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. 1964 Jan;170(1):69–85. doi: 10.1113/jphysiol.1964.sp007314

Substance P in brain extracts

Joan Cleugh, J H Gaddum, A A Mitchell, M W Smith, V P Whittaker
PMCID: PMC1368738  PMID: 14135600

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AMBACHE N., REYNOLDS M., WHITING J. M. Investigation of an active lipid in aqueous extracts of rabbit brain, and of some further hydroxy-acids. J Physiol. 1963 Apr;166:251–283. doi: 10.1113/jphysiol.1963.sp007104. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. AMIN A. H., CRAWFORD T. B., GADDUM J. H. The distribution of substance P and 5-hydroxytryptamine in the central nervous system of the dog. J Physiol. 1954 Dec 10;126(3):596–618. doi: 10.1113/jphysiol.1954.sp005229. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BERGSTROM S., SAMUELSSON B. Isolation of prostaglandin E1 from human seminal plasma. Prostaglandins and related factors. 11. J Biol Chem. 1962 Sep;237:3005–3006. [PubMed] [Google Scholar]
  4. BISSET G. W., LEWIS G. P. A spectrum of pharmacological activity in some biologically active peptides. Br J Pharmacol Chemother. 1962 Aug;19:168–182. [PMC free article] [PubMed] [Google Scholar]
  5. BOGOCH S., PAASONEN M. K., TRENDELENBURG U. Some pharmacological properties of brain ganglioside. Br J Pharmacol Chemother. 1962 Apr;18:325–330. doi: 10.1111/j.1476-5381.1962.tb01412.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. CLEUGH J., GADDUM J. H., HOLTON P., LEACH E. Assay of substance P on the fowl rectal caecum. Br J Pharmacol Chemother. 1961 Aug;17:144–158. doi: 10.1111/j.1476-5381.1961.tb01115.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. CLEUGH J., GADDUM J. H. The stability of purified preparations of substance P. Experientia. 1963 Feb 15;19:72–73. doi: 10.1007/BF02148023. [DOI] [PubMed] [Google Scholar]
  8. DOUGLAS W. W., FELDBERG W., PATON W. D. M., SCHACHTER M. Distribution of histamine and substance P in the wall of the dog's digestive tract. J Physiol. 1951 Oct 29;115(2):163–176. doi: 10.1113/jphysiol.1951.sp004661. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. ELIASSON R., LIE L., PERNOW B. A comparative study of substance P from intestine and brain. Br J Pharmacol Chemother. 1956 Jun;11(2):137–140. doi: 10.1111/j.1476-5381.1956.tb01042.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. GADDUM J. H., SZERB J. C. Assay of substance P on goldfish intestine in a microbath. Br J Pharmacol Chemother. 1961 Dec;17:451–463. doi: 10.1111/j.1476-5381.1961.tb01132.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. GADDUM J. H. Tryptamine receptors. J Physiol. 1953 Feb 27;119(2-3):363–368. doi: 10.1113/jphysiol.1953.sp004851. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. GRAY E. G., WHITTAKER V. P. The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. J Anat. 1962 Jan;96:79–88. [PMC free article] [PubMed] [Google Scholar]
  13. Gaddum J. H., Schild H. Depressor substances in extracts of intestine. J Physiol. 1934 Dec 14;83(1):1–14. doi: 10.1113/jphysiol.1934.sp003206. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. HAEFELY W., HUERLIMANN A. Substance P, a highly active naturally occurring polypeptide. Experientia. 1962 Jul 15;18:297–303. doi: 10.1007/BF02151841. [DOI] [PubMed] [Google Scholar]
  15. HEBB C. O., WHITTAKER V. P. Intracellular distributions of acetylcholine and choline acetylase. J Physiol. 1958 Jun 18;142(1):187–196. doi: 10.1113/jphysiol.1958.sp006008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. JOHNSON M. K., WHITTAKER V. P. LACTATE DEHYDROGENASE AS A CYTOPLASMIC MARKER IN BRAIN. Biochem J. 1963 Sep;88:404–409. doi: 10.1042/bj0880404. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. KATAOKA K. The subcellular distribution of substance P in the nervous tissues. Jpn J Physiol. 1962 Feb 15;12:81–96. doi: 10.2170/jjphysiol.12.81. [DOI] [PubMed] [Google Scholar]
  18. LEMBECK F., HOLASEK A. [Intracellular localization of substance P]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1960;238:542–545. [PubMed] [Google Scholar]
  19. PERNOW B. Substance P distribution in the digestive tract. Acta Physiol Scand. 1951;24(2-3):97–102. doi: 10.1111/j.1748-1716.1951.tb00830.x. [DOI] [PubMed] [Google Scholar]
  20. RYALL R. W. Sub-cellular distribution of pharmacologically active substances in guinea pig brain. Nature. 1962 Nov 17;196:680–681. doi: 10.1038/196680a0. [DOI] [PubMed] [Google Scholar]
  21. RYALL R. W. The subcellular distribution of substance of P and 5-HT in brain. Biochem Pharmacol. 1962 Dec;11:1234–1236. doi: 10.1016/0006-2952(62)90201-0. [DOI] [PubMed] [Google Scholar]
  22. TOH C. C. Biologically active substances in brain extracts. J Physiol. 1963 Jan;165:47–61. doi: 10.1113/jphysiol.1963.sp007041. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. V Euler U. S., Gaddum J. H. An unidentified depressor substance in certain tissue extracts. J Physiol. 1931 Jun 6;72(1):74–87. doi: 10.1113/jphysiol.1931.sp002763. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. VOGT W. Naturally occurring lipidsoluble acids of pharmacological interest. Pharmacol Rev. 1958 Sep;10(3):407–435. [PubMed] [Google Scholar]
  25. WHITTAKER V. P. The isolation and characterization of acetylcholine-containing particles from brain. Biochem J. 1959 Aug;72:694–706. doi: 10.1042/bj0720694. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. ZETLER G. New pharmacologically active polypeptides present in impure preparations of substance P. Ann N Y Acad Sci. 1963 Feb 4;104:416–436. doi: 10.1111/j.1749-6632.1963.tb17686.x. [DOI] [PubMed] [Google Scholar]
  27. ZETLER G., SCHLOSSER L. Uber die Verteilung von Substanz P und Cholinacetylase im Gehirn. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1955;224(2):159–175. [PubMed] [Google Scholar]

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