Table 2.
Evaluation of PTX, CAP, and their combination on hematological parameters in female Balb/c mice
| Control | PTX 5 mg/kg | CAP 10 mg/kg | PTX 5 mg/kg + CAP 5 mg/kg | PTX 5 mg/kg + CAP 10 mg/kg | |
|---|---|---|---|---|---|
| RBC, 106/µL | 7.01 ± 0.2 | 7.47 ± 0.2 | 8.5 ± 0.5 | 5.45 ± 0.2 | 7.46 ± 0.1 |
| WBC, 103/µL | 7 ± 0.2 | 7 ± 0.1 | 7.4 ± 0.3 | 5.4 ± 0.3 | 7.4 ± 0.2 |
| Hemoglobin, g/dL | 10.1 ± 0.1 | 10.4 ± 0.1 | 12.6 ± 0.3 | 7.9 ± 0.1 | 11.2 ± 0.3 |
| Hematocrit, % | 35.1 ± 0.5 | 36.3 ± 0.7 | 44.2 ± 1.1 | 27.5 ± 0.2 | 39.3 ± 0.6 |
| PLT, 103/µL | 761 ± 31 | 587 ± 16 | 493 ± 22 | 646 ± 52 | 714 ± 15 |
| Neutrophils, % | 83 ± 8 | 80 ± 4 | 89 ± 4 | 87 ± 9 | 86 ± 3 |
| Lymphocyte, % | 18 | 20 | 10 | 12 | 15 |
| Monocyte, % | 1 | * | * | * | 1 |
| M.C.V, fL | 50.2 ± 1.1 | 48.7 ± 1.2 | 52.0 ± 1.0 | 50.5 ± 1.1 | 52.8 ± 0.9 |
| M.C.H, pg | 14.5 ± 0.3 | 14.0 ± 0.2 | 14.9 ± 0.3 | 14.6 ± 0.3 | 15.1 ± 0.2 |
| M.C.H.C, g/dL | 29.1 ± 0.5 | 28.3 ± 0.5 | 30.5 ± 0.4 | 29.5 ± 0.4 | 31.0 ± 0.3 |
PLT Platelet, M.C.V Mean Corpuscular Volume, M.C.H Mean Corpuscular Hemoglobin, M.C.H.C Mean Corpuscular Hamoglobin Concentration
*Not detected