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. 1962 Nov;2(6):451–463. doi: 10.1016/s0006-3495(62)86867-2

Effects of Decay of Incorporated H3-Thymidine on Bacteria

Stanley Person, Hazel Leah Lewis
PMCID: PMC1366412  PMID: 19431318

Abstract

The killing efficiency due to the decay of incorporated H3-thymidine in three mutants of E. coli strain 15: 15T-, 15T-L-, and 15T-U- has been determined. This efficiency is comparable to that previously determined by others for P32 decay. The killing efficiency has been determined as a function of H3-thymidine specific activity, storage media and storage temperature. We have observed a latent killing effect that causes lethality under certain conditions. The kinetics of latent killing have been examined at several temperatures. Finally, mutation production induced by H3-thymidine decays was shown to occur. The results are consistent with the idea that inactivation and mutations may be caused by a process in the nuclear transmutation that is not associated with β-particle ionization damage.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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