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. 1969 Jul;9(7):954–964. doi: 10.1016/S0006-3495(69)86429-5

Fiber Orientation and Ejection Fraction in the Human Left Ventricle

Edward A Sallin
PMCID: PMC1367490  PMID: 5791550

Abstract

Fiber orientation and ventricular geometry are incorporated in a mathematical model for ejection fraction of the human left ventricle. The inadequacy of circularly oriented or “constrictor” fibers to explain high ejection fractions of cylindrical, spherical, or ellipsoidal reference ventricles is demonstrated. A class of “helical” fibers is then introduced from which ejection fractions predicted by physiologic amounts of fiber shortening on cylindrical and ellipsoidal reference ventricles are shown to be consistent with those calculated from biplane angio-cardiographic films.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brady A. J. Onset of contractility in cardiac muscle. J Physiol. 1966 Jun;184(3):560–580. doi: 10.1113/jphysiol.1966.sp007931. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dodge H. T., Sandler H., Baxley W. A., Hawley R. R. Usefulness and limitations of radiographic methods for determining left ventricular volume. Am J Cardiol. 1966 Jul;18(1):10–24. doi: 10.1016/0002-9149(66)90191-3. [DOI] [PubMed] [Google Scholar]
  3. Kennedy J. W., Baxley W. A., Figley M. M., Dodge H. T., Blackmon J. R. Quantitative angiocardiography. I. The normal left ventricle in man. Circulation. 1966 Aug;34(2):272–278. doi: 10.1161/01.cir.34.2.272. [DOI] [PubMed] [Google Scholar]
  4. Ross J., Jr, Sonnenblick E. H., Covell J. W., Kaiser G., Spiro D. The architecture of the heart in systole and diastole. Technique of rapid fixation and analysis of left ventricular geometry. Circ Res. 1967 Oct;21(4):409–421. doi: 10.1161/01.res.21.4.409. [DOI] [PubMed] [Google Scholar]
  5. SONNENBLICK E. H. Force-velocity relations in mammalian heart muscle. Am J Physiol. 1962 May;202:931–939. doi: 10.1152/ajplegacy.1962.202.5.931. [DOI] [PubMed] [Google Scholar]
  6. SONNENBLICK E. H. INSTANTANEOUS FORCE-VELOCITY-LENGTH DETERMINANTS IN THE CONTRACTION OF HEART MUSCLE. Circ Res. 1965 May;16:441–451. doi: 10.1161/01.res.16.5.441. [DOI] [PubMed] [Google Scholar]
  7. SONNENBLICK E. H. SERIES ELASTIC AND CONTRACTILE ELEMENTS IN HEART MUSCLE: CHANGES IN MUSCLE LENGTH. Am J Physiol. 1964 Dec;207:1330–1338. doi: 10.1152/ajplegacy.1964.207.6.1330. [DOI] [PubMed] [Google Scholar]
  8. Streeter D. D., Jr, Spotnitz H. M., Patel D. P., Ross J., Jr, Sonnenblick E. H. Fiber orientation in the canine left ventricle during diastole and systole. Circ Res. 1969 Mar;24(3):339–347. doi: 10.1161/01.res.24.3.339. [DOI] [PubMed] [Google Scholar]

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