Skip to main content
Frontiers in Psychiatry logoLink to Frontiers in Psychiatry
. 2026 Sep 4;17:1927279. doi: 10.3389/fpsyt.2026.1927279

Follow-up attendance and documented reasons for non-attendance in child and adolescent mental health care: a retrospective analysis

Serkan Suren 1,†, Deniz Yavuz Baskiran 2,*,†
PMCID: PMC13587137  PMID: 42761443

Abstract

Background

Failure to continue scheduled follow-up is a common challenge in child and adolescent mental health services and may reduce treatment effectiveness.

Objective

The present retrospective study aimed to examine demographic, clinical, and treatment-related characteristics associated with attendance at the last scheduled follow-up appointment among children and adolescents receiving outpatient psychiatric care and to identify characteristics associated with the documented reasons for non-attendance among patients who missed their last scheduled follow-up appointment.

Methods

A retrospective study was conducted using medical records of 841 patients aged 1–18 years who attended a tertiary child and adolescent psychiatry outpatient clinic between 2015 and 2026. Demographic, clinical, and treatment-related characteristics were summarized descriptively. Associations between categorical variables were examined using Pearson’s chi-square test, and effect sizes were reported using Cramér’s V.

Results

Of the 841 patients, 142 had no scheduled follow-up appointment and were excluded from the attendance analysis. Among the remaining 699 patients, 56.8% attended their last scheduled follow-up appointment. No significant associations were observed between attendance and the demographic, clinical, or treatment-related characteristics examined. Among the 302 non-attendees, unspecified reasons (36.8%) and scheduling conflicts (17.5%) were most frequent. Documented reasons for non-attendance were significantly associated with medication prescription status (χ² = 9.749, p = 0.008, Cramér’s V = 0.181) and drug class (χ² = 10.202, p = 0.037, Cramér’s V = 0.130).

Conclusions

Last scheduled follow-up attendance was not significantly associated with the demographic, clinical, or treatment-related characteristics examined. Among non-attendees, documented reasons for non-attendance were associated with medication prescription status and drug class. Systematic documentation of non-attendance reasons may help identify barriers to continuity of care and inform targeted follow-up strategies.

Keywords: adverse drug reactions, child and adolescent psychiatry, polypharmacy, retrospective study, treatment adherence

1. Introduction

Treatment adherence is a fundamental component of child and adolescent mental health services because the long-term course of psychiatric disorders such as attention-deficit/hyperactivity disorder (ADHD), anxiety disorders, obsessive-compulsive disorder (OCD), and autism spectrum disorder (ASD) largely depends on regular follow-up and continuity of care (1–3). Early discontinuation of follow-up has been associated with symptom recurrence, functional deterioration, increased healthcare utilization, and greater family burden (4, 5). Nevertheless, non-attendance rates for follow-up appointments in child and adolescent mental health services frequently exceed 50%, making the identification of factors contributing to treatment discontinuation a major priority for both clinical practice and research (6, 7). Numerous factors influencing continuity of follow-up have been investigated in the literature and can generally be classified into three categories: (i) patient- and family-related characteristics (e.g., age, sex, socioeconomic status, and previous psychiatric treatment history), (ii) clinical characteristics (e.g., diagnosis, illness severity, psychiatric comorbidity, and treatment complexity), and (iii) treatment-related factors (e.g., pharmacological treatment, adverse drug reactions, perceived treatment benefit, and the therapeutic alliance) (6–8). Existing reviews indicate that treatment discontinuation in child and adolescent mental health care is influenced by multiple interacting factors and that findings vary according to study design and the operational definition of dropout. A meta-analytic review of child and adolescent outpatient mental health care reported that dropout rates differed substantially between efficacy and effectiveness studies and that treatment-, therapist-, and participation-related barriers generally showed stronger associations with dropout than pretreatment child or family characteristics (4). More recently, a systematic review among youth with severe and enduring mental health problems identified treatment type, engagement, transparency and communication, goodness of fit between the young person and treatment, and practitioner-related perspectives as particularly relevant factors associated with treatment failure and dropout (7). Together, these findings suggest that discontinuation cannot be explained solely by demographic or diagnostic characteristics and should also be examined in relation to treatment processes, family engagement, and service-level factors. However, there is no consensus regarding the relative contribution of these factors to follow-up continuity. While some studies have identified demographic and sociocultural characteristics as the primary determinants (9), others have suggested that illness severity, treatment intensity, and adverse drug reactions play a more influential role (7). Adverse drug reactions (ADRs) are of particular interest because they represent potentially modifiable factors. However, evidence regarding the association between ADRs and treatment adherence in children and adolescents remains inconsistent. Some studies have reported that adverse effects such as weight gain or behavioral activation substantially reduce treatment adherence (10, 11), whereas others have found that this association is no longer significant after controlling for the type of medication prescribed (12). The present retrospective study aimed to examine demographic, clinical, and treatment-related characteristics associated with attendance at the last scheduled follow-up appointment among children and adolescents receiving outpatient psychiatric care, to describe the documented reasons for non-attendance, and to identify characteristics associated with these reasons among patients who missed their last scheduled follow-up appointment.

1.1. Research questions

RQ1. Which demographic, clinical, and treatment-related characteristics are associated with attendance at the last scheduled follow-up appointment among children and adolescents receiving outpatient psychiatric care?

RQ2. What are the documented reasons for missing the last scheduled follow-up appointment among patients who did not attend?

RQ3. Among patients who missed their last scheduled follow-up appointment, are the documented reasons for non-attendance associated with sociodemographic and treatment-related characteristics?

2. Methods

2.1. Study design and setting

This retrospective observational study was conducted at the outpatient child and adolescent psychiatry clinic of a tertiary referral center. The clinic provides comprehensive psychiatric assessment, pharmacological treatment, and brief psychotherapeutic interventions for children and adolescents referred by families, schools, and primary healthcare services. A retrospective observational design was considered appropriate because the study aimed to evaluate follow-up attendance and treatment discontinuation using electronic medical records collected during routine clinical practice (13). This study was reported in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement (14).

2.2. Study population

The study included all patients aged 1–18 years who attended at least one psychiatric outpatient evaluation between 2015 and 2026. The study period was defined from 2015 onwards because the electronic medical record system was implemented and maintained consistently from that year, allowing standardized retrieval of clinical information throughout the study period. No exclusion criteria were applied regarding psychiatric diagnosis, comorbidity, or treatment status. Prior to analysis, electronic medical records were reviewed for completeness and consistency. Patients with incomplete medical records that did not contain sufficient information for the variables included in the study were excluded. Consequently, 841 patients met the study eligibility criteria and were included in the final analyses.

2.3. Data collection

Demographic, clinical, and treatment-related information was extracted retrospectively from the electronic medical records using a structured data collection form. Variables included sex, age group, place of residence, presenting complaint, primary psychiatric diagnosis, psychiatric comorbidity, medication prescription, medication group, adverse drug reactions, referral source, administration of standardized psychological tests, number of outpatient visits, first and last visit dates, follow-up duration, attendance at the last scheduled appointment, and the documented reason for missing the last appointment. Psychiatric diagnoses were established according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). For descriptive analyses, medication regimens were classified as stimulant monotherapy, antidepressant monotherapy, antipsychotic monotherapy, polypharmacy (≥2 medication classes), or no pharmacological treatment.

2.4. Outcome variable

The primary outcome was attendance at the last scheduled outpatient follow-up appointment. Attendance was recorded as a binary variable (attended/not attended) according to the medical records. For patients without a scheduled follow-up appointment, attendance at the last scheduled follow-up was considered not applicable, and these patients were excluded from the attendance analysis. Follow-up appointments were scheduled by the treating psychiatrist according to the patient’s clinical condition and routine clinical practice. Therefore, the interval between appointments was not fixed but reflected routine clinical care. For patients who missed their last scheduled appointment, the documented reason for non-attendance was extracted from the medical records. For descriptive analyses, the documented reasons were grouped into three categories: treatment-related reasons, social reasons, and unspecified reasons. Treatment-related reasons included perceived clinical improvement, treatment resistance or inadequate treatment response, refusal of pharmacological treatment, lack of parental motivation, and medication side effects, whereas social reasons included scheduling conflicts, transportation problems, patient or family illness, financial difficulties, and social events (e.g., weddings or funerals). Reasons that were not recorded in the medical records were classified as unspecified.

2.5. Statistical analysis

Continuous variables were summarized as mean ± standard deviation (SD), whereas categorical variables were presented as frequencies and percentages. Associations between categorical variables and last appointment attendance were examined using Pearson’s chi-square test, and effect sizes were reported as Cramér’s V. To further characterize missed follow-up appointments, selected sociodemographic and clinical variables (sex, comorbidity, medication prescription status, adverse effects, and drug class) were compared according to the documented reasons for missing the last scheduled follow-up appointment using Pearson’s chi-square test. Because medication classes included sparse categories, they were collapsed into three clinically meaningful groups (monotherapy, polypharmacy/other, and non-pharmacological treatment) for this analysis. Analyses were conducted using available cases for each variable; therefore, analytic denominators varied slightly because of missing data. Statistical significance was defined as p < 0.05. All statistical analyses were performed using IBM SPSS Statistics version 26.0 (IBM Corp., Armonk, NY, USA).

2.6. Ethical considerations

The study was conducted in accordance with the principles of the Declaration of Helsinki. Ethical approval was obtained from the İnönü University Non-Interventional Clinical Research Ethics Committee (Decision No. 2026/10411, Session Date: 16 June 2026). As this was a retrospective study based on routinely collected clinical records, the requirement for informed consent was waived by the ethics committee.

3. Results

A total of 841 patients were included in the study. The mean follow-up duration was 612 days [median, 312 days; interquartile range (IQR), 52–868 days], and the mean number of outpatient visits was 7.1 (median, 5; IQR, 2–10). Of the 841 patients, 142 had no scheduled follow-up appointment and were therefore excluded from the analysis of last scheduled follow-up attendance. Among the remaining 699 patients, 397 (56.8%) attended their last scheduled follow-up appointment, whereas 302 (43.2%) did not attend.

3.1. Demographic and clinical characteristics

Table 1 summarizes the demographic, clinical, and treatment characteristics of the sample. The study sample was predominantly male (68.0%) and school-aged (72.4% aged 7–18 years). The most common primary diagnosis groups were neurodevelopmental disorders (33.4%), ADHD (30.3%), and anxiety/depression/OCD disorders (29.5%). Comorbidity was present in 62.4% of patients. Regarding treatment, 36.5% received monotherapy, 50.7% received polypharmacy/other treatment, and 12.8% received non-pharmacological treatment.

Table 1.

Demographic, clinical, and treatment characteristics of the study sample (N = 841).

Characteristic n (%) Characteristic n (%)
Sex Drug class (Multiple responses were allowed)
Male 572 (68.0)
Female 269 (32.0) Monotherapy 307 (36.5)
Age group Polypharmacy/other 426 (50.7)
1–3 years 53 (6.3) Non-pharmacological treatment 108 (12.8)
4–6 years 179 (21.3) Follow-up appointment status
7–11 years 314 (37.3) Yes 397 (47.2)
12–18 years 295 (35.1) No 302 (35.9)
Primary diagnosis No scheduled follow-up 142 (16.9)
ADHD 255 (30.3)
Anxiety/Depression/OCD disorders 248 (29.5) Side effect reported
Neurodevelopmental disorders 281 (33.4) Yes 216 (25.7)
Mood and psychotic disorders 7 (0.8) No 500 (59.5)
Other psychiatric disorders 15 (1.8) Not applicable 125 (14.9)
No diagnosis 35 (4.2) Follow-up duration (days)
No follow-up scheduled 142 (16.9)
Comorbidity 2–5 weeks 120 (14.3)
Yes 525 (62.4) 6–8 weeks 99 (11.8)
No 316 (37.6) 3–5 months 92 (10.9)
Psychological testing ≥6 months 388 (46.1)
Yes 381 (45.3) Continuous variables Mean ± SD
No 460 (54.7) Number of visits 7.14 ± 6.89

n, number of patients; %, percentage; SD, standard deviation; OCD, Obsessive-Compulsive Disorder; SLD, Specific Learning Disorder; ASD, Autism Spectrum Disorder. Percentages may not total 100% due to rounding. Bold text is used to distinguish variable/category headings.

3.2. Reasons for missing the last follow-up appointment

Table 2 summarizes the documented reasons for missing the last scheduled follow-up appointment among the 302 patients who did not attend. The reason for non-attendance was not documented in 36.8% of cases. Among cases with a documented reason, scheduling conflicts were the most frequently reported (17.5%), followed by transportation problems and clinical improvement (7.6% each), social reasons (7.0%), and patient or family illness (6.6%). Medication side effects accounted for only 1.3% of missed appointments.

Table 2.

Documented reasons for missing the last scheduled follow-up appointment among patients who missed their last appointment (N = 302).

Characteristic n %
Scheduling conflict 53 17.5
Transportation problems 23 7.6
Clinical improvement 23 7.6
Social reasons (e.g., wedding, funeral) 21 7.0
Patient or family illness 20 6.6
Treatment resistance / inadequate treatment response 12 4.0
Refusal of pharmacological treatment 11 3.6
Lack of parental motivation 12 4.0
Financial reasons 12 4.0
Medication side effects 4 1.3
Not specified 111 36.8

n, number of patients; %, percentage.

3.3. Bivariate analyses

Of the 841 patients included in the study, 142 had no scheduled follow-up appointment and were therefore excluded from the analysis of last scheduled follow-up attendance. Table 3 presents the bivariate associations between study variables and last scheduled follow-up attendance among the 699 patients with a scheduled follow-up appointment. No significant associations were observed between last scheduled follow-up attendance and sex, age group, comorbidity, primary diagnosis group, medication prescription, adverse effects, drug class, or psychological testing (all p > 0.05).

Table 3.

Bivariate associations between study variables and last scheduled follow-up attendance (N = 699).

Variable Attended
n (%)
Did not attend
n (%)
χ² p Cramér's V
Sex Male 263 (55.4) 212 (44.6) 1.230a 0.267 0.042
Female 134 (59.8) 90 (40.2)
Age group 1–3 years 20 (50.0) 20 (50.0) 3.237a 0.357 0.068
4–6 years 90 (59.6) 61 (40.4)
7–11 years 157 (59.5) 107 (40.5)
12–18 years 130 (53.3) 114 (46.7)
Comorbidity Yes 261 (56.7) 199 (43.3) 0.005a 0.945 0.003
No 131 (56.5) 101 (43.5)
Primary diagnosis group ADHD 127 (57.2) 95 (42.8) 1.688a 0.890 0.049
Anxiety/Depression/ OCD disorders 111 (54.4) 93 (45.6)
Neurodevelopmental disorders 136 (57.9) 99 (42.1)
Mood and psychotic disorders 5 (71.4) 2 (28.6)
Other psychiatric disorders 7 (53.8) 6 (46.2)
No diagnosis 11 (64.7) 6 (35.3)
Medication prescribed Yes 356 (57.5) 263 (42.5) 0.722a 0.396 0.032
No 36 (52.2) 33 (47.8)
Adverse Effects Yes 110 (57.9) 80 (42.1) 0.080a 0.777 0.011
No 242 (56.7) 185 (43.3)
Drug class Monotherapy 144 (58.8) 101 (41.2) 1.259a 0.533 0.042
Polypharmacy/other 216 (56.5) 166 (43.5)
Non-pharmacological treatment 37 (51.4) 35 (48.6)
Psychological test performed Yes 197 (59.7) 133 (40.3) 1.984a 0.159 0.053
No 198 (54.4) 166 (45.6)

Pearson's chi-square test was used to compare categorical variables. Effect sizes are presented as Cramér's V. Statistical significance was defined as p < 0.05. OCD, Obsessive-Compulsive Disorder; SLD, Specific Learning Disorder; ASD, Autism Spectrum Disorder; Analytic denominators varied because of missing data, sex and age group, n = 699; comorbidity, n = 692; primary diagnosis group, n = 698; medication prescription, n = 688; adverse effects, n = 617; drug class, n = 699; and psychological testing, n = 694.

3.4. Comparison of reasons for missing the last follow-up appointment

Table 4 compares selected sociodemographic and treatment-related characteristics according to the documented reasons for missing the last scheduled follow-up appointment among the 302 non-attendees. Variables included in this analysis were selected based on their potential clinical relevance to treatment discontinuation and continuity of care. Among the variables examined, medication prescription status (χ² = 9.749, p = 0.008, Cramér’s V = 0.181) and drug class (χ² = 10.202, p = 0.037, Cramér’s V = 0.130) were significantly associated with the documented reason for non-attendance. Patients who were prescribed medication more frequently had treatment-related or practical/social reasons for non-attendance, whereas unspecified reasons were more common among patients who were not prescribed medication. Similarly, unspecified reasons were more frequent among patients receiving non-pharmacological treatment than among those receiving monotherapy or polypharmacy/other treatment. No statistically significant associations were observed for sex (p = 0.601), comorbidity (p = 0.702), or adverse effects (p = 0.862).

Table 4.

Comparison of reasons for missing the last follow-up appointment according to sociodemographic and treatment characteristics (N = 302).

Variables Treatment-related reasons Practical/
social barriers
Unspecified reasons χ² p Cramér's V
n (%) n (%) n (%)
Sex Female 13 (14.4) 45 (50.0) 32 (35.6) 1.020a 0.601 0.058
Male 22 (10.4) 111 (52.4) 79 (37.3)
Comorbidity Yes 25 (12.6) 103 (51.8) 71 (35.7) 0.707a 0.702 0.049
No 10 (9.9) 51 (50.5) 40 (39.6)
Medication prescribed Yes 32 (12.2) 144 (54.8) 87 (33.1) 9.749a 0.008 0.181
No 3 (9.1) 10 (30.3) 20 (60.6)
Adverse Effects Yes 10 (12.5) 45 (56.3) 25 (31.3) 0.297a 0.862 0.033
No 23 (12.4) 98 (53.0) 64 (34.6)
Drug class Monotherapy 14 (13.9) 56 (55.4) 31 (30.7) 10.202a 0.037 0.130
Polypharmacy/
other
18 (10.8) 89 (53.6) 59 (35.5)
Non-pharmacological treatment 3 (8.6) 11 (31.4) 21 (60.0)

Pearson's chi-square test was used to compare categorical variables. Effect sizes are presented as Cramér's V. Statistical significance was defined as p < 0.05. Analytic denominators varied because of missing data: sex, n = 302; comorbidity, n = 300; medication prescription status, n = 296; adverse effects, n = 265; and drug class, n = 302. Bold p-values indicate statistically significant results (p < 0.05)

4. Discussion

In this retrospective study, 841 children and adolescents receiving care at a tertiary child and adolescent mental health outpatient clinic were evaluated. Among the 699 patients with a scheduled follow-up appointment, 56.8% attended their last scheduled follow-up appointment. None of the demographic, clinical, or treatment-related variables examined were significantly associated with last scheduled follow-up attendance. Furthermore, among the 302 patients who missed their last scheduled follow-up appointment, both medication prescription status and drug class were significantly associated with the documented reason for non-attendance. Treatment-related reasons and practical/social barriers were more frequently documented among patients who were prescribed medication, whereas unspecified reasons were more frequent among those who were not prescribed medication. Similarly, unspecified reasons were more frequent among patients receiving non-pharmacological treatment than among those receiving monotherapy or polypharmacy/other treatment. No significant associations were observed between the documented reason for non-attendance and sex, comorbidity, or adverse effects. The present findings suggest that reasons for missed follow-up appointments may reflect multiple patient-, treatment-, and service-related factors rather than a single underlying cause. These findings are generally consistent with previous studies demonstrating that treatment discontinuation in child and adolescent mental health services is a multidimensional phenomenon. Consistent with previous systematic reviews, demographic and diagnostic characteristics alone may be insufficient to explain continuity of care. Previous research has highlighted the potential importance of treatment-related and service-related factors (4, 7). Nevertheless, a recent systematic review identified the quality of the therapeutic alliance, patient and family engagement, transparent communication, and alignment between treatment expectations and therapeutic approaches as key determinants of treatment adherence (7). In addition, service-level and clinician-related factors have been shown to play an important role in continuity of care (17), suggesting that healthcare service characteristics not evaluated in the present study may also influence follow-up behavior. Similarly, the high rates of early treatment discontinuation reported in tertiary child and adolescent mental health services highlight the need for service models that promote continuity of care, particularly following the initial assessment (15). Taken together, these findings suggest that missed follow-up appointments should be considered not only in relation to patient-level clinical characteristics but also within the broader context of the treatment process, patient and family engagement, and the organization of mental health services.

The finding that both medication prescription status and drug class were associated with the documented reasons for missing the last scheduled follow-up appointment supports the view that missed appointments are influenced by multiple interacting factors rather than a single determinant. A recent retrospective cohort study also reported that initiation of pharmacological treatment at the first psychiatric visit was associated with greater treatment retention (16). This may partly explain why patients receiving medication have more frequent contact with healthcare services, providing greater opportunities to communicate treatment-related concerns during follow-up. Recent systematic reviews have shown that missed appointments result from the interaction of multiple overlapping factors, including transportation difficulties, competing life events, limited flexibility in access to services, and patients’ perceptions that follow-up is unnecessary or no longer beneficial (18, 19). In this context, the classification of transportation problems, social events such as weddings or funerals, and financial difficulties as social reasons in the present study is consistent with the existing literature. Furthermore, the more frequent documentation of treatment-related or social reasons among patients who were prescribed medication may reflect their greater contact with healthcare services, resulting in more detailed documentation of the reasons for missed appointments in clinical records. In contrast, the higher proportion of unspecified reasons among patients who were not prescribed medication may be related to more limited contact with healthcare providers or incomplete documentation of the reasons for non-attendance. Similarly, the higher proportion of unspecified reasons among patients receiving non-pharmacological treatment compared with those receiving monotherapy or polypharmacy/other treatment may reflect differences in treatment pathways and patterns of contact with mental health services. Previous research has also demonstrated that continuity of care in child and adolescent mental health services is influenced not only by patient characteristics but also by the organization of healthcare services and the structure of the care pathway (20). In contrast, adverse effects were not significantly associated with the documented reasons for non-attendance in the present study. This finding differs from previous studies reporting that adverse effects may contribute to poorer medication adherence and more negative treatment attitudes among children and adolescents receiving psychiatric treatment (21). The discrepancy may be attributable to differences in sample characteristics, the retrospective nature of the clinical records, or the classification of reasons for missed appointments. The proportion of undocumented reasons for non-attendance may reflect documentation bias, as reasons for non-attendance may have been recorded more consistently in certain clinical situations than in others.

This study has several limitations. Owing to its retrospective design, the observed associations should not be interpreted as causal relationships. In addition, because the study relied on routinely collected clinical records, some variables may have been incompletely or inconsistently documented. The presence of undocumented reasons for missed follow-up appointments may have introduced documentation bias and may have limited the robustness and generalizability of the observed associations, as the recorded reasons may not accurately reflect the full spectrum of factors underlying missed appointments. Furthermore, the study was conducted at a single tertiary referral center, which may limit the generalizability of the findings to primary care settings or other mental health service providers. The study covered an 11-year period during which changes in clinical practice, service organization, and external events such as the COVID-19 pandemic may have influenced follow-up attendance. In addition, patients without a scheduled follow-up appointment were excluded from the attendance analysis because this outcome was not applicable to these patients. These temporal factors could not be evaluated separately and therefore may have affected the observed patterns of continuity of care. Important factors that may influence continuity of care, including socioeconomic status, family functioning, parental attitudes toward treatment, the therapeutic alliance, and access to mental health services, were not available in the medical records and therefore could not be evaluated. Previous studies have shown that family characteristics, parental mental health, socioeconomic disadvantage, accessibility of mental health services, travel distance, and organizational factors may also influence continuity of care and should be considered in future research (22, 23). Future multicenter prospective studies incorporating psychosocial and healthcare service–related factors, together with more comprehensive and standardized documentation of missed appointments, are warranted to provide a more comprehensive understanding of the determinants of continuity of care in child and adolescent mental health services.

From a clinical perspective, the findings of this study have important implications for outpatient child and adolescent mental health services. Rather than treating all missed appointments as a homogeneous phenomenon, routinely documenting and evaluating the reasons for non-attendance may provide valuable information for clinical decision-making. In particular, systematically distinguishing treatment-related reasons, practical or social barriers, and undocumented reasons for non-attendance may facilitate the development of tailored follow-up strategies and improve continuity of care. Systematic assessment of the reasons for missed appointments may therefore contribute to improving continuity of care and to the more effective organization and delivery of child and adolescent mental health services.

5. Conclusion

In this retrospective study of 841 children and adolescents receiving outpatient psychiatric care, no significant associations were observed between last scheduled follow-up attendance and the demographic, clinical, or treatment-related characteristics examined. Among patients who missed their last scheduled follow-up appointment, medication prescription status and drug class were significantly associated with the documented reason for non-attendance. No significant associations were observed between the documented reason for non-attendance and sex, comorbidity, or adverse effects. These findings emphasize the importance of routinely documenting and evaluating the reasons for missed appointments in clinical practice. Identifying the underlying causes of appointment non-attendance may help improve continuity of care and inform targeted strategies to enhance follow-up in child and adolescent mental health services.

Acknowledgments

The authors thank all healthcare professionals involved in maintaining the clinical records used in this study and acknowledge the support of the outpatient child and adolescent psychiatry clinic staff during the data collection process.

Funding Statement

The author(s) declared that financial support was not received for this work and/or its publication.

Footnotes

Edited by: Ricardo Gusmão, University of Porto, Portugal

Reviewed by: Gyula Sófi, Kertváros Pszichológiai Rendelő, Hungary

Asbjørn Steiro, Norwegian Directorate of Health, Norway

Data availability statement

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.

Ethics statement

The studies involving humans were approved by İnönü University Non-Interventional Clinical Research Ethics Committee. The studies were conducted in accordance with the local legislation and institutional requirements. The ethics committee/institutional review board waived the requirement of written informed consent for participation from the participants or the participants’ legal guardians/next of kin because this was a retrospective study based on routinely collected clinical records, the requirement for informed consent was waived by the ethics committee.

Author contributions

SS: Conceptualization, Data curation, Formal analysis, Methodology, Resources, Visualization, Writing – original draft, Writing – review & editing. DY: Data curation, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing.

Conflict of interest

The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Generative AI statement

The author(s) declared that generative AI was used in the creation of this manuscript. Portions of this manuscript were edited with the assistance of ChatGPT (OpenAI, GPT-5.5) to improve language, grammar, readability, and overall clarity. All scientific content, study design, data analysis, interpretation of the findings, and final responsibility for the manuscript remain solely with the authors. The authors reviewed and verified all AI-assisted content for accuracy, originality, and appropriate citation.

Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

References

  • 1. Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A. Prevalence and development of psychiatric disorders in childhood and adolescence. Arch Gen Psychiatry. (2003) 60:837–44. doi:  10.1001/archpsyc.60.8.837 [DOI] [PubMed] [Google Scholar]
  • 2. Faraone SV, Biederman J, Mick E. The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med. (2006) 36:159–65. doi:  10.1017/S003329170500471X [DOI] [PubMed] [Google Scholar]
  • 3. Sullivan MA, Rudnik-Levin F. Attention deficit/hyperactivity disorder and substance abuse: diagnostic and therapeutic considerations. Ann N Y Acad Sci. (2001) 931:251–70. doi:  10.1111/j.1749-6632.2001.tb05783.x [DOI] [PubMed] [Google Scholar]
  • 4. de Haan AM, Boon AE, de Jong JT, Hoeve M, Vermeiren RR. A meta-analytic review on treatment dropout in child and adolescent outpatient mental health care. Clin Psychol Rev. (2013) 33:698–711. doi:  10.1016/j.cpr.2013.04.005 [DOI] [PubMed] [Google Scholar]
  • 5. de Haan AM, Boon AE, de Jong JTVM, Vermeiren RRJM. A review of mental health treatment dropout by ethnic minority youth. Transcult Psychiatry. (2018) 55:3–30. doi:  10.1177/1363461517731702 [DOI] [PubMed] [Google Scholar]
  • 6. Reneses B, Escudero A, Tur N, Agüera-Ortiz L, Moreno DM, Saiz-Ruiz J, et al. The black hole of the transition process: dropout of care before transition age in adolescents. Eur Child Adolesc Psychiatry. (2023) 32:1285–95. doi:  10.1007/s00787-021-01939-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7. de Soet R, Vermeiren RRJM, Bansema CH, van Ewijk H, Nijland L, Nooteboom LA. Drop-out and ineffective treatment in youth with severe and enduring mental health problems: a systematic review. Eur Child Adolesc Psychiatry. (2024) 33:3305–19. doi:  10.1007/s00787-023-02182-z [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8. Pelkonen M, Marttunen M, Laippala P, Lönnqvist J. Factors associated with early dropout from adolescent psychiatric outpatient treatment. J Am Acad Child Adolesc Psychiatry. (2000) 39:329–36. doi:  10.1097/00004583-200003000-00015 [DOI] [PubMed] [Google Scholar]
  • 9. Seidler ZE, Rice SM, Dhillon HM, Cotton SM, Telford NR, McEachran J, et al. Patterns of youth mental health service use and discontinuation: population data from Australia's Headspace model of care. Psychiatr Serv. (2020) 71:1104–13. doi:  10.1176/appi.ps.201900491 [DOI] [PubMed] [Google Scholar]
  • 10. Libowitz MR, Nurmi EL. The burden of antipsychotic-induced weight gain and metabolic syndrome in children. Front Psychiatry. (2021) 12:623681. doi:  10.3389/fpsyt.2021.623681 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11. Pogge DL, Singer MB, Harvey PD. Rates and predictors of adherence with atypical antipsychotic medication: a follow-up study of adolescent inpatients. J Child Adolesc Psychopharmacol. (2005) 15:901–12. doi:  10.1089/cap.2005.15.901 [DOI] [PubMed] [Google Scholar]
  • 12. De R, Smith ECC, Navagnanavel J, Au E, Maksyutynska K, Papoulias M, et al. The impact of weight gain on antipsychotic nonadherence or discontinuation: a systematic review and meta-analysis. Acta Psychiatr Scand. (2025) 151:109–26. doi:  10.1111/acps.13758 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13. Mann CJ. Observational research methods. Research design II: cohort, cross sectional, and case-control studies. Emerg Med J. (2003) 20:54–60. doi:  10.1136/emj.20.1.54 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14. von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. PloS Med. (2007) 4:e296. doi:  10.1371/journal.pmed.0040296 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 15. Sharma A, Raju V, Shah R, Pritpal, Grover S. Dropout rates among patients attending child and adolescent psychiatry services of a tertiary care center: a retrospective study from North India. J Indian Assoc Child Adolesc Ment Health. (2021) 17:100–14. doi:  10.1177/0973134220210407 [DOI] [Google Scholar]
  • 16. Sasaki Y, Usami M, Hakosima Y, Inazaki K, Mizumoto Y, Ito M, et al. Factors influencing treatment dropout among child and adolescent psychiatric patients: a survival analysis. J Clin Psychol Med Settings. (2026). doi:  10.1007/s10880-026-10159-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17. Edbrooke-Childs J, Boehnke JR, Zamperoni V, Calderon A, Whale A. Service- and practitioner-level variation in non-consensual dropout from child mental health services. Eur Child Adolesc Psychiatry. (2020) 29:929–34. doi:  10.1007/s00787-019-01405-6 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18. Lindsay C, Baruffati D, Mackenzie M, Ellis DA, Major M, O'Donnell CA, et al. Understanding the causes of missingness in primary care: a realist review. BMC Med. (2024) 22:235. doi:  10.1186/s12916-024-03456-2 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 19. Alturbag M. Factors and reasons associated with appointment non-attendance in hospitals: a narrative review. Cureus. (2024) 16:e58594. doi:  10.7759/cureus.58594 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20. Aguilar Silvan Y, Fortuna LR, Spencer AE, Ng LC. Engagement in child psychiatry department appointments: an analysis of electronic medical records in one safety-net hospital in New England, USA. J Health Serv Res Policy. (2025) 30:79–88. doi:  10.1177/13558196241311712 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21. Bayraktar İ, Yalçın N, Nalbant K, Kültür EÇ, Demirkan K. Medication adherence and attitudes in adolescent psychiatry: key influences. Clin Child Psychol Psychiatry. (2025) 30:516–28. doi:  10.1177/13591045251316607 [DOI] [PubMed] [Google Scholar]
  • 22. Packness A, Waldorff FB, Christensen RD, Hastrup LH, Simonsen E, Vestergaard M, et al. Impact of socioeconomic position and distance on mental health care utilization: a nationwide Danish follow-up study. Soc Psychiatry Psychiatr Epidemiol. (2017) 52:1405–13. doi:  10.1007/s00127-017-1437-2 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23. Packness A, Halling A, Simonsen E, Waldorff FB, Hastrup LH. Are perceived barriers to accessing mental healthcare associated with socioeconomic position among individuals with symptoms of depression? Questionnaire results from the Lolland-Falster Health Study, a rural Danish population study. BMJ Open. (2019) 9:e023844. doi:  10.1136/bmjopen-2018-023844 [DOI] [PMC free article] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Data Availability Statement

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.


Articles from Frontiers in Psychiatry are provided here courtesy of Frontiers Media SA

RESOURCES