Skip to main content
Annals of Surgery logoLink to Annals of Surgery
. 1990 May;211(5):600–604.

Operative risks of the implantable defibrillator versus endocardial resection.

I L Kron 1, D E Haines 1, C G Tribble 1, L H Blackbourne 1, T L Flanagan 1, C E Hobson 1, J P DiMarco 1
PMCID: PMC1358232  PMID: 2339921

Abstract

Both map-guided endocardial resection (ER) and the automatic implantable cardioverter defibrillator (AICD) are currently used for surgical treatment of patients who have sustained ventricular tachyarrhythmias. Some authors have preferred AICD implant due to a lower published operative mortality rate. To determine if there is a discrepancy in mortality rates between the two techniques, we analyzed hospital survival in 46 patients undergoing ER and in 44 patients undergoing AICD implantation during the same 3-year period. Two ER patients (4%) died before hospital discharge. Two patients (4%) died after AICD implantation. At predischarge electrophysiologic study five patients (11%) had inducible ventricular tachycardia and received antiarrhythmic drug therapy after ER. In contrast 35 of 42 patients surviving AICD placement received chronic long-term antiarrhythmic therapy (p less than 0.05 compared to ER). Our experience shows that ER and AICD placement may be carried out with similar procedure-related mortality and morbidity rates. Lower operative risks should not be a reason for choosing the AICD over ER for surgical treatment of ventricular tachyarrhythmias. The AICD may actually improve the results of ER by offering an alternative to ventriculotomy in poor-risk surgical candidates.

Full text

PDF
600

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Elefteriades J. A., Biblo L. A., Batsford W. P., Rosenfeld L. E., Henthorn R. W., Carlson M. D., Waldo A. L., Hsu J., Geha A. S. Evolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias. Ann Thorac Surg. 1990 Jan;49(1):94–100. doi: 10.1016/0003-4975(90)90362-a. [DOI] [PubMed] [Google Scholar]
  2. Fonger J. D., Guarnieri T., Griffith L. S., Veltri E., Levine J., Mower M., Mirowski M., Grunwald L., Watkins L., Jr Impending sudden cardiac death: treatment with myocardial revascularization and the automatic implantable cardioverter defibrillator. Ann Thorac Surg. 1988 Jul;46(1):13–19. doi: 10.1016/s0003-4975(10)65843-2. [DOI] [PubMed] [Google Scholar]
  3. Greenberg M. L., Lerman B. B., Shipe J. R., Kaiser D. L., DiMarco J. P. Relation between amiodarone and desethylamiodarone plasma concentrations and electrophysiologic effects, efficacy and toxicity. J Am Coll Cardiol. 1987 May;9(5):1148–1155. doi: 10.1016/s0735-1097(87)80320-0. [DOI] [PubMed] [Google Scholar]
  4. Haines D. E., Lerman B. B., Kron I. L., DiMarco J. P. Surgical ablation of ventricular tachycardia with sequential map-guided subendocardial resection: electrophysiologic assessment and long-term follow-up. Circulation. 1988 Jan;77(1):131–141. doi: 10.1161/01.cir.77.1.131. [DOI] [PubMed] [Google Scholar]
  5. Hammon J. W., Jr, Echt D. S., Merrill W. H., Primm K. R., Woosley R. L., Smith R. F., Roden D. M., Bender H. W., Jr Indications for different modes of surgical therapy in medically refractory ventricular arrhythmias. Ann Surg. 1986 Jun;203(6):679–684. doi: 10.1097/00000658-198606000-00013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hargrove W. C., 3rd, Josephson M. E., Marchlinski F. E., Miller J. M. Surgical decisions in the management of sudden cardiac death and malignant ventricular arrhythmias. Subendocardial resection, the automatic internal defibrillator, or both. J Thorac Cardiovasc Surg. 1989 Jun;97(6):923–928. [PubMed] [Google Scholar]
  7. Kelly P. A., Wallace S., Tucker B., Hurvitz R. J., Ilvento J., Mirabel G. S., Cannom D. S. Postoperative infection with the automatic implantable cardioverter defibrillator: clinical presentation and use of the gallium scan in diagnosis. Pacing Clin Electrophysiol. 1988 Aug;11(8):1220–1225. doi: 10.1111/j.1540-8159.1988.tb03975.x. [DOI] [PubMed] [Google Scholar]
  8. Kron I. L., Flanagan T. L., Blackbourne L. H., Schroeder R. A., Nolan S. P. Coronary revascularization rather than cardiac transplantation for chronic ischemic cardiomyopathy. Ann Surg. 1989 Sep;210(3):348–354. doi: 10.1097/00000658-198909000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kron I. L., Lerman B. B., DiMarco J. P. Extended subendocardial resection. A surgical approach to ventricular tachyarrhythmias that cannot be mapped intraoperatively. J Thorac Cardiovasc Surg. 1985 Oct;90(4):586–591. [PubMed] [Google Scholar]
  10. Kron I. L., Lerman B. B., Haines D. E., Flanagan T. L., DiMarco J. P. Coronary artery bypass grafting in patients with ventricular fibrillation. Ann Thorac Surg. 1989 Jul;48(1):85–89. doi: 10.1016/0003-4975(89)90185-9. [DOI] [PubMed] [Google Scholar]
  11. Kron I. L., Lerman B. B., Nolan S. P., Flanagan T. L., Haines D. E., DiMarco J. P. Sequential endocardial resection for the surgical treatment of refractory ventricular tachycardia. J Thorac Cardiovasc Surg. 1987 Dec;94(6):843–847. [PubMed] [Google Scholar]
  12. Luceri R. M., Habal S. M., Castellanos A., Thurer R. J., Waters R. S., Brownstein S. L. Mechanism of death in patients with the automatic implantable cardioverter defibrillator. Pacing Clin Electrophysiol. 1988 Nov;11(11 Pt 2):2015–2022. doi: 10.1111/j.1540-8159.1988.tb06343.x. [DOI] [PubMed] [Google Scholar]
  13. Manolis A. S., Rastegar H., Estes N. A., 3rd Automatic implantable cardioverter defibrillator. Current status. JAMA. 1989 Sep 8;262(10):1362–1368. [PubMed] [Google Scholar]
  14. Mercando A. D., Furman S., Johnston D., Frame R., Brodman R., Kim S. G., Fisher J. D. Survival of patients with the automatic implantable cardioverter defibrillator. Pacing Clin Electrophysiol. 1988 Nov;11(11 Pt 2):2059–2063. doi: 10.1111/j.1540-8159.1988.tb06350.x. [DOI] [PubMed] [Google Scholar]
  15. Nygaard T. W., Sellers T. D., Cook T. S., DiMarco J. P. Adverse reactions to antiarrhythmic drugs during therapy for ventricular arrhythmias. JAMA. 1986 Jul 4;256(1):55–57. [PubMed] [Google Scholar]
  16. Olinger G. N., Chapman P. D., Troup P. J., Almassi G. H. Stratified application of the automatic implantable cardioverter defibrillator. J Thorac Cardiovasc Surg. 1988 Jul;96(1):141–149. [PubMed] [Google Scholar]
  17. Slater A. D., Singer I., Stavens C. S., Zee-Cheng C., Ganzel B. L., Kupersmith J., Mavroudis C., Gray L. A., Jr Treatment of malignant ventricular arrhythmias with the automatic implantable cardioverter defibrillator. Ann Surg. 1989 May;209(5):635–641. doi: 10.1097/00000658-198905000-00017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Thurer R. J., Luceri R. M., Bolooki H. Automatic implantable cardioverter-defibrillator: techniques of implantation and results. Ann Thorac Surg. 1986 Aug;42(2):143–147. doi: 10.1016/s0003-4975(10)60507-3. [DOI] [PubMed] [Google Scholar]
  19. Tyers G. F. Impending sudden cardiac death: treatment with myocardial revascularization and the automatic implantable cardioverter defibrillator. Ann Thorac Surg. 1988 Jul;46(1):1–2. doi: 10.1016/s0003-4975(10)65840-7. [DOI] [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES