Skip to main content
NCBI home page
The Journal of Physiology logoLink to The Journal of Physiology
. 1963 Oct;168(3):564–583. doi: 10.1113/jphysiol.1963.sp007208

The metabolism of free fatty acids and chylomicron triglycerides by the isolated perfused liver of the rat

B Morris
PMCID: PMC1359440  PMID: 14067944

Full text

PDF
564

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BORGSTROM B. Investigation on lipid separation methods. Separation of cholesterol esters, glycerides and free fatty acids. Acta Physiol Scand. 1952 Jun 6;25(2-3):111–119. doi: 10.1111/j.1748-1716.1952.tb00863.x. [DOI] [PubMed] [Google Scholar]
  2. BORGSTROM B., JORDAN P. Metabolism of chylomicron glyceride as studied by C14-glycerol-C14-palmitic acid labeled chylomicrons. Acta Soc Med Ups. 1959;64:185–193. [PubMed] [Google Scholar]
  3. BRAGDON J. H., GORDON R. S., Jr Tissue distribution of C14 after the intravenous injection of labeled chylomicrons and unesterified fatty acids in the rat. J Clin Invest. 1958 Apr;37(4):574–578. doi: 10.1172/JCI103640. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CHAIKOFF I. L., GOLDMAN D. S., BROWN G. W., Jr, DAUBEN W. G., GEE M. Acetoacetate formation in liver. I. From palmitic acid-1-C14, 5-C14 and 11-C14. J Biol Chem. 1951 May;190(1):229–240. [PubMed] [Google Scholar]
  5. DITTMER J. C., HANAHAN D. J. Biochemistry of long chain fatty acids. I. General observations. J Biol Chem. 1959 Aug;234(8):1976–1982. [PubMed] [Google Scholar]
  6. DOLE V. P. A relation between non-esterified fatty acids in plasma and the metabolism of glucose. J Clin Invest. 1956 Feb;35(2):150–154. doi: 10.1172/JCI103259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FELLER D. D., STRISOWER E. H., CHAIKOFF I. L. Turnover and oxidation of body glucose in normal and alloxan-diabetic rats. J Biol Chem. 1950 Dec;187(2):571–588. [PubMed] [Google Scholar]
  8. FOLCH J., LEES M., SLOANE STANLEY G. H. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957 May;226(1):497–509. [PubMed] [Google Scholar]
  9. FREDRICKSON D. S., HAVEL R. J. The metabolism of chylomicra. I. The removal of palmitic acid-1-C14 labeled chylomicra from dog plasma. J Clin Invest. 1956 Sep;35(9):1025–1032. doi: 10.1172/JCI103348. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FRENCH J. E., MORRIS B. The removal of 14C-labelled chylomicron fat from the circulation in rats. J Physiol. 1957 Sep 30;138(2):326–339. doi: 10.1113/jphysiol.1957.sp005854. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. FRENCH J. E., MORRIS B. The tissue distribution and oxidation of 14C-labelled chylomicron fat injected intravenously in rats. J Physiol. 1958 Feb 17;140(2):262–271. doi: 10.1113/jphysiol.1958.sp005932. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HAFT D. E., MILLER L. L. Alloxan diabetes and demonstrated direct action of insulin on metabolism of isolated perfused rat liver. Am J Physiol. 1958 Jan;192(1):33–42. doi: 10.1152/ajplegacy.1957.192.1.33. [DOI] [PubMed] [Google Scholar]
  13. HEIMBERG M., WEINSTEIN I., KLAUSNER H., WATKINS M. L. Release and uptake of triglycerides by isolated perfused rat liver. Am J Physiol. 1962 Feb;202:353–358. doi: 10.1152/ajplegacy.1962.202.2.353. [DOI] [PubMed] [Google Scholar]
  14. HILLYARD L. A., CORNELIUS C. E., CHAIKOFF I. L. Removal by the isolated rat liver of palmitate-1-C14 bound to albumin and of palmitate-1-C14 and cholesterol-4-C14 in chylomicrons from perfusion fluid. J Biol Chem. 1959 Sep;234:2240–2245. [PubMed] [Google Scholar]
  15. HIRSCH J., AHRENS E. H., Jr The separation of complex lipide mixtures by the use of silicic acid chromatography. J Biol Chem. 1958 Aug;233(2):311–20. [PubMed] [Google Scholar]
  16. KAY R. E., ENTENMAN C. The synthesis of "chylomicronlike" bodies and maintenance of normal blood sugar levels by the isolated, perfused rat liver. J Biol Chem. 1961 Apr;236:1006–1012. [PubMed] [Google Scholar]
  17. LAURELL S. Recycling of intravenously injected palmitic acid-1-C14 as esterified fatty acid in the plasma of rats and turnover rate of plasma triglycerides. Acta Physiol Scand. 1959 Nov 15;47:218–232. doi: 10.1111/j.1748-1716.1960.tb00072.x. [DOI] [PubMed] [Google Scholar]
  18. MORRIS B., FRENCH J. E. The uptake and metabolism of 14C labelled chylomicron fat by the isolated perfused liver of the rat. Q J Exp Physiol Cogn Med Sci. 1958 Apr;43(2):180–188. doi: 10.1113/expphysiol.1958.sp001315. [DOI] [PubMed] [Google Scholar]
  19. MORRIS B. SOME FACTORS AFFECTING THE METABOLISM OF FREE FATTY ACIDS AND CHYLOMICRON TRIGLYCERIDES BY THE PERFUSED RAT'S LIVER. J Physiol. 1963 Oct;168:584–598. doi: 10.1113/jphysiol.1963.sp007209. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. MORRIS B. Some observations on the production of bile by the isolated perfused liver of the rat. Aust J Exp Biol Med Sci. 1960 Apr;38:99–110. doi: 10.1038/icb.1960.11. [DOI] [PubMed] [Google Scholar]
  21. ROBINSON D. S., FRENCH J. E. The heparin clearing reaction and fat transport. Q J Exp Physiol Cogn Med Sci. 1957 Apr;42(2):151–163. doi: 10.1113/expphysiol.1957.sp001246. [DOI] [PubMed] [Google Scholar]
  22. SIMPSON-MORGAN M. W., MORRIS B. A comparison of the metabolism of palmitic, oleic and linoleic acids incorporated into chylomicron triglycerides. Aust J Exp Biol Med Sci. 1962 Dec;40:445–453. doi: 10.1038/icb.1962.49. [DOI] [PubMed] [Google Scholar]
  23. STEIN Y., SHAPIRO B. Assimilation and dissimilation of fatty acids by the rat liver. Am J Physiol. 1959 Jun;196(6):1238–1241. doi: 10.1152/ajplegacy.1959.196.6.1238. [DOI] [PubMed] [Google Scholar]
  24. STERN I., SHAPIRO B. A rapid and simple method for the determination of esterified fatty acids and for total fatty acids in blood. J Clin Pathol. 1953 May;6(2):158–160. doi: 10.1136/jcp.6.2.158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. WERK E. E., Jr, McPHERSON H. T., HAMRICK L. W., Jr, MYERS J. D., ENGEL F. L. Studies on ketone metabolism in man. I. A method for the quantitative estimation of splanchnic ketone production. J Clin Invest. 1955 Aug;34(8):1256–1267. doi: 10.1172/JCI103172. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES