Skip to main content
PMC home page
The Journal of Physiology logoLink to The Journal of Physiology
. 1962 Oct;163(3):423–435. doi: 10.1113/jphysiol.1962.sp006987

The penetration of urea into the central nervous system at high blood levels

M W B Bradbury, R V Coxon
PMCID: PMC1359717  PMID: 14014805

Full text

PDF
423

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERING E. A., Jr Water exchange of central nervous system and cerebrospinal fluid. J Neurosurg. 1952 May;9(3):275–287. doi: 10.3171/jns.1952.9.3.0275. [DOI] [PubMed] [Google Scholar]
  2. COXON R. V., ROBINSON R. J. Movements of radioactive carbon dioxide within the animal body during oxidation of 14C-labelled substances. J Physiol. 1959 Oct;147:487–510. doi: 10.1113/jphysiol.1959.sp006258. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Conway E. J., Fitzgerald O. Diffusion relations of urea, inulin and chloride in some mammalian tissues. J Physiol. 1942 Jun 2;101(1):86–105. doi: 10.1113/jphysiol.1942.sp003968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. DAVSON H., SPAZIANI E. The blood-brain barrier and the extracellular space of brain. J Physiol. 1959 Dec;149:135–143. doi: 10.1113/jphysiol.1959.sp006330. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. GROLLMAN E. F., GROLLMAN A. Toxicity of urea and its role in the pathogenesis of uremia. J Clin Invest. 1959 May;38(5):749–754. doi: 10.1172/JCI103855. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. JAVID M., SETTLAGE P. Effect of urea on cerebrospinal fluid pressure in human subjects; preliminary report. J Am Med Assoc. 1956 Mar 17;160(11):943–949. doi: 10.1001/jama.1956.02960460021006. [DOI] [PubMed] [Google Scholar]
  7. McCANCE R. A., WIDDOWSON E. M. A method of breaking down the body weights of living persons into terms of extracellular fluid, cell mass and fat, and some applications of it to physiology and medicine. Proc R Soc Lond B Biol Sci. 1951 Feb;138(890):115–130. doi: 10.1098/rspb.1951.0010. [DOI] [PubMed] [Google Scholar]
  8. RENKIN E. M. Exchangeability of tissue potassium in skeletal muscle. Am J Physiol. 1959 Dec;197:1211–1215. doi: 10.1152/ajplegacy.1959.197.6.1211. [DOI] [PubMed] [Google Scholar]
  9. ROBERTSON J. S. Theory and use of tracers in determining transfer rates in biological systems. Physiol Rev. 1957 Apr;37(2):133–154. doi: 10.1152/physrev.1957.37.2.133. [DOI] [PubMed] [Google Scholar]
  10. ROSOMOFF H. L. Method for simultaneous quantitative estimation of intracranial contents. J Appl Physiol. 1961 Mar;16:395–396. doi: 10.1152/jappl.1961.16.2.395. [DOI] [PubMed] [Google Scholar]
  11. SCHOOLAR J. C., BARLOW C. F., ROTH L. J. The penetration of carbon-14 urea into cerebrospinal fluid and various areas of the cat brain. J Neuropathol Exp Neurol. 1960 Apr;19:216–227. doi: 10.1097/00005072-196004000-00003. [DOI] [PubMed] [Google Scholar]
  12. SPORN M. B., DINGMAN W., DEFALCO A., DAVIES R. K. The synthesis of urea in the living rat brain. J Neurochem. 1959 Dec;5:62–67. doi: 10.1111/j.1471-4159.1959.tb13333.x. [DOI] [PubMed] [Google Scholar]
  13. STUBBS J., PENNYBACKER J. Reduction of intracranial pressure with hypertonic urea. Lancet. 1960 May 21;1(7134):1094–1097. doi: 10.1016/s0140-6736(60)90983-1. [DOI] [PubMed] [Google Scholar]
  14. VERNEY E. B. Water diuresis. Ir J Med Sci. 1954 Sep;(345):378–402. [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES