Abstract
1. The subcellular distribution pattern of kallikrein was compared with that of amylase and acetylcholine in submaxillary gland homogenates of the guinea-pig.
2. Kallikrein was located in particles which sedimented in the nuclear (46%) and mitochondrial (17%) fractions. These particles were probably similar if not identical to zymogen granules.
3. The above observations would support a digestive role for salivary kallikrein.
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Selected References
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