Abstract
1. A pouch has been prepared consisting of a part of the wall of the left atrium together with the left pulmonary vein—atrial junctions.
2. An increase of perfusion pressure in the pouch caused a reflex increase in heart rate.
3. The afferent path of the reflex was in the vagus nerves and the efferent path was in the sympathetic nerves.
4. The receptors most likely to be stimulated by an increase in pressure in the pouch are those receptors situated in the subendocardium of the pulmonary vein—left atrial junctions.
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Selected References
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- BOURA A. L., GREEN A. F. The actions of bretylium: adrenergic neurone blocking and other effects. Br J Pharmacol Chemother. 1959 Dec;14:536–548. doi: 10.1111/j.1476-5381.1959.tb00961.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- COLERIDGE J. C., HEMINGWAY A., HOLMES R. L., LINDEN R. J. The location of atrial receptors in the dog: a physiological and histological study. J Physiol. 1957 Apr 3;136(1):174–197. doi: 10.1113/jphysiol.1957.sp005750. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEDSOME J. R., LINDEN R. J. A REFLEX INCREASE IN HEART RATE FROM DISTENSION OF THE PULMONARY-VEIN-ATRIAL JUNCTIONS. J Physiol. 1964 Apr;170:456–473. doi: 10.1113/jphysiol.1964.sp007343. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEDSOME J. R., LINDEN R. J., NORMAN J. THE USE OF SYMPATHETIC BETA-RECEPTOR BLOCKING AGENTS IN THE INVESTIGATION OF REFLEX CHANGES IN HEART RATE. Br J Pharmacol Chemother. 1965 Jun;24:781–788. doi: 10.1111/j.1476-5381.1965.tb01634.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEDSOME J. R., LINDEN R. J. THE EFFECT OF BRETYLIUM TOSYLATE ON SOME CARDIOVASCULAR REFLEXES. J Physiol. 1964 Apr;170:442–455. doi: 10.1113/jphysiol.1964.sp007342. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LINDEN R. J., LEDSOME J. R., NORMAN J. SIMPLE METHODS FOR THE DETERMINATION OF THE CONCENTRATIONS OF CARBON DIOXIDE AND OXYGEN IN BLOOD. Br J Anaesth. 1965 Feb;37:77–88. doi: 10.1093/bja/37.2.77. [DOI] [PubMed] [Google Scholar]
- MIZERES N. J. The origin and course of the cardioaccelerator fibers in the dog. Anat Rec. 1958 Nov;132(3):261–279. doi: 10.1002/ar.1091320304. [DOI] [PubMed] [Google Scholar]
- McCOOK R. D., PEISS C. N. An integrating cardiotachometer for optical or pen recording. J Appl Physiol. 1959 May;14(3):473–474. doi: 10.1152/jappl.1959.14.3.473. [DOI] [PubMed] [Google Scholar]
- Norman J., Ledsome J. R., Linden R. J. A system for the measurement of respiratory and acid-base parameters in blood. Br J Anaesth. 1965 Jul;37(7):466–479. doi: 10.1093/bja/37.7.466. [DOI] [PubMed] [Google Scholar]