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. 1968 Feb;194(3):627–644. doi: 10.1113/jphysiol.1968.sp008429

Observation of changes in volume of a congested limb as a means of studying the behaviour of capacity vessels

B L Ardill, V M Bhatnagar, P H Fentem
PMCID: PMC1365657  PMID: 4295263

Abstract

1. Experiments have been performed to determine whether the volume of a forearm congested by a cuff inflated to a low pressure (15-30 mm Hg) reflects active changes in the vascular capacity of the part while remaining relatively insensitive to the passive effects of changes in perfusion.

2. Conditions were chosen in which existing evidence suggests that blood flow and capacity vary independently of each other.

3. The results of these experiments suggested that active changes in capacity can be studied by the continuous observation of the volume of a congested limb, provided that the associated change in blood flow is a reduction from the basal level and is not an increase above the basal level.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ardill B. L., Bannister R. G., Fentem P. H., Greenfield A. D. Circulatory responses of supine subjects to the exposure of parts of the body below the xiphisternum to subatmospheric pressure. J Physiol. 1967 Nov;193(1):57–72. doi: 10.1113/jphysiol.1967.sp008343. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BRAUNWALD E., ROSS J., Jr, KAHLER R., GAFFNEY T. E., GOLDBLATT A., MASON D. T. Reflex control of the systemic venous bed. Effects on venous tone of vasoactive drugs, and of baroreceptor and chemoreceptor stimulation. Circ Res. 1963 May;2:539–552. doi: 10.1161/01.res.12.5.539. [DOI] [PubMed] [Google Scholar]
  3. Bannister R., Ardill L., Fentem P. Defective autonomic control of blood vessels in idiopathic orthostatic hypotension. Brain. 1967 Dec;90(4):725–746. doi: 10.1093/brain/90.4.725. [DOI] [PubMed] [Google Scholar]
  4. Bevegård B. S., Shepherd J. T. Effect of local exercise of forearm muscles on forearm capacitance vessels. J Appl Physiol. 1965 Sep;20(5):968–974. doi: 10.1152/jappl.1965.20.5.968. [DOI] [PubMed] [Google Scholar]
  5. Brown E., Goei J. S., Greenfield A. D., Plassaras G. C. Circulatory responses to simulated gravitational shifts of blood in man induced by exposure of the body below the iliac crests to sub-atmospheric pressure. J Physiol. 1966 Apr;183(3):607–627. doi: 10.1113/jphysiol.1966.sp007887. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Brown E., Greenfield D. M., Goei J. S., Plassaras G. Filling and emptying of the low-pressure blood vessels of the human forearm. J Appl Physiol. 1966 Mar;21(2):573–582. doi: 10.1152/jappl.1966.21.2.573. [DOI] [PubMed] [Google Scholar]
  7. DEPASQUALE N. P., BURCH G. E. EFFECT OF ANGIOTENSIN II ON THE INTACT FOREARM VEINS OF MAN. Circ Res. 1963 Sep;13:239–245. doi: 10.1161/01.res.13.3.239. [DOI] [PubMed] [Google Scholar]
  8. FEWINGS J. D., HODGE R. L., SCROOP G. C., WHELAN R. F. THE EFFECTS OF BETHANIDINE ON THE PERIPHERAL CIRCULATION IN MAN. Br J Pharmacol Chemother. 1964 Aug;23:115–122. doi: 10.1111/j.1476-5381.1964.tb01572.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. FOLKOW B., JOHANSSON B., MELLANDER S. The comparative effects of angiotensin and noradrenaline on consecutive vascular sections. Acta Physiol Scand. 1961 Oct;53:99–104. doi: 10.1111/j.1748-1716.1961.tb02267.x. [DOI] [PubMed] [Google Scholar]
  10. GREENFIELD A. D., WHITNEY R. J., MOWBRAY J. F. Methods for the investigation of peripheral blood flow. Br Med Bull. 1963 May;19:101–109. doi: 10.1093/oxfordjournals.bmb.a070026. [DOI] [PubMed] [Google Scholar]
  11. HADDY F. J., MOLNAR J. I., BORDEN C. W., TEXTER E. C., Jr Comparison of direct effects of angiotensin and other vasoactive agents on small and large blood vessels in several vascular beds. Circulation. 1962 Jan;25:239–246. doi: 10.1161/01.cir.25.1.239. [DOI] [PubMed] [Google Scholar]
  12. MASON D. T., MELMON K. L. EFFECTS OF BRADYKININ ON FOREARM VENOUS TONE AND VASCULAR RESISTANCE IN MAN. Circ Res. 1965 Aug;17:106–113. doi: 10.1161/01.res.17.2.106. [DOI] [PubMed] [Google Scholar]
  13. OCHSNER A., Jr, COLP R., Jr, BURCH G. E. Normal blood pressure in the superficial venous system of man at rest in the supine position. Circulation. 1951 May;3(5):674–680. doi: 10.1161/01.cir.3.5.674. [DOI] [PubMed] [Google Scholar]
  14. SHARPEY-SCHAFER E. P., GINSBURG J. Humoral agents and venous tone. Effects of catecholamines, 5-hydroxytryptamine, histamine, and nitritex. Lancet. 1962 Dec 29;2(7270):1337–1340. doi: 10.1016/s0140-6736(62)91018-8. [DOI] [PubMed] [Google Scholar]
  15. SHARPEY-SCHAFER E. P. Venous tone: effects of reflex changes, humoral agents and exercise. Br Med Bull. 1963 May;19:145–148. doi: 10.1093/oxfordjournals.bmb.a070034. [DOI] [PubMed] [Google Scholar]
  16. SHEPHERD J. T. CHANGES IN TONE OF LIMB VEINS DURING SUPINE EXERCISE. J Appl Physiol. 1965 Jan;20:1–8. doi: 10.1152/jappl.1965.20.1.1. [DOI] [PubMed] [Google Scholar]
  17. SUTTER M. C. THE PHARMACOLOGY OF ISOLATED VEINS. Br J Pharmacol Chemother. 1965 Jun;24:742–751. doi: 10.1111/j.1476-5381.1965.tb01630.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Samueloff S. L., Browse N. L., Shepherd J. T. Response of capacity vessels in human limbs to head-up tilt and suction on lower body. J Appl Physiol. 1966 Jan;21(1):47–54. doi: 10.1152/jappl.1966.21.1.47. [DOI] [PubMed] [Google Scholar]

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