Fig. 3.

Changes of the mRNA expression of the pro-inflammatory cytokines TNF-α (A), IL-1β (B), and IL-6 (C) and the anti-inflammatory cytokine IL-10 (D) following QA and GA icv injections in the cerebral cortex of WT and Gcdh^−/− mice on PND 8. Data are presented as mean ± standard deviation (SD), with n = 3–5 animals per group. Statistical analysis was performed using two-way ANOVA followed by the Tukey’s post hoc test (**P < 0.01, ***P < 0.001, differences from PBS + PBS + PBS; ^##P < 0.01, ^###P < 0.001, differences from PBS + PBS + GA; ^$$P < 0.01, ^$$$P < 0.001 differences from PBS + QA + GA; ^@@P < 0.01, differences from genotype)