Versican isoforms modulate expression and function of nicotinic acetylcholine receptors

In this article, an image in Figure 2A was uploaded with an error. We have now used another group of results generated at the same time to replace the original image. We sincerely apologize for this oversight and any confusion it may have caused. The corrected images Figure 2 is shown below.

Figure 2.

Versican alters the expression of nicotinic receptors. A. PC12 cells stably transfected with vector or V1 and V2 constructs were incubated with NGF (50 ng/ml). Four days after treatment photographs of differentiation were acquired. B. Western blot analyses of AChR subunits α3, α4, α7 and α2 in the presence or absence of NGF. Expression of α3 and α7 was up-regulated by V1- and V2-transfection, while expression of α4 was down-regulated. In the presence of NGF, expression of α3 and α4 exhibited complementary patterns. C. The intensities of the protein bands were scanned, and the densitometry results were semiquantified (n = 3, *P< 0.05).