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. 1990 Aug;40(337):338–340.

Is the prevalence of atopy increasing?

B Sibbald 1, E Rink 1, M D'Souza 1
PMCID: PMC1371313  PMID: 2121181

Abstract

There is controversy about whether allergic disease has increased in recent decades. This study compared the prevalence of atopy, as shown by allergy skin prick testing among adults in 1988 (n = 74) with a similar study carried out in 1974 (n = 1359). Both study groups were drawn from the general population in south west London, but the 1988 sample specifically excluded people with rhinitis. The proportion of subjects with at least one positive reaction to a panel of three common allergens increased significantly from 23% in 1974 to 46% in 1988 (P less than 0.01). If allowance was made for the exclusion of rhinitis subjects from the 1988 sample, the current prevalence of atopy may be higher still. The increase in prevalence was significant in older subjects (aged 55-59 years) and women but not in other age groups or in men. This small study raises the possibility that atopy has increased in prevalence in the UK over recent decades and additional studies are needed to evaluate the validity of this hypothesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson H. R. Is the prevalence of asthma changing? Arch Dis Child. 1989 Jan;64(1):172–175. doi: 10.1136/adc.64.1.172. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Barbee R. A., Kaltenborn W., Lebowitz M. D., Burrows B. Longitudinal changes in allergen skin test reactivity in a community population sample. J Allergy Clin Immunol. 1987 Jan;79(1):16–24. doi: 10.1016/s0091-6749(87)80010-6. [DOI] [PubMed] [Google Scholar]
  3. Barbee R. A., Lebowitz M. D., Thompson H. C., Burrows B. Immediate skin-test reactivity in a general population sample. Ann Intern Med. 1976 Feb;84(2):129–133. doi: 10.7326/0003-4819-84-2-129. [DOI] [PubMed] [Google Scholar]
  4. Burrows B., Lebowitz M. D., Barbee R. A. Respiratory disorders and allergy skin-test reactions. Ann Intern Med. 1976 Feb;84(2):134–139. doi: 10.7326/0003-4819-84-2-134. [DOI] [PubMed] [Google Scholar]
  5. Chan-Yeung M., Vedal S., Lam S., Enarson D. Immediate skin reactivity and its relationship to age, sex, smoking, and occupational exposure. Arch Environ Health. 1985 Jan-Feb;40(1):53–57. doi: 10.1080/00039896.1985.10545889. [DOI] [PubMed] [Google Scholar]
  6. Cookson W. O., Musk A. W., Ryan G. Associations between asthma history, atopy, and non-specific bronchial responsiveness in young adults. Clin Allergy. 1986 Sep;16(5):425–432. doi: 10.1111/j.1365-2222.1986.tb01977.x. [DOI] [PubMed] [Google Scholar]
  7. Fleming D. M., Crombie D. L. Prevalence of asthma and hay fever in England and Wales. Br Med J (Clin Res Ed) 1987 Jan 31;294(6567):279–283. doi: 10.1136/bmj.294.6567.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Freidhoff L. R., Meyers D. A., Bias W. B., Chase G. A., Hussain R., Marsh D. G. A genetic-epidemiologic study of human immune responsiveness to allergens in an industrial population: I. Epidemiology of reported allergy and skin-test positivity. Am J Med Genet. 1981;9(4):323–340. doi: 10.1002/ajmg.1320090409. [DOI] [PubMed] [Google Scholar]
  9. Godfrey R. C., Griffiths M. The prevalence of immediate positive skin tests to Dermatophagoides pteronyssinus and grass pollen in schoolchildren. Clin Allergy. 1976 Jan;6(1):79–82. doi: 10.1111/j.1365-2222.1976.tb01415.x. [DOI] [PubMed] [Google Scholar]
  10. Greenberg M., Milne J. F., Watt A. Survey of workers exposed to dusts containing derivatives of Bacillus subtilis. Br Med J. 1970 Jun 13;2(5710):629–633. doi: 10.1136/bmj.2.5710.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Haahtela T., Heiskala M., Suoniemi I. Allergic disorders and immediate skin test reactivity in Finnish adolescents. Allergy. 1980 Jul;35(5):433–441. doi: 10.1111/j.1398-9995.1980.tb01790.x. [DOI] [PubMed] [Google Scholar]
  12. Peat J. K., Britton W. J., Salome C. M., Woolcock A. J. Bronchial hyperresponsiveness in two populations of Australian schoolchildren. III. Effect of exposure to environmental allergens. Clin Allergy. 1987 Jul;17(4):291–300. doi: 10.1111/j.1365-2222.1987.tb02017.x. [DOI] [PubMed] [Google Scholar]
  13. Sibbald B., Rink E. Birth month variation in atopic and non-atopic rhinitis. Clin Exp Allergy. 1990 May;20(3):285–288. doi: 10.1111/j.1365-2222.1990.tb02685.x. [DOI] [PubMed] [Google Scholar]
  14. Woolcock A. J., Colman M. H., Jones M. W. Atopy and bronchial reactivity in Australian and Melanesian populations. Clin Allergy. 1978 Mar;8(2):155–164. doi: 10.1111/j.1365-2222.1978.tb00460.x. [DOI] [PubMed] [Google Scholar]
  15. Zetterström O. The increased prevalence of allergic airway disease. Allergy. 1988;43 (Suppl 8):10–11. doi: 10.1111/j.1398-9995.1988.tb02435.x. [DOI] [PubMed] [Google Scholar]

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