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[Preprint]. 2026 Oct 22:2026.10.21.760778. [Version 1] doi: 10.64898/2026.10.21.760778

NuFold RNA Structure Database: Large-Scale RNA Tertiary Structure Prediction with Confidence Metrics

David Platt, Yuki Kagaya, Daisuke Kihara
PMCID: PMC13738726  PMID: 42996115

Abstract

Summary

To bridge the gap between rapid RNA sequence discovery and slow experimental characterization, we present the NuFold RNA Structure Database ( https://nufold.kiharalab.org/ ), a resource providing large-scale, precomputed full-atom RNA tertiary structures. By removing the computational barriers associated with running the method locally, this database makes high-accuracy RNA structure models readily accessible to the biological research community for a wide range of applications.

Availability and implementation

All predicted structures and corresponding data are available at https://nufold.kiharalab.org/ . The source code for the NuFold program is available at https://github.com/kiharalab/NuFold .

Supplementary Information

For more insight into resulting statistics gathered for this project, see https://nufold.kiharalab.org/statistics . For more insight into how to utilize the webserver itself, see https://nufold.kiharalab.org/faq and https://nufold.kiharalab.org/tutorial .

Full Text

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