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. 1960 Jun;151(3):539–550. doi: 10.1113/jphysiol.1960.sp006458

Circulatory, respiratory and metabolic responses to isopropylnoradrenaline in man

A F Cobbold, Jean Ginsburg, A Paton
PMCID: PMC1363282  PMID: 13810786

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AVIADO D. M., Jr, WNUCK A. L., DE BEER E. J. The effects of sympathomimetic drugs on renal vessels. J Pharmacol Exp Ther. 1958 Nov;124(3):238–244. [PubMed] [Google Scholar]
  2. BARCROFT H., COBBOLD A. F. The action of adrenaline on muscle blood flow and blood lactate in man. J Physiol. 1956 May 28;132(2):372–378. doi: 10.1113/jphysiol.1956.sp005530. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BARCROFT H., KONZETT H. On the actions of noradrenaline, adrenaline and isopropyl noradrenaline on the arterial blood pressure, heart rate and muscle blood flow in man. J Physiol. 1949 Dec 15;110(1-2):194–204. doi: 10.1113/jphysiol.1949.sp004431. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BEARN A. G., BILLING B., SHERLOCK S. The effect of adrenaline and noradrenaline on hepatic blood flow and splanchnic carbohydrate metabolism in man. J Physiol. 1951 Dec 28;115(4):430–441. doi: 10.1113/jphysiol.1951.sp004679. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BRADLEY R. D., GASKELL P., HOLLAND W. W., DE LEE G. J., YOUNG I. M. The acid-base changes in arterial blood during adrenaline hyperpnoea in man. J Physiol. 1954 May 28;124(2):213–218. doi: 10.1113/jphysiol.1954.sp005100. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. COBBOLD A. F., VASS C. C. Responses of muscle blood vessels to intra-arterially and intravenously administered noradrenaline. J Physiol. 1953 Apr 28;120(1-2):105–114. doi: 10.1113/jphysiol.1953.sp004876. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. GARB S., PENNA M., GANZ A. Effects of epinephrine, norepinephrine and isopropylarterenol on the isolated auricles of four mammalian species. Am J Physiol. 1956 May;185(2):332–336. doi: 10.1152/ajplegacy.1956.185.2.332. [DOI] [PubMed] [Google Scholar]
  8. GREEN H. D., DEAL C. P., Jr, BARDHANABAEDYA S., DENISON A. B., Jr The effects of adrenergic substances and ischemia on the blood flow and peripheral resistance of the canine mesenteric vascular bed before and during adrenergic blockade. J Pharmacol Exp Ther. 1955 Jan;113(1):115–123. [PubMed] [Google Scholar]
  9. GREEN H. D., SHEARIN W. T., Jr, JACKSON T. W., KEACH L. M., DENISON A. B., Jr Isopropylnorepinephrine blockade of epinephrine reversal. Am J Physiol. 1954 Nov;179(2):287–294. doi: 10.1152/ajplegacy.1954.179.2.287. [DOI] [PubMed] [Google Scholar]
  10. Gaddum J. H., Peart W. S., Vogt M. The estimation of adrenaline and allied substances in blood. J Physiol. 1949 Jun 15;108(4):467–481. doi: 10.1113/jphysiol.1949.sp004350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Haslewood G. A., Strookman T. A. A method for the estimation of "true" sugar in 0.05 ml. of blood. Biochem J. 1939 Jun;33(6):920–923. doi: 10.1042/bj0330920. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. LANDS A. M., HOWARD J. W. A comparative study of the effects of 1-arterenol, epinephrine and isopropylarterenol on the heart. J Pharmacol Exp Ther. 1952 Sep;106(1):65–76. [PubMed] [Google Scholar]
  13. LANDS A. M., LUDUENA F. P., TULLAR B. F. The pharmacologic activity of the optical isomers of isopropylarterenol (isuprel) compared with that of the optically inactive analog 1-(3,4-dihydroxyphenyl)-2-isoprophylaminoethane HCI. J Pharmacol Exp Ther. 1954 Aug;111(4):469–474. [PubMed] [Google Scholar]
  14. LANDS A. M., TAINTER M. L. The effect of changes in molecular configuration on inhibitory sympathominetic action. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1953;219(1-2):76–90. doi: 10.1007/BF00246253. [DOI] [PubMed] [Google Scholar]
  15. LOCKETT M. F. Identification of an isoprenaline-like substance in extracts of adrenal glands. Br J Pharmacol Chemother. 1954 Dec;9(4):498–505. doi: 10.1111/j.1476-5381.1954.tb00868.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. LOCKETT M. F. The transmitter released by stimulation of the bronchial sympathetic nerves of cats. Br J Pharmacol Chemother. 1957 Mar;12(1):86–96. doi: 10.1111/j.1476-5381.1957.tb01367.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. RUSHMER R. F., SMITH O. A., Jr Cardiac control. Physiol Rev. 1959 Jan;39(1):41–68. doi: 10.1152/physrev.1959.39.1.41. [DOI] [PubMed] [Google Scholar]
  18. RUSHMER R. F., WEST T. C. Role of autonomic hormones on left ventricular performance continuously analyzed by electronic computers. Circ Res. 1957 May;5(3):240–246. doi: 10.1161/01.res.5.3.240. [DOI] [PubMed] [Google Scholar]
  19. WALTERS P. A., Jr, COOPER T. W., DENISON A. B., Jr, GREEN H. D. Dilator responses to isoproterenol in cutaneous and skeletal muscle vascular beds; effects of adrenergic blocking drugs. J Pharmacol Exp Ther. 1955 Nov;115(3):323–328. [PubMed] [Google Scholar]
  20. WHELAN R. F. Vasodilatation in human skeletal muscle during adrenaline infusions. J Physiol. 1952 Dec;118(4):575–587. doi: 10.1113/jphysiol.1952.sp004819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. WHELAN R. F., YOUNG I. M. The effect of adrenaline and noradrenaline infusions on respiration in man. Br J Pharmacol Chemother. 1953 Mar;8(1):98–102. doi: 10.1111/j.1476-5381.1953.tb00759.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. YOUNG I. M. Some observations on the mechanism of adrenaline hyperpnoea. J Physiol. 1957 Aug 6;137(3):374–395. doi: 10.1113/jphysiol.1957.sp005820. [DOI] [PMC free article] [PubMed] [Google Scholar]

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