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MTII sensitivity (n = 12) expressed as reduction in 12-h food intake after i3cv MTII administration relative to saline (%Δ 12h-FI) but not leptin sensitivity (data not shown) before the HED exposure was significantly inversely correlated to CRH labeling (A) and [125I]NDP-MSH binding (B) in the PVN after the HED exposure.
