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. 1969 Feb;9(2):246–263. doi: 10.1016/S0006-3495(69)86383-6

Cell Growth and Division

IV. Determination of Volume Growth Rate and Division Probability

E C Anderson, G I Bell, D F Petersen, R A Tobey
PMCID: PMC1367431  PMID: 5764232

Abstract

Volume growth rate and division probability functions for mammalian cells have been determined as functions of cell volume with good reproducibility and statistical precision using Coulter volume spectrometry and the equations of the Bell model. Results are compared with independent measurements on synchronous cultures. The slow rate of volume dispersion requires that the growth rate F(τ, V) be closely proportional to volume for cells of a given age. However, when F(τ, V) is averaged over the age distribution of a population in balanced exponential growth to give the growth rate function f(V), the latter may rise more steeply than V.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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