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. 1970 Nov;10(11):1084–1089. doi: 10.1016/S0006-3495(70)86354-8

Electrical Characteristics of Sphingomyelin Bilayer Membranes

J W Kauffman, C A Mead
PMCID: PMC1367984  PMID: 5471699

Abstract

Current-voltage characteristics and the conductivity temperature dependence of sphingomyelin bilayer membranes have been determined. The resistances were of the order of 108 Ω-cm2 and exhibited ohmic behavior up to approximately 25 mv followed by increasing conductivity with applied voltage. The current is found to be proportional to a hyperbolic sine function of the voltage. The temperature dependence indicates a thermally activated conduction mechanism. The observed behavior closely follows a kinetic model involving a barrier modified by the applied electric field, the rate-limiting process being the surmounting of the barrier by the impinging ions. The model allows predictions to be made over a wide range of conditions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. FINEAN J. B. X-ray diffraction studies on the polymorphism of phospholipids. Biochim Biophys Acta. 1953 Mar;10(3):371–384. doi: 10.1016/0006-3002(53)90268-6. [DOI] [PubMed] [Google Scholar]
  2. Hanai T., Haydon D. A., Taylor J. The variation of capacitance and conductance of bimolecular lipid membranes with area. J Theor Biol. 1965 Nov;9(3):433–443. doi: 10.1016/0022-5193(65)90042-1. [DOI] [PubMed] [Google Scholar]
  3. Läuger P., Lesslauer W., Marti E., Richter J. Electrical properties of bimolecular phospholipid membranes. Biochim Biophys Acta. 1967 Feb 1;135(1):20–32. doi: 10.1016/0005-2736(67)90004-1. [DOI] [PubMed] [Google Scholar]
  4. Walz D., Bamberg E., Läuger P. Nonlinear electrical effects in lipid bilayer membranes. I. Ion injection. Biophys J. 1969 Sep;9(9):1150–1159. doi: 10.1016/S0006-3495(69)86442-8. [DOI] [PMC free article] [PubMed] [Google Scholar]

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