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. 1966 Sep;6(5):653–663. doi: 10.1016/S0006-3495(66)86684-5

Electroosmotic Characteristics of Canine Aorta and Vena Cava Wall

Philip N Sawyer, David H Harshaw
PMCID: PMC1368021  PMID: 5970568

Abstract

Experiments in which canine aorta and vena cava walls are subjected to electroosmosis in an open system at constant pressure are described. Electroosmosis reveals that the blood vessel walls studied have a negative zeta potential. The calculated zeta potentials are different for aorta and vena cava, -9.0 ± 5.0 mv compared with -4.7 ± 1.2 mv, respectively, and again of different magnitude with different bathing solutions. The calculated membrane pore charge per centimeter of effective pore surface in statcoulombs is approximately 6.2 × 103 for aorta compared with 3.5 × 103 for vena cava. The implications of the negative electroosmotic zeta potential in terms of the surrounding electric double layer, ion transport, and thrombosis are briefly discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. SAWYER P. N., DEUTCH B. Use of electrical currents to delay intravascular thrombosis in experimental animals. Am J Physiol. 1956 Dec;187(3):473–478. doi: 10.1152/ajplegacy.1956.187.3.473. [DOI] [PubMed] [Google Scholar]
  2. SAWYER P. N., LEVINE J., MAZLEN R., VALMONT I. Active ion transport across canine blood vessel walls. J Gen Physiol. 1961 Nov;45:181–196. doi: 10.1085/jgp.45.2.181. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. SAWYER P. N., PATE J. W. Bio-electric phenomena as an etiologic factor in intravascular thrombosis. Am J Physiol. 1953 Oct;175(1):103–107. doi: 10.1152/ajplegacy.1953.175.1.103. [DOI] [PubMed] [Google Scholar]
  4. SAWYER P. N., SUCKLING E. E., WESOLOWSKI S. A. Effect of small electric currents on intravascular thrombosis in the visualized rat mesentery. Am J Physiol. 1960 May;198:1006–1010. doi: 10.1152/ajplegacy.1960.198.5.1006. [DOI] [PubMed] [Google Scholar]
  5. SAWYER P. N., VALMONT I. Evidence of active ion transport across large canine blood vessel walls. Nature. 1961 Feb 11;189:470–472. doi: 10.1038/189470a0. [DOI] [PubMed] [Google Scholar]
  6. SAWYER P. N., WESOLOWSKI S. A. Studies on direct-current coagulation. Surgery. 1961 Apr;49:486–491. [PubMed] [Google Scholar]
  7. SAWYER P. N., WESOLOWSKI S. A. The electric current of injured tissue and vascular occlusion. Ann Surg. 1961 Jan;153:34–42. doi: 10.1097/00000658-196101000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sawyer P. N., Burrowes C., Ogoniak J., Smith A. O., Wesolowski S. A. Ionic architecture at the vascular wall interface. Trans Am Soc Artif Intern Organs. 1964;10:316–319. [PubMed] [Google Scholar]
  9. TEORELL T. Electrokinetic membrane processes in relation to properties of excitable tissues. I. Experiments on oscillatory transport phenomena in artificial membranes. J Gen Physiol. 1959 Mar 20;42(4):831–845. doi: 10.1085/jgp.42.4.831. [DOI] [PMC free article] [PubMed] [Google Scholar]

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