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Transactions of the American Ophthalmological Society logoLink to Transactions of the American Ophthalmological Society
. 2002;100:79–84.

Surgical approaches to the management of epithelial cysts.

Julia A Haller 1, Walter J Stark 1, Amar Azab 1, Robert W Thomsen 1, John D Gottsch 1
PMCID: PMC1358950  PMID: 12545681

Abstract

PURPOSE: The purpose of this study was to review management strategies for treatment of epithelial cysts. STUDY DESIGN: Retrospective consecutive interventional case series. METHODS: Charts of patients treated for epithelial ingrowth over a 10-year period by a single surgeon (J.A.H.) were reviewed. Cases of epithelial cysts were identified and the following data were recorded: details of ocular history, preoperative and postoperative visual acuity, intraocular pressure (IOP), ocular examination findings, type of surgical intervention, and details of subsequent procedures performed. RESULTS: Seven eyes with epithelial cysts were identified. Patients ranged in age from 1 1/2 years to 53 years at presentation. Three patients were children. Four cysts were due to trauma, one was presumably congenital, one developed after corneal perforation in an eye with Terrien's marginal degeneration, and one developed after penetrating keratoplasty. Three patients were treated with vitrectomy, en bloc resection of the cyst and associated tissue, fluid-air exchange, and cryotherapy. Four patients were treated with conservative strategy consisting of cyst aspiration (three cases) or local excision (one "keratin pearl" cyst) and endolaser photocoagulation of the collapsed cyst wall or base. In all cases, the epithelial tissue was successfully eradicated; one case required a second excision (follow-up, 9 months to 78 months; mean, 45 months). Two eyes required subsequent surgery for elevated IOP, two for cataract extraction, and one for a second penetrating keratoplasty. Final visual acuity ranged from 20/20 to hand motions, depending on associated ocular damage. Best visual results were obtained in the more conservatively managed eyes. CONCLUSION: Epithelial cysts can be managed conservatively in selected patients with good results. This strategy may be particularly useful in children, in whom preservation of the lens, iris, and other structures may facilitate amblyopia management.

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Selected References

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  1. Bruner W. E., Michels R. G., Stark W. J., Maumenee A. E. Management of epithelial cysts of the anterior chamber. Ophthalmic Surg. 1981 Apr;12(4):279–285. [PubMed] [Google Scholar]
  2. Cleasby G. W. Photocoagulation of iris-ciliary body epithelial cysts. Trans Am Acad Ophthalmol Otolaryngol. 1971 May-Jun;75(3):638–642. [PubMed] [Google Scholar]
  3. Ferry A. P., Naghdi M. R. Cryosurgical removal of epithelial cyst of iris and anterior chamber. Arch Ophthalmol. 1967 Jan;77(1):86–87. doi: 10.1001/archopht.1967.00980020088019. [DOI] [PubMed] [Google Scholar]
  4. Forster R. K. Corneoscleral block excision of postoperative anterior chamber cysts. Trans Am Ophthalmol Soc. 1995;93:83–104. [PMC free article] [PubMed] [Google Scholar]
  5. HOGAN M. J., GOODNER E. K. Surgical treatment of epithelial cysts of the anterior chamber. Arch Ophthalmol. 1960 Aug;64:286–291. doi: 10.1001/archopht.1960.01840010288016. [DOI] [PubMed] [Google Scholar]
  6. Harbin T. S., Jr, Maumenee A. E. Epithelial downgrowth after surgery for epithelial cyst. Am J Ophthalmol. 1974 Jul;78(1):1–4. doi: 10.1016/0002-9394(74)90002-6. [DOI] [PubMed] [Google Scholar]
  7. KENNEDY P. J. Treatment of cysts of the iris with electrolysis. AMA Arch Ophthalmol. 1956 Apr;55(4):522–525. doi: 10.1001/archopht.1956.00930030526011. [DOI] [PubMed] [Google Scholar]
  8. MAUMENEE A. E., SHANNON C. R. Epithelial invasion of the anterior chamber. Am J Ophthalmol. 1956 Jun;41(6):929–942. doi: 10.1016/0002-9394(56)91039-x. [DOI] [PubMed] [Google Scholar]
  9. Maumenee A. E., Paton D., Morse P. H., Butner R. Review of 40 histologically proven cases of epithelial downgrowth following cataract extraction and suggested surgical management. Am J Ophthalmol. 1970 Apr;69(4):598–603. doi: 10.1016/0002-9394(70)91626-0. [DOI] [PubMed] [Google Scholar]
  10. Naumann G. O., Rummelt V. Block excision of cystic and diffuse epithelial ingrowth of the anterior chamber. Report on 32 consecutive patients. Arch Ophthalmol. 1992 Feb;110(2):223–227. doi: 10.1001/archopht.1992.01080140079031. [DOI] [PubMed] [Google Scholar]
  11. Okun E., Mandell A. Photocoagulation as a treatment of epithelial implantation cysts following cataract surgery. Trans Am Ophthalmol Soc. 1974;72:170–183. [PMC free article] [PubMed] [Google Scholar]
  12. Orlin S. E., Raber I. M., Laibson P. R., Shields C. L., Brucker A. J. Epithelial downgrowth following the removal of iris inclusion cysts. Ophthalmic Surg. 1991 Jun;22(6):330–335. [PubMed] [Google Scholar]
  13. Roy F. H., Hanna C. Spontaneous congenital iris cyst. Am J Ophthalmol. 1971 Jul 30;72(1):97–108. doi: 10.1016/0002-9394(71)91596-0. [DOI] [PubMed] [Google Scholar]
  14. Scholz R. T., Kelley J. S. Argon laser photocoagulation treatment of iris cysts following penetrating keratoplasty. Arch Ophthalmol. 1982 Jun;100(6):926–927. doi: 10.1001/archopht.1982.01030030934006. [DOI] [PubMed] [Google Scholar]
  15. Shields J. A., Shields C. L., Lois N., Mercado G. Iris cysts in children: classification, incidence, and management. The 1998 Torrence A Makley Jr Lecture. Br J Ophthalmol. 1999 Mar;83(3):334–338. doi: 10.1136/bjo.83.3.334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Stark W. J., Michels R. G., Maumenee A. E., Cupples H. Surgical management of epithelial ingrowth. Am J Ophthalmol. 1978 Jun;85(6):772–780. doi: 10.1016/s0002-9394(14)78104-8. [DOI] [PubMed] [Google Scholar]
  17. Sugar H. S. Further experience with posterior lamellar resection of the cornea for epithelial implantation cyst. Am J Ophthalmol. 1967 Aug;64(2):291–299. doi: 10.1016/0002-9394(67)92527-5. [DOI] [PubMed] [Google Scholar]
  18. Tsai J. C., Arrindell E. L., O'Day D. M. Needle aspiration and endodiathermy treatment of epithelial inclusion cyst of the iris. Am J Ophthalmol. 2001 Feb;131(2):263–265. doi: 10.1016/s0002-9394(00)00707-8. [DOI] [PubMed] [Google Scholar]
  19. VAIL D. Treatment of cysts of the iris with diathermy coagulation. Trans Am Ophthalmol Soc. 1953;51:371–383. [PMC free article] [PubMed] [Google Scholar]
  20. WILSON W. IRIS CYST TREATED CY ELECTROLYSIS. Br J Ophthalmol. 1964 Jan;48:45–49. doi: 10.1136/bjo.48.1.45. [DOI] [PMC free article] [PubMed] [Google Scholar]

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