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Alzheimer's Research & Therapy logoLink to Alzheimer's Research & Therapy
. 2026 Sep 26;18:213. doi: 10.1186/s13195-026-02196-0

Correction: Higher phosphorylated tau levels predict cognitive decline and amyloid-related imaging abnormalities during lecanemab treatment: clinical practice data

Moeko Noguchi-Shinohara 1,#, Takahiro Yoshinobu 1,#, Taro Ozaki 1, Daiki Muramatsu 1, Ayano Shima 1, Yasuhiro Sakashita 1, Yasutake Tada 1, Hiroki Yamaguchi 1, Junji Komatsu 1, Tokuhei Ikeda 1, Kenjiro Ono 1,✉
PMCID: PMC13616116  PMID: 42800883

Correction: Alz Res Therapy 17, 251 (2025)

https://doi.org/10.1186/s13195-025-01912-6

Following publication of the original article [1], the 95%CI “19.98 (2.43-163.81.43.81)” and “18.39 (1.91-176.33.91.33)”of Models 4 and 5 for High ptau group in Table 3 were incorrect, and should have been “19.98 (2.43-163.81)” and “18.39 (1.91-176.33)”. The corrected Table 3 is given below.

Table 3.

Demographics and cognitive tests results of patients at baseline and follow-up, who initiated lecanemab treatment

No. of ARIA cases/patients Model 1 OR (95%CI) Model 2 OR (95%CI) Model 3 OR (95%CI) Model 4 OR (95%CI) Model 5 OR (95%CI)
Low ptau group 2/36 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference)
High ptau group 10/34 8.69 (1.62-46.43) 7.83 (1.44-42.59) 7.79 (1.43-42.45) 19.98 (2.43-163.81) 18.39 (1.91-176.33)

Abbreviations: CI confidence interval, OR odds ratio, ptau phosphorylated tau

Model 1 was adjusted for age and sex

Model 2 was adjusted for age, sex, and APOE4 status

Models 3, 4, and 5 were adjusted for global clinical dementia rating score, amyloid PET centiloid value, number of microbleeds on baseline MRI in addition to the covarites in Model 2, respectively

The original article [1] has been corrected.

Footnotes

Moeko Noguchi-Shinohara and Takahiro Yoshinobu contributed equally to this work.

Reference

  • 1.Noguchi-Shinohara M, Yoshinobu T, Ozaki T, et al. Higher phosphorylated tau levels predict cognitive decline and amyloid-related imaging abnormalities during lecanemab treatment: clinical practice data. Alz Res Therapy. 2025;17:251. 10.1186/s13195-025-01912-6. [DOI] [PMC free article] [PubMed] [Google Scholar]

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