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. 1967 May;190(1):229–240. doi: 10.1113/jphysiol.1967.sp008204

Some observations on `autoregulatory escape' in cat intestine

Rosemary Baker, D Mendel
PMCID: PMC1365415  PMID: 6038024

Abstract

1. `Autoregulatory escape' (Folkow, Lewis, Lundgren, Mellander & Wallentin, 1964a) in which intestinal blood flow escapes from the constrictor influence of splanchnic nerve stimulation, was investigated in the cat. Measurements were made of intestinal blood flow, movements and portal venous pH and oxygen content.

2. `Autoregulatory escape' was observed with sympathetic nerve stimulation and noradrenaline infusion. It did not occur during haemorrhage.

3. The recovery of flow during noradrenaline infusion could not be explained by changes in intestinal motility or loss of effect of noradrenaline due to changes in portal venous hydrogen ion concentration.

4. During a noradrenaline infusion there was a reduction in oxygen consumption associated with a fall in blood flow. During the period of `autoregulatory escape', however, oxygen consumption increased. The significance of these observations is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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