Multiple sequence alignment of Noc1/3/4p proteins. Numbers flanking the alignment correspond to parts of proteins that were aligned. Numbers in parentheses indicate lengths of sequences that were omitted due to insertions or deletions. Protein names are separated by an underscore from species abbreviations: YEAST, Saccharomyces cerevisiae; SCHPO, Schizosaccharmyces pombe; HUMAN, Homo sapiens; ARATH, Arabidopsis thaliana. Letters on the consensus line are: s, small residues; t, tiny; b, big; h, hydrophobic; a, aromatic; l, aliphatic; p, polar; c, charged; −, negatively charged; +, positively charged. Individual residues with more than 80% identity in the entire alignment are colored yellow and shown as capital letters on the consensus line.