Skip to main content
The Journal of Physiology logoLink to The Journal of Physiology
. 1965 Oct;180(4):741–753. doi: 10.1113/jphysiol.1965.sp007728

An autoradiographic study of the incorporation of nucleic-acid precursors by neurones and glia during nerve regeneration.

W E Watson
PMCID: PMC1357419  PMID: 5880359

Full text

PDF
741

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALTMAN J. DIFFERENCES IN THE UTILIZATION OF TRITIATED LEUCINE BY SINGLE NEURONES IN NORMAL AND EXERCISED RATS: AN AUTORADIOGRAPHIC INVESTIGATION WITH MICRODENSITOMETRY. Nature. 1963 Aug 24;199:777–780. doi: 10.1038/199777a0. [DOI] [PubMed] [Google Scholar]
  2. Aitken J. T., Sharman M., Young J. Z. Maturation of regenerating nerve fibres with various peripheral connexions. J Anat. 1947 Jan;81(Pt 1):1–22.2. [PMC free article] [PubMed] [Google Scholar]
  3. BRATTGARD S. O., EDSTROM J. E., HYDEN H. The chemical changes in regenerating neurons. J Neurochem. 1957;1(4):316–325. doi: 10.1111/j.1471-4159.1957.tb12088.x. [DOI] [PubMed] [Google Scholar]
  4. BRATTGARD S. O., HYDEN H., SJOSTRAND J. Incorporation of orotic acid-14c and lysine-14c in regenerating single nerve cells. Nature. 1958 Sep 20;182(4638):801–802. doi: 10.1038/182801b0. [DOI] [PubMed] [Google Scholar]
  5. EDSTROM J. E. Ribonucleic acid mass and concentration in individual nerve cells; a new method for quantitative determinations. Biochim Biophys Acta. 1953 Nov;12(3):361–386. doi: 10.1016/0006-3002(53)90155-3. [DOI] [PubMed] [Google Scholar]
  6. FEINENDEGEN L. E., BOND V. P. Observations on nuclear RNA during mitosis in human cancer cells in culture (HeLa-S3), studied with tritiated cytidine. Exp Cell Res. 1963 Apr;30:393–404. doi: 10.1016/0014-4827(63)90311-2. [DOI] [PubMed] [Google Scholar]
  7. FISCHER J., LODIN Z., KOLOUSEK J. A histoautoradiographic study of the effect of section of the facial nerve on the uptake of methionine-35S by the cells of the facial nerve nucleus. Nature. 1958 Feb 1;181(4605):341–342. doi: 10.1038/181341a0. [DOI] [PubMed] [Google Scholar]
  8. FITZGERALD P. J., VINIJCHAIKUL K. Nucleic acid metabolism of pancreatic cells as revealed by cytidine-H3 and thymidine-H3. Lab Invest. 1959 Jan-Feb;8(1):319–329. [PubMed] [Google Scholar]
  9. FRIEDE R. L. INTERPRETATION OF HYPERCHROMIC NERVE CELLS: RELATIVE SIGNIFICANCE OF THE TYPE OF FIXATIVE USED, OF THE OSMOLARITY OF THE CYTOPLASM AND THE SURROUNDING FLUID IN THE PRODUCTION OF CELL SHRINKAGE. J Comp Neurol. 1963 Aug;121:137–149. doi: 10.1002/cne.901210110. [DOI] [PubMed] [Google Scholar]
  10. FRIEDE R. L. The cytochemistry of normal and reactive astrocytes. J Neuropathol Exp Neurol. 1962 Jul;21:471–478. doi: 10.1097/00005072-196207000-00015. [DOI] [PubMed] [Google Scholar]
  11. FRIEDE R. L. Transport of oxidative enzymes in nerve fibers: a histochemical investigation of the regenerative cycle in neurons. Exp Neurol. 1959 Nov;1:441–466. doi: 10.1016/0014-4886(59)90043-3. [DOI] [PubMed] [Google Scholar]
  12. GEIGER A., YAMASAKI S. Cytidine and uridine requirement of the brain. J Neurochem. 1956 Dec;1(2):93–100. doi: 10.1111/j.1471-4159.1956.tb12059.x. [DOI] [PubMed] [Google Scholar]
  13. GOLDSTEIN L., MICO U. J., CROCKER T. T. Nuclear-cytoplasmic relationships in human cells in tissue culture. IV. A study of some aspects of nucleic acid and protein metabolism in enucleate cells. Biochim Biophys Acta. 1960 Dec 4;45:82–86. doi: 10.1016/0006-3002(60)91428-1. [DOI] [PubMed] [Google Scholar]
  14. GROS F., HIATT H., GILBERT W., KURLAND C. G., RISEBROUGH R. W., WATSON J. D. Unstable ribonucleic acid revealed by pulse labelling of Escherichia coli. Nature. 1961 May 13;190:581–585. doi: 10.1038/190581a0. [DOI] [PubMed] [Google Scholar]
  15. Goldstein L., Plaut W. DIRECT EVIDENCE FOR NUCLEAR SYNTHESIS OF CYTOPLASMIC RIBOSE NUCLEIC ACID. Proc Natl Acad Sci U S A. 1955 Nov 15;41(11):874–880. doi: 10.1073/pnas.41.11.874. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. HALEY T. J., MCCORMICK W. G. Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse. Br J Pharmacol Chemother. 1957 Mar;12(1):12–15. doi: 10.1111/j.1476-5381.1957.tb01354.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. JACOB F., MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318–356. doi: 10.1016/s0022-2836(61)80072-7. [DOI] [PubMed] [Google Scholar]
  18. KIMBALL R. F., PERDUE S. W. Quantitative cytochemical studies on Paramecium. V. Autoradiographic studies of nucleic acid syntheses. Exp Cell Res. 1962 Sep;27:405–415. doi: 10.1016/0014-4827(62)90005-8. [DOI] [PubMed] [Google Scholar]
  19. LASANSKY A. Morphological bases for a nursing role of glia in the toad retina. Electron microscope observations. J Biophys Biochem Cytol. 1961 Oct;11:237–243. doi: 10.1083/jcb.11.1.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. PERRY R. P., ERRERA M. The role of the nucleolus in ribonucleic acid-and protein synthesis. I. Incorporation of cytidine into normal and nucleolar inactivated HeLa cells. Biochim Biophys Acta. 1961 Apr 29;49:47–57. doi: 10.1016/0006-3002(61)90868-x. [DOI] [PubMed] [Google Scholar]
  21. ROBERTSON J. S. Theory and use of tracers in determining transfer rates in biological systems. Physiol Rev. 1957 Apr;37(2):133–154. doi: 10.1152/physrev.1957.37.2.133. [DOI] [PubMed] [Google Scholar]
  22. STENRAM U. Interferometric determinations of the ribose nucleic acid concentration in liver nucleoli of protein-fed and protein-deprived rats. Exp Cell Res. 1958 Aug;15(1):174–183. doi: 10.1016/0014-4827(58)90073-9. [DOI] [PubMed] [Google Scholar]
  23. WOODS P. S., TAYLOR J. H. Studies of ribonucleic acid metabolism with tritium-labeled cytidine. Lab Invest. 1959 Jan-Feb;8(1):309–318. [PubMed] [Google Scholar]
  24. ZALOKAR M. Nuclear origin of ribonucleic acid. Nature. 1959 May 9;183(4671):1330–1330. doi: 10.1038/1831330a0. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES