., Joyce P. F., Riaz M. A., Shields J. B. CT as a primary diagnostic method in evaluating intraabdominal abscess. AJR Am J Roentgenol. 1979 Dec;133(6):1089–1095. doi: 10.2214/ajr.133.6.1089. [DOI] [PubMed] [Google Scholar]
