Skip to main content
PLOS One logoLink to PLOS One
. 2026 Sep 25;21(9):e0358482. doi: 10.1371/journal.pone.0358482

Eastern African expressions of suffering: A new Cultural Scripts of Trauma Inventory

Celestin Mutuyimana 1,2,*, Andreas Maercker 1
Editor: Inga Schalinski3
PMCID: PMC13614634  PMID: 42789603

Abstract

Introduction

Many people who have experienced trauma feel that PTSD criteria do not describe their experiences. They report culturally specific symptoms, in our new theory referred to as Cultural Scripts of Trauma, yet no study has systematically mapped these experiences or developed tools to measure them.

Objectives

This study aims to map cultural scripts of trauma suffering and to develop and validate the Cultural Scripts of Trauma Inventory (CSTI) across Eastern African countries, including Rwanda, Uganda, Tanzania, and Kenya.

Methods

A qualitative study involving 115 participants across nine focus groups of trauma survivors and experts was conducted to map the main cultural scripts of trauma experiences and generate initial pool of items. This was followed by a quantitative validation study involving 1,208 participants from Rwanda, Uganda, Tanzania, and Kenya. In an online survey, participants completed the pre-CSTI and additional measures for convergent and divergent validity, such as the International Trauma Questionnaire, Clinical Aspects of Historical Trauma, Purpose in Life Questionnaire, Subjective Vitality, and General Self-Efficacy.

Results

The results yield 71 Cultural Scripts of Trauma Sufferings (CSTs). The confirmatory factor analysis confirms 15 most relevant CSTs regrouped in five factors such as cognitive, body related, frame of mind, meaning disruption and family stress demonstrating excellent model fit. Those constitute 15 item-inventory that showed strong overall reliability and validity. Additionally, the model exhibited configural, metric, and partial scalar invariance, confirming its consistency across various groups.

Conclusion

This study is advancing culturally informed diagnosis and treatment of post traumatic sequelae by identification of culturally specific post trauma suffering and development and validation of CSTI in East African countries. It provides clinicians and researchers with a resource to adopt a model of beyond and including PTSD by offering a deeper understanding of post-traumatic stress in diverse cultural contexts.

Introduction

Globally, over 70% of people are exposed to a traumatic event; however, only about 3.9% meet the criteria for Post-Traumatic Stress Disorder (PTSD) [1,2]. In Sub Saharan Africa more than 80% of the population have faced a series of cumulative, collective, and repetitive traumatic experiences [3,4]. As result around 15% are suffering from PTSD and Complex PTSD (CPTSD) [5,6]. However, help-seeking behavior among trauma survivors remains low despite the high prevalence of trauma related disorders [7,8]. A crucial issue is that survivors, in this context, often fail to recognize their experiences within the established symptom pattern of PTSD [9,10]. For example survivors in East Africa suffered from feeling of unspeakable sufferings, body pains, mistrust, bitterness and heart wounds [11]. Survivors in Namibia perceived their suffering as something standing inside them [12].These forms of suffering was conceptualized in a new theoretical framework as Cultural Scripts of Trauma (CST) [10,13–15].

CST is defined as the set of culturally specific post-traumatic symptoms that are systematically sequenced and causally interconnected [16]. These symptoms are shaped and intensified by cultural values, norms, and beliefs [9]. CSTs also vary across cultures, with certain symptoms salient in one country but not in another [14]. For example, research has found that among East African populations, mistrust, body-related symptoms, and family stress are particularly prominent, whereas in Swiss samples, the urge to function and perform is more salient. Cultural values also differ: in Switzerland, symptoms are more often related to the urge to hide and endure suffering, while in East African contexts, they are more closely associated with the suppression of suffering, concerns about community reputation, and Christian beliefs [10,11,17]. CST complements standardized trauma diagnosis by capturing culture-specific symptoms often not included in ICD and DSM criteria.

The DSM introduced the Cultural Concepts of Distress (CCD) framework to improve recognition of culturally shaped expressions of psychological suffering, including cultural syndromes, idioms of distress, and explanatory models. Similarly, ICD-11 acknowledged the importance of cultural context in the experience and expression of trauma-related disorders, including PTSD and complex PTSD. However, these frameworks do not fully capture how trauma survivors experience, interpret, and express traumatic suffering within specific sociocultural contexts. CST differs from idioms of distress and CCD in several important ways. Idioms of distress generally refer to culturally specific expressions or ways of communicating suffering, such as local metaphors or commonly used phrases [18]. Therefore, idioms of distress are not actual disorders and not permanent but rather reflect the way a community interprets symptoms through semantic language [19,20].

For example, Baksbat in Cambodia has been linked to PTSD in some research and has been interpreted by many scholars as a disorder. However, a study involving people with lived experience in Cambodia has shown that Baksbat is a normal response in their context, understood as an expression of fear of various threats, particularly fear related to political expression, and it does not require medical treatment. The authors argue that Baksbat has been pathologized without sufficient justification [19]. Similarly, in Rwanda, the concept of Ihahamuka, although used for many years, was discontinued about a decade ago because it was deemed pejorative, as it was also used to describe cows with mental disturbances. The term Ihahamuka was replaced by Ihungabana, which referred to the displacement of certain elements in a person's psychological functioning. This term was later replaced by Ibikomere, meaning “heart wound” and Ibikomere is not a disorder but a way of expressing suffering (Mutuyimana & Maercker, 2020).

CCD, in turn, represent a broader category that includes not only idioms, but also cultural syndromes, explanatory models, and shared experiences recognized within a given cultural context [21]. In many studies, idioms of distress, cultural syndromes, and CCD are used interchangeably, which creates conceptual ambiguity and limits their practical usability [20,22]. This lack of clarity is further reflected in clinical practice, where limited interventions are developed specifically to address idioms of distress, as they are typically interpreted as surface-level expressions of underlying suffering rather than as clinically meaningful disorders.

Moreover, not all idioms of distress or CCD are inherently related to trauma; they may reflect a wide range of psychosocial difficulties. For example, susto in Latin America is often linked to spiritual disruption and has been described in three syndromic forms: one resembling depression, another somatic disorders, and a third related to PTSD [23]. As a result, trauma-specific symptoms that are culturally shaped may be overlooked or misinterpreted. This can lead to the underdiagnosis of culturally specific post-traumatic symptoms, as existing frameworks may fail to adequately capture how trauma manifests across different cultural contexts.

The CST approach addresses this gap. CST aims to complement universal diagnostic frameworks such as PTSD and CPTSD. While these models have demonstrated cross-cultural validity, they do not capture the full range of trauma-related experiences [14]. Based on that, CST highlights that trauma symptoms are not universally distributed or equally salient across cultures. In some contexts, culturally specific symptoms may have greater centrality and impact on individuals’ functioning than those emphasized in PTSD or CPTSD criteria. By advancing CST, this approach contributes a new layer to trauma theory: it moves beyond universal symptom lists toward understanding trauma as a culturally patterned, dynamic system of interconnected experiences. This has important implications for diagnosis, as well as for developing more culturally responsive and effective interventions.

Unlike the identified salient symptoms of PTSD and CPTSD, which emphasize a limited set of trauma sequelae derived largely from Western contexts [24] the cultural scripts of trauma sufferings and their corresponding measurements have yet to be systematically established. The absence of psychological measures for cultural scripts of trauma sufferings leads to an underestimation of the prevalence of posttraumatic disorders in highly traumatized populations. A cross cultural research have highlighted a paradox in the global distribution of trauma-related mental health issues, where individuals exposed to higher levels of traumatic events often exhibit fewer PTSD symptoms compared to those with less exposure [25]. This paradox does not imply that these individuals are not suffering, but rather that they may be experiencing other culturally specific symptoms that require special attention and recognition [26]. This gap carries significant implications for the lives of trauma survivors, as well as for their access to and utilization of mental health services.

The aim of this study is to map the cultural scripts of trauma experiences and to develop and validate the Cultural Scripts of Trauma Inventory (CSTI) across Eastern African countries, including Rwanda, Uganda, Tanzania, and Kenya. This study will assist researchers and clinicians in identifying not only standardized symptoms of PTSD but also culturally specific manifestations of trauma. By prioritizing the voices of individuals with lived experiences, the study ensures that their full experiences are captured. Once recognized by mental health practitioners, trauma survivors are more likely to trust and engage with mental health services. As a result, this approach has the potential to reduce the prevalence of post-traumatic sequelae and improve overall mental health outcomes.

Materials and methods

Qualitative study

Interview protocol guide.

The interview guide was developed basing on existing literature on trauma and cultural expressions of distress, as described in Cultural Script of Trauma (CST) (See S1 File). It included open-ended questions exploring the types of traumatic experiences, the symptoms or changes following these events, and how participants understood and related these symptoms to their cultural values and beliefs. For mental health practitioners and spiritual or traditional healers, the same questions were used, focusing on how they observe these experiences and symptoms in their clients.

Data collection procedure.

The study recruited adult trauma survivors and trauma experts from four countries: Rwanda, Uganda, Tanzania, and Kenya. The inclusion criteria for trauma survivors required them to experience trauma-related symptoms, regardless of whether they were receiving psychotherapeutic treatment, and to perceive themselves as fully connected to their cultural values, norms, and beliefs. Participants experiencing a mental health crisis or with psychotic disorders were excluded. Trauma survivors were recruited with the assistance of local NGOs working with trauma survivors or through psychotherapists. Trauma experts included psychotherapists, medical doctors, psychiatric nurses, and social workers who had experience of supporting trauma survivors. Additionally, traditional and spiritual healers who had provided care to trauma patients were also recruited. Participants were brought together in focus group discussions depending on their group: experts or trauma survivors. In Rwanda and Kenya, the discussions were conducted in person, while in the other countries, they were held in person or online via Zoom. Trauma survivors were asked to describe their post-traumatic stress experiences, whereas trauma experts discussed the experiences of their patients. Participants were also asked to explain how their sufferings or the sufferings of their patients are connected to the cultural values, norms, and beliefs in their communities. Each focus group session lasted between 2 and 2.5 hours and was audio recorded for analysis and or written in case of trust issue for recording. The interviews were conducted by the first author together with a local psychologist in each country. They were carried out in the participants’ preferred languages: Kinyarwanda in Rwanda; English in Uganda; and both English and Swahili in Kenya and Tanzania.

Qualitative data analysis.

Data were analyzed using thematic analysis frameworks [27] using MAXQDA. First, all transcribed and written data were cross-checked by two project members to ensure accuracy. Next, the qualitative material was independently coded by four coders focusing on recurring culturally specific trauma expressions and their meanings. The guiding questions for coders were: What post-traumatic expressions or changes are reported by participants, and which dimensions of cultural trauma scripts do they belong to? What item can be derived from those changes/symptoms mentioned? (See S2 File). Interviews conducted in Kinyarwanda and Swahili were coded in the original languages by local coders fluent in those languages to preserve cultural and linguistic nuances, and the resulting codes were later translated into English. Interviews conducted in English were independently coded by two researchers and reviewed by a local coder to ensure contextual accuracy. Following the initial coding process, the first author reviewed all codes in collaboration with a local psychologist. Any discrepancies were discussed until consensus was reached, resulting in a finalized and culturally validated items

Item content validity assessment.

The results yield initial pool of 98 items after removing redundant, irrelevant, and overlapping content, and evaluating items for clarity, and cultural relevance across sites. A pilot testing phase with 5 people in each country assessed item comprehensibility and cultural relevance. Their results indicated that all items were deemed resonant. The items in Kinyarwanda and Swahili were translated into English using forward and backward translation procedures. The final English version, along with the corresponding original-language items, was sent to eight experts from Rwanda, Kenya, Tanzania, and Uganda. This expert review led to the removal of 27 items (10 redundant, 12 unclear, and 5 with a Content Validity Index below 0.60). The remaining 71 items demonstrated strong content validity, with CVIs ranging between 0.80 and 0.90.

Quantitative study

The first step was the translation of the tools. To ensure cultural appropriateness and comparability across settings, a rigorous translation process was used, including forward translation into the target languages by bilingual experts and backward translation into English by independent translators. Discrepancies were resolved through consensus with the research team in each country, and items were culturally adapted where necessary to preserve conceptual equivalence while improving clarity and relevance. The next step was the recruitment of participants through online surveys via social media like Facebook, WhatsApp, X (former Twitter), Instagram and email. Social media was used as a recruitment tool to reach a broader and more diverse sample of participants across different regions. To further enhance diversity and include individuals with limited access to online platforms, additional in-person recruitment was conducted with the assistance of local psychologists. The participants used a google form link to fill out the online questionnaire. Surveys were in Swahili in Tanzania, Kinyarwanda in Rwanda, English in Uganda, and Swahili and English in Kenya. Participants were required to provide informed consent by signing either an online or paper consent form prior to completing the 30–45-minute survey.

Measures

Cultural scripts of Trauma Inventory (CSTI).

The resulting 15-item CSTI (subject to this paper) is scored on a 5-point Likert scale, ranging from 0 (never) to 4 (always). The measure is divided into five subscales: cognitive, frame of mind, body related, meaning disruption and family stress, with each subscale consisting of three items. The total score can range from 0 to 60, while subscale scores vary from 0 to 12. A score of 0 indicates no cultural related post traumatic symptoms, whereas higher scores indicate more significant cultural related post traumatic symptoms. In clinical settings, the significance of the score is linked to the severity of symptoms and corroborated with other clinical evidence.

PTSD and CPTSD.

The International Trauma Questionnaire [28] is an 18-items measure of PTSD symptoms based on criteria in the ICD-11 (WHO, 2019). The measure comprises two subscales: The first is used to assess core symptoms of PTSD (nine items), and the second relates to symptoms of CPTSD (nine items). Responses are rated on a 5-point Likert scale ranging from 0 (not at all) to 4 (extremely). The total score can range from 0 to 72, whereas subscale scores range from 0 to 36. In the present study, the reliability of the questionnaire for PTSD was excellent, Cronbach's α = .88 while for CPTSD was  .90.

Historical trauma

The 20-item of Clinical Aspects of Historical Trauma Questionnaire [29] assesses cultural patterns of man-made collective trauma prevalent in Eastern Africa. Its items are scored on a 5-point Likert scale ranging from 0 (never) to 4 (always). The measure has five subscales: distrust, exhaustion, attributed damage, cultural loss, and reproaches, with each subscale consisting of three items. Total scores can range from 0 to 80, and subscale scores range from 0 to 16. The score of 0 indicates no clinical aspects of historical trauma, whereas higher scores indicate more significant clinical aspects of historical trauma, with cut-off point of 31 score. In the present study, the reliability of the questionnaire was excellent, Cronbach's α = .90.

Purpose in life

To assess purpose of life the Existential Scale of the Purpose in Life Questionnaire (EPIL) [30] was used. It is a 7-point Likert scale ranging from 1 (the lowest level of a given response) to 7 (The highest level of the response). The high score indicates that the assessed person has a purposeful life. In the present study, the reliability of the questionnaire was excellent, Cronbach's α = .84.

General self efficacy

To assess the ability of coping with the daily life stressors and a general set of expectations that the individual carries into new situations, nine items with higher factor loadings of general self-efficacy questionnaire [31] was used. It is a 5-point Likert scale ranging from 1 (Strongly disagree) to 5 (Strongly agree). The high score indicates that the assessed person has a higher general self-efficacy. In the present study, the reliability of the questionnaire was good, Cronbach's α = .78.

Subjective vitality

To assess the culturally relevant concept of subjective vitality of the participants, a vitality questionnaire [32] was used. It is rated on a 7-point Likert scale with one item reverse scored. Higher scores indicate greater vitality. In this study, the scale showed good reliability (Cronbach’s α = .80).

Social demographics

Variables of a newly developed brief demographic questionnaire are age, gender, education, marital status, employment category, country of residency, religion and type of traumatic exposure.

Data analysis

Quantitative data [33] were analyzed using IBM SPSS and Amos (Version 29). Assumptions were checked, with no missing data, outliers, or normality issues. Descriptive statistics summarize sociodemographic characteristics. Though theory-based, an Exploratory Factor Analysis (EFA) using principal axis factoring with direct oblimin rotation was conducted. Parallel analysis and scree plot guided factor retention. Three items per factor with loadings > .50 and strong content relevance were selected. This approach follows guidelines to prioritize high-loading, meaningful items while keeping questionnaires brief [34]. Factors were validated via confirmatory factor analysis (CFA) with maximum likelihood estimation on two subsamples to check model fit and prevent overfitting. For EFA and CFA, the total sample was randomly split into two independent subsamples of 604 participants each. One subsample was used for EFA, and the second subsample was used for CFA. This split-sample (50%/50%) approach is commonly recommended in scale development when the sample size is sufficiently large, as it allows cross-validation of the factor structure while reducing the risk of overfitting. CFA was conducted only on the second subsample to confirm the factor structure identified in the EFA [35]. Internal consistency was assessed using Cronbach's alpha. Split-half reliability tested item consistency, and item analysis examined discrimination and difficulty. Construct and discriminant validity were evaluated using AVE [36] and HTMT [37]. Convergent and discriminant validity were tested using Pearson correlations. Measurement invariance was conducted to assess the questionnaire's validity and reliability across four countries. Following Byrne [38], CFA was first run in each country to ensure model fit. The model fit well in three countries, and results excluding the poorly fitting country aligned closely. Thus, measurement invariance analysis proceeded across all countries [38]

Ethical considerations

This research was approved by Ethics Committee of the University of Rwanda, College of Medicine and Health Sciences, approval nr. 396/CMHSIRB/2023, Ethics Committee of the Daystar University Kenya, approval nr. DU-ISERC/09/05/2023/00086, ETH Zurich ethics committee Nr. EK 2023-N-308, University of Dar es Salaam ethical Committee Ref. No: AB3/12(B) and Makerere University School of Health Sciences ethical committee MAKSHSREC-2026–1903. The study conforms to the principles embodied in the Declaration of Helsinki.

Inclusivity in global research

Additional information regarding the ethical, cultural, and scientific considerations specific to inclusivity in global research is included in the Supporting Information (S3 File).

Results

Qualitative results

Trauma experts’ characteristics.

The study included a total of 36 participants from Kenya (n = 10), Rwanda (n = 16), Tanzania (n = 5), and Uganda (n = 5). The sample comprised 21 females (58.3%) and 15 males (41.7%), representing a range of mental health and psychosocial professions, including clinical psychologists (n = 7), psychotherapists (n = 16), medical doctors (n = 3), social workers (n = 3), traditional healers (n = 3), and spiritual healers (n = 4). Participants’ ages ranged from 22 to 58 years (M = 40.05, SD = 9.98). Years of professional experience ranged from 1 to 20 years (M = 8.36, SD = 5.44).

Trauma survivors’ characteristics.

The sample consisted of 79 participants (age range = 21–83 years, M = 45.60, SD = 12.80) from Rwanda (n = 59), Uganda (n = 5), Kenya (n = 10), and Tanzania (n = 5). Participants included survivors of genocide (n = 20), war (n = 15), imprisonment (n = 13), ex-combatants (n = 8), accidents (n = 7), childhood trauma (n = 10), and conflict-related experiences (n = 5). Most participants were married (n = 50), followed by single (n = 18) and widowed individuals (n = 11). In terms of education, participants had primary education (n = 27), secondary education (n = 23), university-level education (n = 21), or no formal education (n = 8).

List of mapped cultural scripts of trauma suffering: Initial pool of items.

The following section presents the results that guided the item selection and formulation for the East African CSTI. The coded text segments were assigned to the following main categories: cognitions and affects, worldviews, interpersonal relationship problems, body-related symptoms, and meaning disruption and changes in family stress (see S4 File). Body-related symptoms such as headaches, back pain, dizziness, and tingling sensations were the most frequently reported, with nearly all participants. Both survivors and experts provided similar explanations for these complaints.

They described bodily symptoms as signs of silent suffering pain endured without sharing, healing, or finding ways to express distress. These accounts highlight the survivors’ need for a confidential, non-stigmatizing space in which to share their experiences.

Interpersonal relationship problems were the second largest category with twelve items. It includes difficulties with enemies (perpetrators), loss of trust in others, heightened competitiveness, and feelings of insufficient family and community support. For example, participants expressed sentiments such as: “I cannot trust anyone,” “I feel that no one wants to support me,” and “I am glad when my enemy sees my successes.” These statements illustrate the enduring impact of man-made trauma on interpersonal relationships and highlight the long-term scars it leaves on the social fabric.

The third category concerned changes in family interest and management. Participants described how traumatic experiences extend beyond the individual level to affect the entire family. Examples of such statements included: “I feel that I have an empty family,” “I am aggressive towards close others,” and “I don’t know how to manage family resources.” These accounts illustrate how trauma can deeply disrupt family functioning and contribute to a loss of hope within the family unit.

The fourth category, comprising ten items, was cognitions and affects. Although the symptoms in this category were primarily cognitive, they were often perceived in an interdependent manner. For example, participants stated: “I have no more love,” “I feel I can’t apologize” and “I feel resentment or revenge.” These expressions highlight negative cognitions directed toward others. At the same time, participants also reported personal negative cognitions, such as “I feel that I am cruel” and “I feel that I have lost my dignity.” This suggests that in collectivistic communities, negative cognitions are not only self-oriented but also relationally oriented toward others.

The fifth category concerned changes in worldview. Participants from the East African sample reported uncertainty about the future, perceptions of human unfairness, and deep disappointment with both the world and God. For example, some expressed: “I believe there is no need to plan for tomorrow” and “I doubt that there is a God.” These statements reflect how trauma disrupts an individual’s system of beliefs. In the East African context, this system is often a triple belief structure encompassing the self, the community, and God. Supporting trauma survivors therefore requires interventions that help to restore and rebuild this interconnected belief system.

Interestingly, trauma survivors also described negative experiences related to meaning and purpose in life. For example, participants stated, “I do not need to strive for myself” and “I give up easily,” reflecting a diminished sense of agency, interconnectedness, and existential meaning following traumatic experiences. All these cultural scripts of suffering are closely linked to cultural values and beliefs such as enduring sadness in silence, preserving community reputation, and maintaining Christian faith.

Quantitative results

Participant demographic characteristics.

This study included 1,208 participants from four East African countries. The mean age of the participants was 32.63 years (SD = 10.85), with a range from 18 to 81 years. Of the total sample, 34.1% (n = 412) were from Tanzania, 26.5% (n = 320) from Rwanda, 21.2% (n = 256) from Uganda, and 18.2% (n = 220) from Kenya. The sample consisted of 63.2% (n = 763) female participants, while 0.7% (n = 9) identified as a gender other than male or female. In terms of marital status, 52% (n = 628) were single, 37.3% (n = 451) were married and living with their partner, and 10.7% (n = 129) were divorced. Regarding education, 8.6% (n = 104) had completed elementary school, 19.4% (n = 234) had finished high school, 59.9% (n = 723) held a bachelor’s degree, 10.8% (n = 130) had a master’s degree, and 1.4% (n = 17) had a PhD.

Employment status revealed that 14.1% (n = 170) were unemployed, 31% (n = 375) were students, and 54.9% (n = 663) were employed. Regarding religious affiliation, 1.2% (n = 14) followed traditional religions, 2.3% (n = 28) had no religious affiliation, 16.9% (n = 204) were Muslim, and 79.6% (n = 962) were Christian. Most participants, 72.7% (n = 878), lived in urban areas.

Exploratory factor analysis of item pool.

An exploratory factor analysis (EFA) of the CSTI initially yielded a nine-factor solution with eigenvalues of 16.55, 7.83, 2.28, 2.10, 2.05, 1.66, 1.48, 1.35, and 1.17. To determine the optimal number of factors, we conducted a parallel analysis, which suggested up to eight factors exceeding randomly generated eigenvalues (1.50, 1.47, 1.44, 1.41, 1.39, 1.37, 1.35, 1.33, 1.32, 1.32). However, inspection of the scree plot (Fig 1), together with the parallel analysis scree line, indicated a clear break after the fifth factor, suggesting a more parsimonious five-factor solution.

Fig 1. Scatter plot of parallel analysis.

Fig 1

In addition, the last three factors of the higher-order solutions explained less than 1% of variance each and showed unstable item patterns with substantial cross-loadings and conceptual overlap. Simulation results further indicated that eigenvalues beyond the fifth factor closely approximated those expected under random data, supporting retention of five factors.

Based on these converging criteria, a final EFA was conducted specifying a five-factor solution, which demonstrated a stable and interpretable structure consistent with the theoretical framework of the Cultural Script of Trauma (CST). This final five-factor solution was subsequently used for CFA and item selection. For the CFA, the three highest-loading and most conceptually representative items per factor were retained, resulting in a final 15-item CSTI (Table 1).

Table 1. Final 15-items Cultural Script of Trauma Inventory in all languages (CSTI) (S5 File).
No English Score
0 1 2 3 4
Cognitive
1 I have no more love
2 I no longer feel like a person like others
3 I feel that I have lost my dignity
Frame of mind
4 I believe that there is no need to plan for tomorrow
5 I feel that no one wants to support me
6 I feel like I do not have a role model in my life
Body related
7 I have sleeping problems
8 I have headaches
9 I feel tingling in my skin
Meaning disruption
10 I do not need to strive for myself
11 Since that time, I have not achieved any success.
12 I do not have faith that everything is possible.
Family stress
13 I feel that I have an empty family
14 I am aggressive towards close others
15 I don't know how to manage family resources

Instructions: The following statements describe problems that people sometimes report in response to traumatic or stressful life events. Please read each statement carefully, then circle one of the numbers to the right to indicate how much you have been bothered by that problem in the past month. Write down one event that affected you more deeply than any other, and use it as a reference point when answering the questions: e.g., genocide, childhood trauma, war, accident, imprisonment etc.

Notes: Items 2, 4, 8, 10, 14 were found to be consistent in all countries as shown by partial scalar invariance.

Item Scoring: 0: Strongly Disagree; 1: Disagree; 2: Neutral; 3: Agree; 4: Strongly agree

Total Scale Scoring: The CSTI ranges from 0 to 60, with 0 indicating absence of CST symptoms. A score ≥2 on any subscale, especially when accompanied by clinical symptoms or functional impairment, is considered clinically significant. In clinical settings, even one CST symptom scored ≥2 may warrant clinical attention.

Confirmatory factor analysis.

Table 2 presents the CSTI model fit indices. Model fit was considered adequate if it met the following criteria: χ²/df ≤ 3.0, RMSEA ≤ .08, SRMR ≤ .10, CFI, TLI, and GFI ≥ .95 (Kline, 2011). The five-factor model showed good fit for each factor and the overall structure. As expected, the single-factor model fit poorly, with all indices below cutoff values. Results were consistent across countries, except Kenya. However, CFA excluding Kenya produced similar outcomes, and reliability and construct validity remained strong, supporting the questionnaire's use in Kenya (see Table 2).

Table 2. CFA fit indices.
Fit index Four-country model (5-factor) One-factor model (4 countries) Rwanda (5-factor) Uganda (5-factor) Tanzania (5-factor) Kenya (5-factor) Three-country model, excluding Kenya (5-factor)
χ²/df 2.18 15.10 1.35 1.56 1.62 1.58 2.18
CFI 0.98 0.77 0.99 0.97 0.94 0.96 0.97
TLI 0.97 0.73 0.98 0.96 0.93 0.95 0.97
GFI 0.98 0.91 0.98 0.96 0.96 0.99 0.98
RMSEA 0.035 0.10 0.024 0.042 0.050 0.039 0.035
SRMR 0.032 0.070 0.032 0.050 0.045 0.046 0.032

Note. The four-country model represents the proposed five-factor structure tested across Rwanda, Uganda, Tanzania, and Kenya. The one-factor model represents a single-factor alternative tested across all four countries. Country-specific models use the five-factor structure. The three-country model excludes Kenya.

Tests of reliability.

Table 3 shows the internal consistency of the final CSTI and its subscales. The total scale demonstrated strong reliability (Cronbach’s α = .85). Subscales showed adequate consistency: Cognitive (α = .76), Frame of Mind (α = .68), Body-Related Symptoms (α = .74), Difficulties in Meaning Disruption (α = .72), and Family Stress (α = .67). Split-half reliability was good, and item analysis indicated strong discrimination and difficulty indices. High factor loadings further confirmed item reliability (see Table 4).

Table 3. Item analysis and reliability.
Items DI Item α value ID (Mean) Items factor loadings
Item 1 0.57 0.85 1.6 0.80
Item 2 0.607 0.84 1.42 0.86
Item 3 0.625 0.84 1.43 0.91
Item 4 0.413 0.85 1.52 0.76
Item 5 0.506 0.85 1.62 0.71
Item 6 0.365 0.86 1.82 0.58
Item 7 0.511 0.85 1.74 0.86
Item 8 0.566 0.85 1.6 0.98
Item 9 0.565 0.85 1.45 0.74
Item 10 0.233 0.86 1.35 0.61
Item 11 0.422 0.85 1.24 0.85
Item 12 0.416 0.85 1.18 0.76
Item 13 0.548 0.85 1.52 0.76
Item 14 0.568 0.85 1.46 0.75
Item 15 0.509 0.85 1.47 0.61
General reliability 0.85

DI: discrimination Index, ID: Index of difficulty.

Table 4. Descriminant validity.
Cognitive Frame of mind Body related Meaning disruption Family stress
Cognitive
World view 0.835
Body related 0.725 0.763
Meaning Disruption 0.285 0.309 0.177
Family stress 0.707 0.866 0.701 0.218

This number represents Heterotrait-monotrait ratio (HTMT) values.

Tests of validity.

Table 4 presents the HTMT ratios, confirming discriminant validity for all subscales with values below  .85. Table 5 shows construct validity results, with each subscale demonstrating AVE > .40 and composite reliability > .60 (Fornell & Larcker, 1981).

Table 5. Construct validity.
Construct
Cognitive and affects 0.5
Frame of mind 0.4
Body related 0.5
Meaning disruption 0.4
Family stress 0.4

This number represent Average variance extracted (AVE) to each dimension

Table 6 displays correlations between CSTI and other measures. CSTI was positively correlated with PTSD, CPTSD, and CAHTQ (convergent validity), and negatively correlated with purpose in life, self-efficacy, and subjective vitality (discriminant validity).

Table 6. Convergent and divergent validity.
CSTI CAHTQ PTSD DSO Purpose in Life General Self Efficacy Subjective vitality
CSTI
CAHTQ .503**
PTSD .511** .658**
DSO .465** .494** .551**
Purpose in Life −.509** −.366** −.441** −.373**
General Self Efficacy −.517** −.418** −.465** −.401** .482**
Subjective vitality −.497** −.278** −.385** −.411** .603** .559**
Personal Mastery −.233** −.252** −.261** −.347** .219** .360** .242**

** Correlation is significant at the 0.01 level (2-tailed).

Note: CSTI: Cultural Script of Trauma Inventory, CAHTQ: Clinical Aspects of Historical Trauma Questionnaire, PTSD: Post Traumatic Stress Disorders, DSO: Disturbances in Self Organization.

Measurement of invariance

Table 7 shows that four types of invariances were tested across four East African countries, confirming the CSTI’s reliability and validity. Adequate model fit was based on ΔCFI ≤ 0.01, ΔMc NCI ≤ 0.01, and Δγ ≤ 0.2 [39]. Configural and metric invariance were fully supported, partial scalar invariance was achieved with five items, but residual invariance did not hold (Table 7).

Table 7. Measurement of invariance.

Model Model description χ² df CFI gamma hat Mc NCI Δχ² Δdf sig. ΔCFI ΔMc NCI Δgamma hat
1 Configural invariance 535.12 320.00 0.95 0.98 0.91
2 Metric 634.34 350.00 0.94 0.97 0.89 99.22 30.00 >.001 0.01 0.02 0.01
3 Partial scalar 735.93 360.00 0.93 0.96 0.85 101.58 10.00 >.001 0.01 0.03 0.01
4 Partial residuals invariance 1029.15 405.00 0.88 0.93 0.77 293.22 45.00 >.001 0.05 0.08 0.03

Notes: χ²: Chi Square, df: Degrees of Freedom, Comparative fit index (CFI) Δ: Difference, Mc NCI: McDonald’s non-centrality index, Significance of P value.

Discussion

This study aims to map culturally scripts of trauma sufferings and to develop and validate the Cultural Scripts of Trauma Inventory (CSTI) across Eastern African countries, including Rwanda, Uganda, Tanzania, and Kenya to enable culturally informed diagnostics beyond PTSD and CPTSD (see S6 File). The qualitative study identified 71 items, which were organized into six categories: cognitions and affects, interpersonal relationship problems, changes in worldview, body-related symptoms, meaning disruption, and changes in family interest and management. In contrast to the Swiss sample, which revealed cultural scripts of trauma largely overlapping with CPTSD symptoms [17], the East African sample demonstrated symptoms that were more culturally specific. This highlights why trauma survivors in developing countries often do not fully fit the conventional PTSD criteria.

Cognitive and affective symptoms were often relationally oriented, highlighting how negative thoughts and emotions in collectivistic communities affected by man-made trauma extend beyond the self to others. Therefore, interventions should address both personal and relational dimensions. Changes in worldview reflected disruptions in the triple belief system encompassing the self, community, and God. This has important implications for diagnosis and treatment, as effective interventions should aim to restore and rebuild this interconnected belief system.

Nearly all trauma survivors reported body-related symptoms, indicating silence embedded suffering that many describe as unspeakable which require the safe and non-stigmatizing spaces [11]. This need is particularly important in this community, and their voices should be acknowledged and prioritized. Notably, survivors also reported problems in meaning and purpose in life, in the statement like I do not need to stive for my life, and my future is not needed. Such statements demonstrate lack of resilience and determination, and they may also suggest a diminished sense of interconnectedness and meaning in life. The qualitative findings also indicated that trauma extends beyond the individual to affect family and community levels, suggesting that interventions should adopt a multisystemic approach [14]. Although PTSD criteria mainly focus on individual symptoms, the effects of trauma appear to extend beyond the individual level in many communities.

In this study, symptoms such as family stress and aggressiveness illustrate how trauma in East African settings can deeply disrupt family functioning and contribute to a loss of hope within the family unit—manifestations that are not reflected in the DSM and ICD. Nevertheless, these results corroborate with research in Western sample which has shown that trauma can affect parenting practices, partner and interpersonal relationships, and children’s well-being [40,41]. The only simple difference is that such effects in Western contexts are often limited to nuclear family. However, in the East African context, forms of family disruption such as experiences of an “empty family and mistrust” may extend beyond the nuclear family to encompass the broader kinship network and community systems, reflecting the more relational and interconnected nature of family structure.

While qualitative studies found six categories the CFA only confirm five categories: cognitive and affects, body-related, meaning disruption, family stress and frame of mind. “Frame of mind” was chosen as a label for three items grouped together after EFA because they reflect a common mindset in the region marked by a lack of future planning due to ongoing uncertainties and doubts about reliable support. This mindset stems from repeated trauma, which undermines confidence in stability and social networks, highlighting the need to help East African trauma survivors rebuild purpose and restore social connections. The interpersonal category was not identified as a distinct factor, likely because family-related stress was more prevalent, causing item overlap. Similarly, items related to changes in worldview did not emerge as a separate factor, as many of these items were captured under the broader “frame of mind” dimension. This may reflect the tendency of trauma survivors to focus on fears and uncertainties about the future.

The factors with the highest loadings were body-related and cognitive symptoms, emphasizing their importance in post-traumatic stress treatment in East Africa. CFA and measurement invariance showed excellent fit across four countries, supporting the tool’s reliability. Although the CFA fit for Kenya was somewhat less satisfactory, however, the Comparative Fit Index (CFI) was relatively acceptable, and other psychometric properties, including factor loadings, internal consistency, and overall factor structure, were satisfactory. This suggests that the scale retains acceptable structural validity in this context, but further studies should explore the reason for such heterogeneity.

It is important to note that the symptoms of lack of future planning, bitterness, headaches, lack of agency, and aggressiveness towards close relationships emerged as significant concerns across all countries studied, as indicated by the findings of partial scalar invariance. These symptoms highlight the pervasive impact of trauma on individuals’ mental health and interpersonal dynamics. Understanding these central symptoms and signs is crucial for developing effective, culturally sensitive interventions that can help individuals in these contexts regain agency, purpose in life, vitality, rebuild their social connections and resilience [42,43].

The inventory shows strong internal consistency and reliable items. Each factor demonstrates adequate reliability, allowing use as standalone measures. Construct and discriminant validity are confirmed, along with convergent and divergent validity, indicating the CSTI is an effective tool for assessing culturally relevant post-traumatic symptoms in this sample. Few elements of CST categories of cognitive and affective changes and interpersonal relationships not included in the inventory may overlap with core DSM symptom clusters for trauma-related disorders, although their expression differs. For example, hyperarousal may be reflected in experiences of nervousness and hypersensitivity, while negative alterations in cognition and mood are expressed as sadness. However, several CST features in same categories, such as revengeful thoughts and loss of pride, are not captured within standard DSM symptom categories. At the same time, several CST categories extend beyond DSM symptom organization, particularly frame of mind changes, meaning disruption, family-level stress, and body related symptoms. These domains reflect broader socio-cultural and existential dimensions of trauma that are not fully captured by DSM and ICD categories, which are primarily focused on individual psychopathology.

Overall, these findings support a dual perspective on trauma symptoms. First, some symptoms appear relatively universal across cultures, while their expression, salience, and meanings are culturally shaped and embedded within broader social, familial, and moral systems. Second, certain symptoms may be culturally specific and occur only within cultural contexts.

This study has several limitations. First, its retrospective design may introduce memory bias. As a self-report tool, the questionnaire may overlook some important symptoms. Although several countries were involved in its development, validation was limited to four. Further validation in other countries is needed. While the inventory identifies CST in East Africa, future research should examine the sequence and network of symptoms, as well as the diversity of symptom patterns across subcultural groups. Many participants are relatively young, particularly in the quantitative component, which may limit age diversity. However, this reflects regional demographics, where approximately 85–91% of the population is below 45 years. To further mitigate this limitation, the qualitative sample is more age diverse. Recruitment varied across countries using both online and in-person methods, which may introduce some inconsistency, but also enabled broader reach across different contexts. Although some participants were students based in urban areas due to the location of universities, most maintain strong rural ties or lived rural experience, reducing potential urban bias and supporting contextual relevance. Furthermore, the ≥ 2 threshold mentioned was used as a pragmatic indicator of symptom presence rather than a diagnostic cutoff. Clinically meaningful cutoffs require validation in clinical samples using sensitivity and specificity analyses and remain a direction for future research.

Conclusions and implications

Culture plays a crucial role in the treatment of patients experiencing post-traumatic symptoms. While PTSD and CPTSD are the most recognized diagnostic categories globally, with established and validated measurement tools, there is a pressing need to consider culturally specific experiences in the assessment and treatment of trauma. This study introduces further culturally specific post traumatic sufferings and a new measurement for assessing culturally relevant post-traumatic experiences in three languages, which encourages clinicians and researchers to move beyond a purely universal model of mental health diagnosis and treatment. The 15-item CSTI should be used in addition to the existing 18-item ITQ for ICD-11 PTSD and CPTSD. Future validation of this measurement in other African countries and corresponding studies in other cultural regions in the world is vital for broadening its clinical use.

Supporting information

S1 File. Interview Guide.

(XLSX)

pone.0358482.s001.xlsx (9.4KB, xlsx)
S2 File. CST code book final.

(XLSX)

pone.0358482.s002.xlsx (16.8KB, xlsx)
S3 File. Inclusivity in global research.

(DOCX)

pone.0358482.s003.docx (68.1KB, docx)
S4 File. List of mapped cultural scripts of trauma suffering: initial pool of items.

(DOCX)

pone.0358482.s004.docx (25.4KB, docx)
S5 File. Cultural Script of Trauma Inventory (CSTI).

(DOCX)

pone.0358482.s005.docx (18.4KB, docx)
S6 File. Complete description of qualitative dataset.

(DOCX)

pone.0358482.s006.docx (17.8KB, docx)

Acknowledgments

The author would like to express gratitude to collaborators in ethical submission, recruitment of participants, translation of materials and data entry and quality control in the online systems from various universities. Those collaborators include Prof. Vincent Sezibera, Joseph Kalisa, Nicole Iraguha, Jonas Bikorimana, Samuel Murwanashyaka, and Adelite Mukamana from the University of Rwanda. Thanks, are also extended to Nshakira Keren and James Bagume from Makerere University in Uganda, Prof. Stephen Asatsa and Shantal Anyango from the Catholic University of Eastern Africa, as well as Dr. George Mutelmwa from the University of Saint Augustine in Tanzania. Additional appreciation goes to Dr. George Mabula or University of Dar es Salaam (DUCE).

Data Availability

Quantitative data are available in the public repository: https://doi.org/10.5281/zenodo.20385027. Qualitative date restrictions details: data contain potentially identifying and sensitive trauma survivors information The restrictions is imposed by College of Medicine and Health Sceinces Ethical Committee (researchcenter@ur.ac.rw) Daystar Univesity Institutional Scientific and Ethics Review Committee (info@daystar.ace.ke), and University of Dar es Salaam Ethical Committee (vc@admin.udsm.ac.tz).

Funding Statement

Foundation of the Works of C.G. Jung Award Number: N/A | Recipient: Andreas of Maercker The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

References

  • 1.Benjet C, Bromet E, Karam EG, Kessler RC, McLaughlin KA, Ruscio AM, et al. The epidemiology of traumatic event exposure worldwide: results from the World Mental Health Survey Consortium. Psychol Med. 2016;46(2):327–43. doi: 10.1017/S0033291715001981 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Koenen KC, Ratanatharathorn A, Ng L, McLaughlin KA, Bromet EJ, Stein DJ. Posttraumatic stress disorder in the World Mental Health Surveys. Psychol Med. 2017;47(13):2260–74. doi: 10.1017/S0033291717000708 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Musisi S, Kinyanda E. Long-term impact of war, civil war, and persecution in civilian populations-conflict and post-traumatic stress in African communities. Front Psychiatry. 2020;11:20. doi: 10.3389/fpsyt.2020.00020 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Mutuyimana C, Cassady C, Sezibera V, Nsabimana E. Prevalence and correlates of depression among rural and urban Rwandan mothers and their daughters 26 years after the 1994 genocide against the Tutsi. Eur J Psychotraumatol. 2021;12(1):2005345. doi: 10.1080/20008198.2021.2005345 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Bovey M, Hosny N, Dutray F, Heim E. PTSD and complex PTSD manifestations in Sub-Saharan Africa: A systematic review of qualitative literature. SSM - Ment Health. 2024;5:100298. doi: 10.1016/j.ssmmh.2024.100298 [DOI] [Google Scholar]
  • 6.Mutuyimana C, Thoma MV, Maercker A, Sezibera V, Heim E. Caseness and comorbidity of probable (complex) post-traumatic stress disorder and depression in survivors of genocide against Tutsi in Rwanda: the role of social determinants. South Afr J Psychol. 2023. doi: 10.1177/00812463231186269 [DOI] [Google Scholar]
  • 7.Nicholas A, Joshua O, Elizabeth O. Accessing Mental Health Services in Africa: Current state, efforts, challenges and recommendation. Ann Med Surg (Lond). 2022;81:104421. doi: 10.1016/j.amsu.2022.104421 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Sankoh O, Sevalie S, Weston M. Mental health in Africa. Lancet Glob Health. 2018;6(9):e954–5. doi: 10.1016/S2214-109X(18)30303-6 [DOI] [PubMed] [Google Scholar]
  • 9.Mutuyimana C, Maercker A. Elements of cultural scripts of trauma sequelae among trauma victims in East Africa. Front Psychol. 2023;14:1206503. doi: 10.3389/fpsyg.2023.1206503 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Maercker A, Bachem R, Mutuyimana C, Eberle D. Toward cultural scripts of trauma sequelae. Psychother Psychosom Med Psychol. 2024;74(7):276–85. doi: 10.1055/a-2276-4992 [DOI] [PubMed] [Google Scholar]
  • 11.Mutuyimana C, Maercker A. Elements of cultural scripts of trauma sequelae among trauma victims in East Africa. Front Psychol. 2023;14. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 12.Claudius M, Shino EN, Job S, Hofmann D, Thalmayer AG. Still Standing Inside: A Local Idiom Related to Trauma among Namibian Speakers of Khoekhoegowab. Int J Environ Res Public Health. 2022;19(21):14323. doi: 10.3390/ijerph192114323 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Mutuyimana C. Historical trauma and cultural scripts of trauma among trauma survivors in Rwanda and East Africa. University of Zurich. 2023. https://www.zora.uzh.ch/handle/20.500.14742/208500 [Google Scholar]
  • 14.Maercker A, Mutuyimana C. Rethinking trauma diagnoses as a global challenge. Title of the book not provided. 2026. p. 13–25. doi: 10.1007/978-3-032-21028-9_2 [DOI] [Google Scholar]
  • 15.Wen Y, Maercker A, Adank N, Mutuyimana C. Cultural Scripts of Trauma in East Africa Predicted by Cultural and Intrapersonal Factors: Path Analysis of a New Psychopathological Concept. Clin Psychol Psychother. 2026;33(1):e70225. doi: 10.1002/cpp.70225 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 16.Chentsova-Dutton Y, Maercker A. Cultural scripts of traumatic stress: Outline, illustrations, and research opportunities. Frontiers in Psychology. 2019;10. doi: 10.3389/fpsyg.2019.02528 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Bachem R, Mazza A, Eberle DJ, Maercker A. A new approach to cultural scripts of trauma sequelae assessment: The sample case of Switzerland. PLoS One. 2024;19(4):e0301645. doi: 10.1371/journal.pone.0301645 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.Nichter M. Idioms of Distress. 2018. doi: 10.1002/9781118924396.wbiea2018 [DOI] [Google Scholar]
  • 19.Kidron CA, Kirmayer LJ. Global mental health and idioms of distress: the paradox of culture-sensitive pathologization of distress in Cambodia. Cult Med Psychiatry. 2019;43(2):211–35. doi: 10.1007/s11013-018-9612-9 [DOI] [PubMed] [Google Scholar]
  • 20.Kaiser BN, Jo Weaver L. Culture-bound syndromes, idioms of distress, and cultural concepts of distress: New directions for an old concept in psychological anthropology. Transcult Psychiatry. 2019;56(4):589–98. doi: 10.1177/1363461519862708 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Heim E, Karatzias T, Maercker A. Cultural concepts of distress and complex PTSD: Future directions for research and treatment. Clin Psychol Rev. 2022;93:102143. doi: 10.1016/j.cpr.2022.102143 [DOI] [PubMed] [Google Scholar]
  • 22.Kohrt BA, Rasmussen A, Kaiser BN, Haroz EE, Maharjan SM, Mutamba BB, et al. Cultural concepts of distress and psychiatric disorders: literature review and research recommendations for global mental health epidemiology. Int J Epidemiol. 2014;43(2):365–406. doi: 10.1093/ije/dyt227 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Martínez-Radl FB, Hinton DE, Stangier U. Susto as a cultural conceptualization of distress: Existing research and aspects to consider for future investigations. Transcult Psychiatry. 2023;60(4):690–702. doi: 10.1177/13634615231163986 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24.Thalmayer AG, Toscanelli C, Arnett JJ. The neglected 95% revisited: Is American psychology becoming less American? Am Psychol. 2021;76(1):116–29. doi: 10.1037/amp0000622 [DOI] [PubMed] [Google Scholar]
  • 25.Dückers MLA, Alisic E, Brewin CR. A vulnerability paradox in the cross-national prevalence of post-traumatic stress disorder. Br J Psychiatry. 2016;209(4):300–5. doi: 10.1192/bjp.bp.115.176628 [DOI] [PubMed] [Google Scholar]
  • 26.Jobson L, Qiu LS, Wong J, Li H, Lies J, Lau W, et al. Cultural differences in appraisals of control and posttraumatic stress disorder symptoms. Eur J Psychotraumatol. 2024;15(1):2358685. doi: 10.1080/20008066.2024.2358685 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 27.Braun V, Clarke V. Using thematic analysis in psychology. Qual Res Psychol. 2006;3(2):77–101. doi: 10.1191/1478088706qp063oa [DOI] [Google Scholar]
  • 28.Cloitre M, Shevlin M, Brewin CR, Bisson JI, Roberts NP, Maercker A, et al. The International Trauma Questionnaire: development of a self-report measure of ICD-11 PTSD and complex PTSD. Acta Psychiatr Scand. 2018;138(6):536–46. doi: 10.1111/acps.12956 [DOI] [PubMed] [Google Scholar]
  • 29.Mutuyimana C, Maercker A. Development and validation of the Clinical Aspects of Historical Trauma Questionnaire in Rwandan genocide survivors. J Trauma Stress. 2022;35(4):1189–200. doi: 10.1002/jts.22829 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 30.Law BMF. Psychometric properties of the existence subscale of the purpose in life questionnaire for Chinese adolescents in Hong Kong. ScientificWorldJournal. 2012;2012:685741. doi: 10.1100/2012/685741 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 31.Sherer M, Maddux JE, Mercandante B, Prentice-Dunn S, Jacobs B, Rogers RW. The Self-Efficacy Scale: Construction and Validation. Psychol Rep. 1982;51(2):663–71. doi: 10.2466/pr0.1982.51.2.663 [DOI] [Google Scholar]
  • 32.Bostic TJ, Rubio DM, Hood M. A validation of the subjective vitality scale using structural equation modeling. Soc Indic Res. 2000;52(3):313–24. [Google Scholar]
  • 33.Mutuyimana C. Cross validation of cultural scripts of trauma inventory, clinical aspects of historical trauma questionnaire and assessment of protective factors of long-term effects of trauma in eastern african population. 2016. https://zenodo.org/records/20385027 Accessed 2026 June 1. [Google Scholar]
  • 34.DeVellis RF. Scale Development: Theory and Applications. Fourth ed. Los Angeles: SAGE Publications, Inc. 2016. [Google Scholar]
  • 35.Worthington RL, Whittaker TA. Scale development research: A content analysis and recommendations for best practices. Couns Psychol. 2006;34(6):806–38. doi: 10.1177/0011000006288127 [DOI] [Google Scholar]
  • 36.Fornell C, Larcker DF. Evaluating structural equation models with unobservable variables and measurement error. J Mark Res. 1981;18(1):39–50. doi: 10.2307/3151312 [DOI] [Google Scholar]
  • 37.Henseler J, Ringle CM, Sarstedt M. A new criterion for assessing discriminant validity in variance-based structural equation modeling. J Acad Mark Sci. 2015;43(1):115–35. doi: 10.1007/s11747-014-0403-8 [DOI] [Google Scholar]
  • 38.Byrne BM. Structural equation modeling with AMOS: Basic concepts, applications, and programming. 2nd ed. New York, NY, US: Routledge/Taylor & Francis Group. 2010. [Google Scholar]
  • 39.Cheung GW, Rensvold RB. Evaluating Goodness-of-Fit Indexes for Testing Measurement Invariance. Structural Equation Modeling: A Multidisciplinary Journal. 2002;9(2):233–55. doi: 10.1207/S15328007SEM0902_5 [DOI] [Google Scholar]
  • 40.Christie H, Hamilton-Giachritsis C, McGuire R, Bisson JI, Roberts NP, Underwood JFG, et al. Exploring the Perceived Impact of Parental PTSD on Parents and Parenting Behaviours—A Qualitative Study. J Child Fam Stud. 2023;32(11):3378–88. doi: 10.1007/s10826-023-02614-z [DOI] [Google Scholar]
  • 41.Ray SL, Vanstone M. The impact of PTSD on veterans’ family relationships: an interpretative phenomenological inquiry. Int J Nurs Stud. 2009;46(6):838–47. doi: 10.1016/j.ijnurstu.2009.01.002 [DOI] [PubMed] [Google Scholar]
  • 42.Mutuyimana C, Maercker A. How meaning in life and vitality are associated with posttrauma outcomes: A systematic review. J Trauma Stress. 2024. doi: 10.1002/jts.23040 [DOI] [PubMed] [Google Scholar]
  • 43.Mutuyimana C, Wen J. Intergenerational associations of resilience and traumatic exposure with post-traumatic stress disorder (PTSD) symptoms. Int J Mental Health. 2025;1–13. doi: 10.1080/00207411.2025.2526219 [DOI] [Google Scholar]

Decision Letter 0

Inga Schalinski

24 Mar 2026

Dear Dr. Mutuyimana,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by May 08 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

  • A letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols.

As the corresponding author, your ORCID iD is verified in the submission system and will appear in the published article. PLOS supports the use of ORCID, and we encourage all coauthors to register for an ORCID iD and use it as well. Please encourage your coauthors to verify their ORCID iD within the submission system before final acceptance, as unverified ORCID iDs will not appear in the published article. Only  the individual author can complete the verification step; PLOS staff cannot  verify ORCID iDs on behalf of authors.

We look forward to receiving your revised manuscript.

Kind regards,

Inga Schalinski

Academic Editor

PLOS One

Journal Requirements:

When submitting your revision, we need you to address these additional requirements.

1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at

https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and

https://journals.plos.org/plosone/s/file?id=ba62/PLOSOne_formatting_sample_title_authors_affiliations.pdf

2. Please include a complete copy of PLOS’ questionnaire on inclusivity in global research in your revised manuscript. Our policy for research in this area aims to improve transparency in the reporting of research performed outside of researchers’ own country or community. The policy applies to researchers who have travelled to a different country to conduct research, research with Indigenous populations or their lands, and research on cultural artefacts. The questionnaire can also be requested at the journal’s discretion for any other submissions, even if these conditions are not met.  Please find more information on the policy and a link to download a blank copy of the questionnaire here: https://journals.plos.org/plosone/s/best-practices-in-research-reporting. Please upload a completed version of your questionnaire as Supporting Information when you resubmit your manuscript.

3. We note that the grant information you provided in the ‘Funding Information’ and ‘Financial Disclosure’ sections do not match.

When you resubmit, please ensure that you provide the correct grant numbers for the awards you received for your study in the ‘Funding Information’ section.

4. We note that you have indicated that there are restrictions to data sharing for this study. For studies involving human research participant data or other sensitive data, we encourage authors to share de-identified or anonymized data. However, when data cannot be publicly shared for ethical reasons, we allow authors to make their data sets available upon request. For information on unacceptable data access restrictions, please see http://journals.plos.org/plosone/s/data-availability#loc-unacceptable-data-access-restrictions.

Before we proceed with your manuscript, please address the following prompts:

a) If there are ethical or legal restrictions on sharing a de-identified data set, please explain them in detail (e.g., data contain potentially identifying or sensitive patient information, data are owned by a third-party organization, etc.) and who has imposed them (e.g., a Research Ethics Committee or Institutional Review Board, etc.). Please also provide contact information for a data access committee, ethics committee, or other institutional body to which data requests may be sent.

b) If there are no restrictions, please upload the minimal anonymized data set necessary to replicate your study findings to a stable, public repository and provide us with the relevant URLs, DOIs, or accession numbers. Please see http://www.bmj.com/content/340/bmj.c181.long for guidelines on how to de-identify and prepare clinical data for publication. For a list of recommended repositories, please see https://journals.plos.org/plosone/s/recommended-repositories. You also have the option of uploading the data as Supporting Information files, but we would recommend depositing data directly to a data repository if possible.

Please update your Data Availability statement in the submission form accordingly.

5. If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

**********

2. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: I Don't Know

Reviewer #2: Yes

Reviewer #3: Yes

**********

3. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

Reviewer #2: No

Reviewer #3: Yes

**********

Reviewer #1: I am not a statistics expert, so I can't confirm the accuracy of the statistics performed in this manuscript. I believe the authors are not allowed to share the data from this study, but it would be helpful to have more qualitative data incorporated into the manuscript if possible.

The English in the manuscript is acceptable, but some editing is required.

Reviewer #2: Peer Review Report

Manuscript PONE-D-25-53823 - Eastern African Expressions of Suffering: a new Cultural Scripts of Trauma Inventory

Overall Evaluation

This manuscript presents the development and validation of the Cultural Scripts of Trauma Inventory (CSTI), a new measure intended to capture culturally specific trauma-related expressions in East African populations (Rwanda, Uganda, Tanzania, Kenya). The study uses a mixed-methods design, beginning with qualitative focus groups to generate culturally grounded items, followed by a large quantitative validation study (N = 1,208). The research addresses an important gap in trauma research by attempting to move beyond Western-centric PTSD frameworks and incorporating culturally contextualized symptoms.

Overall, the manuscript tackles an important and timely topic, and the large multi-country sample and mixed-method approach are clear strengths. Additionally, incorporating the voices of individuals with lived experiences, as well as traditional and spiritual healers, is another strength. However, several methodological, conceptual, and reporting issues limit the clarity and robustness of the conclusions. In its current form, the manuscript would benefit from revision.

I see several strengths of this manuscript:

The study addresses a significant limitation in global trauma research: the dominance of Western PTSD frameworks and the underrepresentation of culturally specific expressions of distress. Developing a culturally sensitive measure is highly relevant for global mental health. Therefore, this manuscript may provide an important conceptual contribution to the research field.

The qualitative → quantitative sequential design is appropriate for a scale development. Using focus groups to generate culturally grounded items strengthens ecological validity.

The quantitative validation sample is relatively large (N = 1,208 across four countries), which increases statistical power and supports factor analytic procedures.

Including multiple East African countries improves generalizability compared to single-country scale development and supports a cross—cultural approach.

The authors attempt to apply standard psychometric procedures, including exploratory factor analysis, confirmatory factor analysis, measurement invariance, reliability analyses, convergent/divergent validity. These are appropriate methods for instrument validation.

However, several major concerns remain, including the following:

Conceptual clarity of “Cultural Scripts of Trauma”:

The concept of Cultural Scripts of Trauma (CST) is central to the paper but remains insufficiently defined and theoretically grounded. While the concept is briefly introduced, it is not clearly differentiated from related constructs such as idioms of distress or cultural syndromes, which leaves the concept somewhat vague. The introduction would benefit from clarifying how CST differs from idioms of distress and how it relates to the DSM-5 framework of cultural concepts of distress. The introduction should include some basic literature on cultural idioms of distress, the cultural adaptations in DSM-5 and ICD-11, transcultural psychiatry and global mental health.

The manuscript could also benefit from engaging more explicitly with the cultural considerations reflected in the ICD-11 framework for PTSD and Complex PTSD. Evidence supporting ICD-11 highlights the cross-cultural validity of CPTSD in both Western and non-Western contexts, identifies low self-compassion as a consistent marker across cultures, and acknowledges that while PTSD is globally recognized, the expression of symptoms may vary across cultural settings. In this context, CST—and particularly the CSTI—could be positioned as a useful tool for capturing such culturally shaped differences in symptom expression.

Sampling bias in the quantitative study:

Participants were recruited via social media platforms (Facebook, WhatsApp, Instagram, X). This creates some bias: high education level (≈60% bachelor’s degree), urban skew (≈73% urban) and likely younger, digitally connected populations. This contradicts the claim that the measure reflects broader East African cultural expressions. The authors should acknowledge the selection bias and the limited representation of rural or less educated populations in the limitation section. This is particularly important because trauma experiences may be often more prevalent in non-urban populations.

Item development process unclear:

The development of the 15-item CSTI is not completely clear to me. How were the initial 98 items generated? Were items derived directly from qualitative data? Were coders independent? The authors could provide a clearer development workflow, e.g. qualitative coding, item generation, expert review, pilot testing and item reduction criteria. The decision rules in reduction from 98 to 71 to 15 items could also be better described. Reducing 71 culturally rich items to only 15 items may also remove meaningful cultural nuance and may even oversimplify the construct. Moreover, only three items per factor are few and might be statistically fragile. The authors could justify on these issues.

Factor analytic procedure is not fully appropriate:

The manuscript uses EFA and CFA on the same dataset. Although the authors mention two subsamples, it is unclear how the split was conducted and whether the EFA and CFA samples were independent. This could introduce overfitting. The authors should clarify the exact subsample sizes and whether EFA and CFA were conducted on separate datasets. Moreover, the CFA results show poor model fit for Kenya. However, the manuscript dismisses this issue too quickly and still recommends the scale for Kenya. The authors should investigate why Kenya differs, test measurement invariance more thoroughly and consider cultural heterogeneity.

Interpretation sometimes exceeds the evidence:

Several claims in the discussion are stronger than the results support. For example,

the paper claims the CSTI enables “culturally informed diagnosis and treatment.” However, the study did not test clinical outcomes and the sample was not clinical. The authors might tone down these claims.

The manuscript suggests that one item score ≥2 may be clinically significant. This is not empirically justified. Diagnostic thresholds might need a clinical validation.

Minor Concerns

The manuscript contains many grammatical errors. These appear throughout the manuscript. The paper requires professional language editing.

Examples:

• “culturally scripts of trauma sufferings”

• “the confirmatory factor analysis confirm”

• “sequalae”

• “Survivors in Namibia was perceiving their sufferance as something standing inside“-> e.g.: “Survivors in Namibia perceived their suffering as something that existed within them.“

• “exeperts“

• e.g. lines 5, 6, 23: Spaces are missing or duplicated.

Some sentences sound awkward in academic English:

• Line 11: “Those sufferings are in a new theory investigated as Cultural 12 Scripts of Trauma (CST)“ -> e.g.: “These forms of suffering are conceptualized in a new theoretical framework as Cultural Scripts of Trauma (CST).“

• Line 91: “The 20-item of Clinical Aspects of Historical Trauma Questionnaire concerns cultural patterns of men-made collective trauma, prevalent in Eastern Africa.“ -> e.g. “The 20-item Clinical Aspects of Historical Trauma Questionnaire assesses cultural patterns of man-made collective trauma prevalent in Eastern Africa.“

Methods:

• Please clarify why Rwanda was not included in the quantitative part of the study.

• Please indicate whether the questionnaires used in this study (other than the CSTI, which was developed here) have been validated for the respective cultural and linguistic contexts in which they were applied (Uganda, Tanzania, Rwanda, and Kenya).

• Please list the subscales of the Clinical Aspects of Historical Trauma Questionnaire in the methodology section. In addition, please clarify what is meant by the term “clinical aspects of historical trauma.”

• Under which ethical approvals was data collection in Tanzania and Uganda conducted? Please clarify why local ethical approval appears to have been obtained only for Kenya and Rwanda.

• Participants were included if they had “past traumatic experiences.” However, the type and severity of trauma are not clearly operationalized. The authors should clarify how trauma exposure was defined and assessed.

• Several items in the scale appear to be unrelated to trauma. For example, items such as “I am proud of my achievements” or “I believe everything is possible” might resemble general well-being or personal growth items rather than trauma-related symptoms. The conceptual rationale for including such items should be clarified.

• East Africa is culturally diverse. Combining four countries may obscure important differences in religion, conflict history, and trauma exposure. The manuscript should discuss cross-cultural variability more critically.

Results:

• Some tables are difficult to interpret, for example Table 7 (HTMT values) and Table 6 (item analysis). Clearer formatting and labeling would improve readability.

• I do not understand the age categories used in the manuscript. For example, the groups 29–44 and 41–55 appear to overlap. Please clarify the rationale for dividing the sample into these categories. I also do not understand the division into three age groups presented in Table 2. Please explain why these specific age groupings were chosen instead of reporting mean age and standard deviation.

• Relatedly, the manuscript does not report standard deviations (SDs) for several variables. Please clarify why these are not included, as SDs would help readers better understand the distribution of the data.

Discussion:

• The manuscript states: “Participants described how traumatic experiences extend beyond the individual level to affect the entire family.” This statement seems to imply that such family-level effects are specific to people in Sub-Saharan Africa. However, although these dynamics may not be explicitly reflected in diagnostic frameworks such as ICD-10 or ICD-11, this does not mean that patients in Europe do not experience similar family-level consequences of trauma. A more balanced discussion would be helpful. Are there studies from European contexts examining how PTSD-related suffering extends beyond the individual to affect the family system? From my clinical experience, such family dynamics are also highly relevant in European settings.

• The authors refer to PTSD and cPTSD in the introduction, yet this distinction is not clearly reflected in the discussion of cultural scripts. It would be helpful to clarify whether the distinction between simple and complex post-traumatic experiences plays a role within the concept of cultural scripts. This may be particularly relevant for aspects such as interpersonal relationship difficulties, which are central features of complex trauma presentations.

I recommend a Major Revision

The manuscript addresses an important topic and has strong potential. However, substantial revisions are required to:

• improve conceptual clarity

• strengthen methodological transparency

• address sampling bias

• refine statistical reporting

• correct language and presentation issues.

With these improvements, the study could make a valuable contribution to culturally informed trauma research and will, in my opinion, become a very important and widely cited paper that addresses a significant gap in global and transcultural trauma research.

Reviewer #3: I congratulate the authors to their manuscript. It advances the discussion of the PTSD concept considerably. The challenge of this manuscript is that is very complex and word limit needs to be balanced with reporting of essential information. I tried to provide some comments how to further develop this manuscript.

Abstract:

- It is confusing for a reader the fact that the pre-CSTI had 71 items is first presented in Methods and then, again presented as if a new information in Results. It might be sufficient to present the number of items in Results.

Introduction:

- Line 33 ff: Please state here the aims and if relevant hypotheses of the qualitative and quantitative studies

Methods:

- Line 43 ff: Some aspects of the qualitative study remain vague, e.g. who conducted the interviews and the analysis, the languages and settings that were involved etc. How was your approach in the analysis re the different languages, e.g. did you translate all scripts to and do the qualitative work in one of the languages?

- Line 62 – 65: Please state clearly for what reason you used social media.

- Line 62 ff: It remains vague how the quantitative data assessment took place, e.g. how participants filled the questionnaires, languages used etc.

- Line 69 ff: It would be helpful to reorder the description of your measures and to assign them to the qualitative and quantitative study.

- Line 79 ff: The description of your interview protocol guide is very brief. Please refer to the theoretical approach you followed, the way how your interview guideline was developed etc. The qualitative work needs to be better described, i.e. what were the guiding questions for the coders. The systematic how items were developed based on the qualitative data remains unclear, please elaborate on that.

- Line 74 ff: It is confusing that you present the result of the study, the final CSTI, in the methods section as if it was employed like the other questionnaires. I recommend that you describe the final CSTI at the end of the results section.

- Line 82 ff: Please provide some information on whether the employed quantitative instruments can be considered culturally appropriate and on how you made sure that validated and comparable language versions were available.

- Please find a way to clearly name the two meanings of discriminant validity in your study.

Results:

Table 1 and Table 2: The reporting of the mean of the variable age is not adequate in this table format, especially as the coefficient is in the column “Frequency”; furthermore, the SD needs to be reported, too. I recommend to restructure the table or report it in the text.

- After Line 153 the line count stopped.

- Table 3: Very important information; but it might be moved to an electronic annex.

- Interpretation of the CSTs in the different categories: E.g. you write re the third category “These accounts illustrate how, in contrast to findings from Western contexts, trauma in East African settings can deeply disrupt family functioning and contribute to a loss of hope within the family unit.” These statements seem to better fit into the discussion section. E.g. concerning the third category, it is a matter of discussion whether the disruption of families and the loss of hope are specific or universal cultural phenomena.

- EFA factor extraction: Usually, you first perform the tests that guide you on factor number and then you perform an EFA with this number of factors. Please justify your approach.

- Sample used for EFA and CFA: Did you use the same sample for both methods? Usually separate samples are recommended, e.g. to split the original sample (2/3 vs 1/3). Please justify your approach.

- Table 6: The table and its information is difficult to understand, please clarify. Especially the meaning of the coefficients should be explained (e.g. in the methods section), e.g. “Item alpha value” vs “alpha” and why in “Dimension” TS and SS are mentioned; what means “general reliability”?

- Table 7: please provide the meaning of the lines.

Discussion:

- The discussion would profit from the point of view that the categories of CSTs detected in the qualitative study also relate to the concepts behind the DSM symptom categories. The universal vs. specific cultural nature of symptoms needs to be commented on.

Typos and grammar

- Line 12 “was”

- Line 44 verb missing

- Line 63 verb missing

- Line 150: Please write “Qualitative results”

**********

what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review?  For information about this choice, including consent withdrawal, please see our Privacy Policy

Reviewer #1: Yes:  Madison Fertig

Reviewer #2: No

Reviewer #3: No

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

To ensure your figures meet our technical requirements, please review our figure guidelines: https://journals.plos.org/plosone/s/figures

You may also use PLOS’s free figure tool, NAAS, to help you prepare publication quality figures: https://journals.plos.org/plosone/s/figures#loc-tools-for-figure-preparation.

NAAS will assess whether your figures meet our technical requirements by comparing each figure against our figure specifications.

Attachment

Submitted filename: PLOS One- Review.docx

pone.0358482.s007.docx (15.7KB, docx)

Decision Letter 1

Inga Schalinski

15 Aug 2026

Dear Dr. Mutuyimana,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Sep 29 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

  • A letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols.

As the corresponding author, your ORCID iD is verified in the submission system and will appear in the published article. PLOS supports the use of ORCID, and we encourage all coauthors to register for an ORCID iD and use it as well. Please encourage your coauthors to verify their ORCID iD within the submission system before final acceptance, as unverified ORCID iDs will not appear in the published article. Only  the individual author can complete the verification step; PLOS staff cannot  verify ORCID iDs on behalf of authors.

We look forward to receiving your revised manuscript.

Kind regards,

Inga Schalinski

Academic Editor

PLOS One

Journal Requirements:

If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise.

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

Reviewer #2: All comments have been addressed

Reviewer #3: (No Response)

**********

2. Is the manuscript technically sound, and do the data support the conclusions??>

Reviewer #2: Yes

Reviewer #3: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #2: Yes

Reviewer #3: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #2: Yes

Reviewer #3: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #2: Yes

Reviewer #3: Yes

**********

Reviewer #2: I am pleased to recommend acceptance of the current manuscript for publication. The manuscript has improved substantially and is now appropriate for publication. Only a few minor editorial issues should be corrected:

• Line 30: Remove the extra “AND“.

• Line 426: The term “Western Samples” is duplicated in the sentence.

Subject to these minor corrections, I support publication of the manuscript.

Reviewer #3: Thank you for addressing my comments. The manuscript has been improved substantially.

I just have some minor comments.

Abstract:

Please mention in the Methods paragraph clearly that the quantitative survey was an online survey. EG. “In an online survey, participants completed the pre-CSTI and additional measures…”

Line 156: Please make it clearer that you used a online questionnaire by writing “The participants used a google form link to fill out the online questionnaire.”

Line 161: The instructions for subjects should be described here too.

Lines 280 ff: “These accounts illustrate how, in contrast to findings from Western contexts, trauma in East African settings can deeply disrupt family functioning and contribute to a loss of hope within the family unit.”

Again, I comment on the phrase “in contrast to findings from Western settings” which is a claim not being supported with literature in this context. I doubt that there is a contrast between findings from Western contexts and East African settings in this aspect as long as you don’t provide clear evidence. From my personal experience as expert I see every day how trauma disrupts family functioning in a western context. Maybe you want to say that this symptom dimension is not reflected in the DSM and ICD sets of symptom criteria; I would agree on that. Amyway, you should support this claim with literature, but in the results section this is not the right place for it. Better place this claim and its discussion into the discussion section and reword the respective sentence to

“These accounts illustrate how trauma in East African settings can deeply disrupt family functioning and contribute to a loss of hope within the family unit" and eventually " – what is not reflected in DSM and ICD.”

Lines 336: You may reference Table 1 in this paragraph.

Line 336 and Table 1: For me unclear why you included item No 7 as sleeping poblems are already included in the DSM and ICD lists of symptoms. Isn’t the overall aim of the CSTI to contribute additional symptoms? Please explain why you decided to include the sleeping problems into the CSTI.

Line 354, Table 2: The labeling of columns is confusing – which label refers to which column?

Line 431: “the CFA only confirm four categories”. Is this a mistake as you report 5 categories? Please explain better.

Supplemental Material 4: The instructions and explanations for subjects about to fill the CSTI should be reported here, too.

Minor comments:

Line 30: “and generally“ seems to be there by mistake as it does not make sense

Line 71: “;“

Line 212: Please introduce here the abbreviation EFA that you use below.

**********

what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review?  For information about this choice, including consent withdrawal, please see our Privacy Policy

Reviewer #2: No

Reviewer #3: No

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

To ensure your figures meet our technical requirements, please review our figure guidelines: https://journals.plos.org/plosone/s/figures

You may also use PLOS’s free figure tool, NAAS, to help you prepare publication quality figures: https://journals.plos.org/plosone/s/figures#loc-tools-for-figure-preparation.

NAAS will assess whether your figures meet our technical requirements by comparing each figure against our figure specifications.

Decision Letter 2

Inga Schalinski

2 Sep 2026

Eastern African Expressions of Suffering: a new Cultural Scripts of Trauma Inventory

PONE-D-25-53823R2

Dear Dr. Mutuyimana,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

An invoice will be generated when your article is formally accepted. Please note, if your institution has a publishing partnership with PLOS and your article meets the relevant criteria, all or part of your publication costs will be covered. Please make sure your user information is up-to-date by logging into Editorial Manager at Editorial Manager® and clicking the ‘Update My Information' link at the top of the page. For questions related to billing, please contact billing support.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

Kind regards,

Inga Schalinski

Academic Editor

PLOS One

Additional Editor Comments (optional):

Reviewers' comments:

Acceptance letter

Inga Schalinski

PONE-D-25-53823R2

PLOS One

Dear Dr. Mutuyimana,

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS One. Congratulations! Your manuscript is now being handed over to our production team.

At this stage, our production department will prepare your paper for publication. This includes ensuring the following:

* All references, tables, and figures are properly cited

* All relevant supporting information is included in the manuscript submission,

* There are no issues that prevent the paper from being properly typeset

You will receive further instructions from the production team, including instructions on how to review your proof when it is ready. Please keep in mind that we are working through a large volume of accepted articles, so please give us a few days to review your paper and let you know the next and final steps.

Lastly, if your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

You will receive an invoice from PLOS for your publication fee after your manuscript has reached the completed accept phase. If you receive an email requesting payment before acceptance or for any other service, this may be a phishing scheme. Learn how to identify phishing emails and protect your accounts at https://explore.plos.org/phishing.

If we can help with anything else, please email us at customercare@plos.org.

Thank you for submitting your work to PLOS One and supporting open access.

Kind regards,

PLOS One Editorial Office Staff

on behalf of

Dr. Inga Schalinski

Academic Editor

PLOS One

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 File. Interview Guide.

    (XLSX)

    pone.0358482.s001.xlsx (9.4KB, xlsx)
    S2 File. CST code book final.

    (XLSX)

    pone.0358482.s002.xlsx (16.8KB, xlsx)
    S3 File. Inclusivity in global research.

    (DOCX)

    pone.0358482.s003.docx (68.1KB, docx)
    S4 File. List of mapped cultural scripts of trauma suffering: initial pool of items.

    (DOCX)

    pone.0358482.s004.docx (25.4KB, docx)
    S5 File. Cultural Script of Trauma Inventory (CSTI).

    (DOCX)

    pone.0358482.s005.docx (18.4KB, docx)
    S6 File. Complete description of qualitative dataset.

    (DOCX)

    pone.0358482.s006.docx (17.8KB, docx)
    Attachment

    Submitted filename: PLOS One- Review.docx

    pone.0358482.s007.docx (15.7KB, docx)
    Attachment

    Submitted filename: Response to Reviewers comments.docx

    pone.0358482.s008.docx (33.6KB, docx)

    Data Availability Statement

    Quantitative data are available in the public repository: https://doi.org/10.5281/zenodo.20385027. Qualitative date restrictions details: data contain potentially identifying and sensitive trauma survivors information The restrictions is imposed by College of Medicine and Health Sceinces Ethical Committee (researchcenter@ur.ac.rw) Daystar Univesity Institutional Scientific and Ethics Review Committee (info@daystar.ace.ke), and University of Dar es Salaam Ethical Committee (vc@admin.udsm.ac.tz).


    Articles from PLOS One are provided here courtesy of PLOS

    RESOURCES