Skip to main content
PMC home page
The Journal of Physiology logoLink to The Journal of Physiology
. 1977 Dec;273(1):263–275. doi: 10.1113/jphysiol.1977.sp012093

Neuromuscular transmission in arterioles of guinea-pig submucosa.

G D Hirst
PMCID: PMC1353738  PMID: 202698

Abstract

1. Intracellular recordings were made from arterioles lying in the submucosa of guinea-pig small intestine. 2. Low frequency perivascular nerve stimulation evoked subthreshold excitatory junction potentials which facilitated. 3. Higher frequency stimulation caused summation of excitatory junction potentials and the initiation of muscle action potentials. 4. Arteriolar constriction was only observed following the initiation of a muscle action potential.

Full text

PDF
263

Images in this article

274-2Plate 1
on p.274-2

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BURNSTOCK G., HOLMAN M. E., KURIYAMA H. FACILITATION OF TRANSMISSION FROM AUTONOMIC NERVE TO SMOOTH MUSCLE OF GUINEA-PIG VAS DEFERENS. J Physiol. 1964 Jul;172:31–49. doi: 10.1113/jphysiol.1964.sp007401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BURNSTOCK G., HOLMAN M. E. The transmission of excitation from autonomic nerve to smooth muscle. J Physiol. 1961 Jan;155:115–133. doi: 10.1113/jphysiol.1961.sp006617. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bell C. Transmission from vasoconstrictor and vasodilator nerves to single smooth muscle cells of the guinea-pig uterine artery. J Physiol. 1969 Dec;205(3):695–708. doi: 10.1113/jphysiol.1969.sp008991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bennett M. R. An electrophysiological analysis of the uptake of noradrenaline at sympathetic nerve terminals. J Physiol. 1973 Mar;229(2):533–546. doi: 10.1113/jphysiol.1973.sp010152. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Biber B., Fara J., Lundgren O. Intestinal vasodilatation in response to transmural electrical field stimulation. Acta Physiol Scand. 1973 Feb;87(2):277–282. doi: 10.1111/j.1748-1716.1973.tb05391.x. [DOI] [PubMed] [Google Scholar]
  6. Casteels R., Droogmans G. Membrane potential and excitation-contraction coupling in the smooth muscle cells of the rabbit ear artery [proceedings]. J Physiol. 1976 Dec;263(1):163P–164P. [PubMed] [Google Scholar]
  7. Furness J. B. Arrangement of blood vessels and their relation with adrenergic nerves in the rat mesentery. J Anat. 1973 Sep;115(Pt 3):347–364. [PMC free article] [PubMed] [Google Scholar]
  8. Gabella G., Juorio A. V. Effect of extrinsic denervation on endogenous noradrenaline and (3H)noradrenaline uptake in the guinea-pig colon. J Neurochem. 1975 Nov;25(5):631–634. doi: 10.1111/j.1471-4159.1975.tb04379.x. [DOI] [PubMed] [Google Scholar]
  9. Hirst G. D., Holman M. E., Spence I. Two types of neurones in the myenteric plexus of duodenum in the guinea-pig. J Physiol. 1974 Jan;236(2):303–326. doi: 10.1113/jphysiol.1974.sp010436. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hirst G. D., McKirdy H. C. Synaptic potentials recorded from neurones of the submucous plexus of guinea-pig small intestine. J Physiol. 1975 Jul;249(2):369–385. doi: 10.1113/jphysiol.1975.sp011020. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Holman M. E., Taylor G. S., Tomita T. Some properties of the smooth muscle of mouse vas deferens. J Physiol. 1977 Apr;266(3):751–764. doi: 10.1113/jphysiol.1977.sp011791. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Hubbard J. I. Microphysiology of vertebrate neuromuscular transmission. Physiol Rev. 1973 Jul;53(3):674–723. doi: 10.1152/physrev.1973.53.3.674. [DOI] [PubMed] [Google Scholar]
  13. Kitamura K., Kuriyama H., Suzuki H. Effect of noradrenaline on the membrane properties and on the contraction of the rabbit main pulmonary artery [proceedings]. J Physiol. 1976 Dec;263(1):164P–165P. [PubMed] [Google Scholar]
  14. Mekata F. Current spread in the smooth muscle of the rabbit aorta. J Physiol. 1974 Oct;242(1):143–155. doi: 10.1113/jphysiol.1974.sp010698. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Mekata F. Rectification in the smooth muscle cell membrane of rabbit aorta. J Physiol. 1976 Jun;258(2):269–278. doi: 10.1113/jphysiol.1976.sp011419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Reuter H. Divalent cations as charge carriers in excitable membranes. Prog Biophys Mol Biol. 1973;26:1–43. doi: 10.1016/0079-6107(73)90016-3. [DOI] [PubMed] [Google Scholar]
  17. Somlyo A. P., Somlyo A. V. Vascular smooth muscle. I. Normal structure, pathology, biochemistry, and biophysics. Pharmacol Rev. 1968 Dec;20(4):197–272. [PubMed] [Google Scholar]
  18. Tomita T. Current spread in the smooth muscle of the guinea-pig vas deferens. J Physiol. 1967 Mar;189(1):163–176. doi: 10.1113/jphysiol.1967.sp008161. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES