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. 2026 Feb 27;147(22):2698. doi: 10.1182/blood.2026033814

Rust BJ, Kean LS, Colonna L, Brandenstein KE, Poole NH, Obenza W, Enstrom MR, Maldini CR, Ellis GI, Fennessey CM, Huang M-L, Keele BF, Jerome KR, Riley JL, Kiem H-P, Peterson CW. Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates. Blood. 2020;136(15):1722-1734.

PMCID: PMC13639452  PMID: 41734335

This article has been retracted at the request of the authors; please see Elsevier’s Article Correction, Retraction and Removal Policy (https://www.elsevier.com/about/policies-and-standards/article-withdrawal).

The study's authors conducted a reevaluation of their work after being unable to repeat the findings with a new data set. They report that, upon this reevaluation, the published flow cytometry conflicts with new chimeric antigen receptor (CAR) polymerase chain reaction data, thus nullifying the original hypothesis.

The Editors acknowledge and appreciate the transparency of the authors for bringing this issue to the journal’s attention.

Authors Blake J. Rust, Leslie S. Kean, Lucrezia Colonna, Willimark Obenza, Gavin I. Ellis, Christine M. Fennessey, Brandon F. Keele, Keith R. Jerome, James L. Riley, Hans-Peter Kiem, and Christopher W. Peterson approve the retraction. Authors Katherine E. Brandenstein, Nikhita H. Poole, Mark R. Enstrom, Colby R. Maldini, and Meei-Li Huang did not respond.

A follow-up study related to this retracted paper has now been published in Blood (https://dx.doi.org/10.1182/blood.2025032142).


Articles from Blood are provided here courtesy of The American Society of Hematology

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