Abstract
1. The net movements of Na and K into resting squid giant axons perfused with a K2SO4 artificial axoplasm have been determined. Na enters at a rate of 131 ± 25 p-mole/cm2.sec. The K leakage from the fibre is 942 ± 566 p-mole/cm2.sec; clearly this latter figure shows how large is the uncertainty in the exact value for the potassium leakage.
2. The net entry of sodium associated with activity in such fibres has been measured and is 5·7 ± 0·7 p-mole/cm2.impulse.
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