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. 2026 Sep 28;22(9):e1014636. doi: 10.1371/journal.ppat.1014636

Correction: Directed evolution of a stem-helix–targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity

The PLOS Pathogens Staff
PMCID: PMC13618938  PMID: 42804424

The references 18 through 23 were out of order and reference 52 was omitted. Please see the corrected order for references 18 through 23 and reference 52 below.

  • 18. Parren PW, Burton DR. The antiviral activity of antibodies in vitro and in vivo. Adv Immunol. 2001;77:195–262. https://doi.org/10.1016/s0065-2776(01)77018-6 PMID: 11293117

  • 19. Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, et al. Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody. Science. 2021;371(6531):823–9. https://doi.org/10.1126/science.abf4830 PMID: 33495307

  • 20. Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, et al. A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection. Sci Transl Med. 2022;14(637):eabi9215. https://doi.org/10.1126/scitranslmed.abi9215 PMID:35133175

  • 21. Pinto D, Sauer MM, Czudnochowski N, Low JS, Tortorici MA, Housley MP, et al. Broad betacoronavirus neutralization by a stem helix-specific human antibody. Science. 2021;373(6559):1109–16. https://doi.org/10.1126/science.abj3321 PMID: 34344823

  • 22. Dacon C, Peng L, Lin T-H, Tucker C, Lee C-CD, Cong Y, et al. Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe. 2023;31(1):97–111.e12. https://doi.org/10.1016/j.chom.2022.10.010 PMID: 36347257

  • 23. Henikoff S, Henikoff JG. Amino acid substitution matrices from protein blocks. Proc Natl Acad Sci U S A. 1992;89(22):10915–9. https://doi.org/10.1073/pnas.89.22.10915 PMID: 1438297

  • 52. Williams CJ, Headd JJ, Moriarty NW, Prisant MG, Videau LL, Deis LN, et al. MolProbity: More and better reference data for improved all-atom structure validation. Protein Sci. 2018;27(1):293–315. Epub 20171127. https://doi.org/10.1002/pro.3330 PMID: 29067766

The publisher apologizes for the error.

Reference

  • 1.Zhou P, Yuan M, Zhang Y, Limbo O, Song G, Zhao F, et al. Directed evolution of a stem-helix–targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity. PLoS Pathog. 2026;22(8):e1014393. doi: 10.1371/journal.ppat.1014393 [DOI] [PMC free article] [PubMed] [Google Scholar]

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